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| Id: | 18151
| | Author: | Costa, A; Nery, J; Oliveira, M; Cuzzi, T; Silva, M
| | Title: | Oral lesions in leprosy
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| | Source: | s.l; s.n; 2003. 11 p. ilus, tab.
| | Abstract: | BACKGROUND: Leprotic oral lesions are more common in the lepromatous form of leprosy, indicate a late manifestation, and have a great epidemiological importance as a source of infection. METHODS: Patients wit leprosy were examined searching for oral lesions. Biopsies of the left buccal mucosa in all patients, and of oral lesions, were performed and were stained with H&E and Wade. Results: Oral lesions were found in 26 patients, 11 lepromatous leprosy, 14 borderline leprosy, and one tuberculoid leprosy. Clinically 5 patients ha enanthem of the anterior pillars, 3 of the uvula and 3 of the palate. Two had palatal infiltration. Viable bacilli were found in two lepromatous patients. biopsies of the buccal mucosa showed no change or a nonspecific inflammatory infiltrate. Oral clinical alterations were present in 69 POR cento of the patients; of these 50% showed histopathological features in an area without any lesion. DISCUSSION: Our clinical and histophatological findings corroborate earlier reports that thereis a reduced incidence of oral changes, which is probably due t early treatment. The maintenance of oral infection in this are can also lead to and maintain lepra reactions, while they may also act as possible infection sources. Attention should be given to oral disease in leprosy because detection and treatment of oral lesions can prevent the spread of the disease (AU).
| | Descriptors: | HANSENIASE/epidemiol
HANSENIASE/microbiol
HANSENIASE/fisiopatol
MUCOSA BUCAL/anat
MUCOSA BUCAL/les
| | Limits: | ESTUDO COMPARATIVO
HUMANO
| | Location: | BR191.1; 02183/s |
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