Database : HANSEN Search on : INOCULACOES SERIADAS/UTIL [Subject descriptor] References found : 2 [refine] Displaying: 1 .. 2   in format [Detailed]

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Id: 17341 Author: Avelleira, Joao Carlos Regazzi; Vianna, Francisco Reis; Boechat, Alfredo Marques; Alves, Larissa Mitraud; Madeira, Suzana. Title: Persistence of viable bacilli in highly bacilliferous multibacillary leprosy patients after the twelve doses of multidrug therapy WHO/MDT. Source: Hansen. Int;28(1):49-52, jan.-jun. 2003. tab. Abstract: The present study evaluate efficacy of twelve doses of multidrug therapy, as suggested by World Health Organization, in ten lepromatous leprosy patients with bacilloscopic index equal or higher than 4. The patients have taken the doses in twelve month-doses regularly. At the end od treatment a specimen was collected by punch biopsy and inoculated into mouse hind footpad acoording to Shepard's technique. Persistence of viable bacilli was demonstrated in three patients. In spite of the small number of patients, same results have been found by other authors, showing that in highly bacilliferous leprosy patients, at the beginning of treatment more doses may be required to prevent relapses. (AU). Descriptors: HANSENIASE/quimioter HANSENIASE/microbiol MYCOBACTERIUM LEPRAE/ef drogas MYCOBACTERIUM LEPRAE/cresc MYCOBACTERIUM LEPRAE/isol MICROBIOLOGIA - INOCULACOES SERIADAS/métodos  INOCULACOES SERIADAS/util Electronic Medium: http://hansen.bvs.ilsl.br/textoc/hansenint/v21aov29/2003/PDF/v28n1/v28n1a3eng.pdf / pt Location: BR191.1

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Id: 17340 Author: Avelleira, Joao Carlos Regazzi; Vianna, Francisco Reis; Boechat, Alfredo Marques; Alves, Larissa Mitraud; Madeira, Suzana. Title: Persistencia de bacilos viaveis em pacientes de hanseniase multibacilar altamente baciliferos apos doze doses do esquema poliquimioterapico (PQT/OMS) / Persistence of viable bacilli in highly bacilliferous multibacillary leprosy patients after the twelve doses of multidrug therapy WHO/MDT Source: Hansen. Int;28(1):44-48, jan.-jun. 2003. ilus, tab. Abstract: Trabalho de investigacao, com o obejtivo de avaliar a eficacia do tratamento de doze doses com o esquema poliquimioterapico proposto pela Organizacao Mundial da Saude em 10 pacientes de hanseniase virchoviana em indice baciloscopico igual ou maior que 4. Os pacientes foram submetidos ao tratamento por 12 meses, regularmente. Apos o final do tratamento, foi feita retirada de material e inoculacao em coxim plantar de camundongos, conforme a tecnica de Shepard. Os resultados mostraram persistencia de bacilos viaveis em tres pacientes. Os autores, apesar da amostra pequena, observam que os mesmos resultados tem sido encontrados por outros autores surgerindo que talves seja necessario tratar os pacientes com altos indices baciloscopico no inicio do tratamento, por mais tempo, na tentativa de evitar possiveis recidivas. (AU). Descriptors: HANSENIASE/quimioter HANSENIASE/microbiol MYCOBACTERIUM LEPRAE/ef drogas MYCOBACTERIUM LEPRAE/cresc MYCOBACTERIUM LEPRAE/isol MICROBIOLOGIA - INOCULACOES SERIADAS/métodos  INOCULACOES SERIADAS/util Electronic Medium: http://hansen.bvs.ilsl.br/textoc/hansenint/v21aov29/2003/PDF/v28n1/v28n1a03.pdf / pt Location: BR191.1

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