Database : HANSEN Search on : DNA BACTERIANO/QUIM [Subject descriptor] References found : 3 [refine] Displaying: 1 .. 3   in format [Detailed]

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Id: 19844 Author: Cole, Stewart T. Title: The Mycobacterium leprae genome projest. Source: Int. J. Lepr;66(4):589-591, Dec. 1998. . Conference: Present in: International Leprosy Congress, 15, Beijing, 07-12 Sept. 1998. Descriptors: Mycobacterium leprae/genet DNA Bacteriano/quim Electronic Medium: http://hansen.bvs.ilsl.br/textoc/revistas/intjlepr/1998/pdf/v66n4/v66n4repcur03.pdf / en Location: BR191.1

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Id: 13953 Author: Kim, Se -Kon; Lee, Seong- Beom; Kang, Tae -Jin; Chae, Gue -Tae Title: Detection of gene mutations related with drug resistance in Mycobacterium leprae from leprosy patients using Touch-Down (TD) PCR ..- Source: s.l; s.n; 2003. 6 p. ilus, tab. Abstract: The lack of methods to identify Mycobacterium leprae with the resistance against multi-drugs quickly and specifically has hindered effective chemotherapy against M. leprae infection. To screen M. leprae with resistance against multi-drugs, the Touch-Down (TD)-PCR has been used in this study. Sequences of the folP, rpoA, B, and gyrA, B genes were analyzed for isolates of M. leprae from leprosy patients in Korea. We amplified designated region of several genes in M. leprae involved in drug resistance and could obtain the PCR products of each gene. The mutations in the particular region of folP, rpoB, and gyrB gene were certified by TD-PCR single-stranded conformational polymorphism and DNA sequencing, respectively. (AU). Descriptors: DNA BACTERIANO/quim DNA BACTERIANO/genet Resistência Bacteriana a Múltiplas Drogas/genet COREIA (GEOGRAFICO) HANSENOSTATICOS/farmacol HANSENIASE/quimioter HANSENIASE/microbiol MYCOBACTERIUM LEPRAE/genet MUTACAO PUNTUAL REACAO EM CADEIA DA POLIMERASE/métodos POLIMORFISMO (GENETICA) POLIMORFISMO CONFORMACIONAL DE SIMPLES FITA ANALISE DE SEQUÊNCIA DE DNA Limits: HUMANO SUPPORT, NON-U.S. GOV'T Electronic Medium: http://www.ilsl.br Location: BR191.1; 09096/s

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Id: 11690 Author: Shin, Yoo-Chul; Lee, Hyejon; Lee, Hyeyoung; Walsh, Gerald P; Kim, Joo-Deuk; Cho, Sang-Nae Title: Variable numbers of TTC repeats in Mycobacterium leprae DNA from leprosy patients and use in strain differentiation ..- Source: s.l; s.n; 2000. 4 p. ilus, tab. Descriptors: HANSENIASE HANSENIASE MYCOBACTERIUM LEPRAE MYCOBACTERIUM LEPRAE AUTO-RADIOGRAFIA DNA BACTERIANO REAÇAO EM CADEIA POR POLIMERASE REPRODUTIBILIDADE DE RESULTADOS REPETIÇOES DE TRINUCLEOTIDIOS Location: BR191.1; 08482/s

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