Database : HANSEN
Search on : ANEMIA/EPIDEMIOL [Subject descriptor]
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Id:15627
Author:Kaluarachchi, S. I; Fernandopulle, B. M. R; Gunawardane, B. P
Title:Hepatic and haematological adverse reactions associated with the use of multidrug therapy in leprosy - a five year retrospective study ..-
Source:s.l; s.n; 2001. 9 p. tab.
Abstract:This study analyses retrospectively some of the risks associated with the use of WHO-multidrug therapy (MDT) in Sri Lanka. Case records of 3,333 new cases of leprosy attending the Central Leprosy Clinic in Colombo during 1991-1995, were analysed for adverse drug reactions involving the liver and blood. There were 81 reports of suspected hepatic or haematological adverse reactions associated with the use of MDT, of which 39 were classified as haemolytic anaemia, 25 as toxic hepatitis, 2 as methaemoglobinaemia and 15 as anaemia. Dapsone, was incriminated in the majority of adverse reactions (72 per cent). Adverse drug reactions were more common in female than male subjects (55 per cent vs 45 per cent; P < 0.5), but there was no significant differences between the age groups. Majority of adverse reactions was seen within the first three months of initiation of MDT. This study in no way undermines the benefits of MDT but highlights the risks and suggests measures to minimize these risks. (AU).
Descriptors:ANEMIA/ind quim
ANEMIA/epidemiol
CLOFAZIMINA/ef adv
DAPSONA/ef adv
QUIMIOTERAPIA COMBINADA
HEPATITE TOXICA/epidemiol
HANSENOSTATICOS/ef adv
HANSENOSTATICOS/uso terap
HANSENIASE/quimioter
ESTUDOS RETROSPECTIVOS
RIFAMPINA/ef adv
RIFAMPINA/uso terap
METEMOGLOBINEMIA/ind quim
METEMOGLOBINEMIA/epidemiol
Limits:HUMANO
MASCULINO
FEMININO
CRIANÇA
ADULTO
MEIA-IDADE
ADOLESCENTE
Electronic Medium:http://www.ilsl.br
Location:BR191.1; 09163/s


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Id:13662
Author:Bastien, Patrick
Title:Public-health epidemiology in Vanuatu ..-
Source:s.l; s.n; Jan. 1990. 5 p. mapas, tab, graf.
Abstract:Vanuatu, which formerly was known as the New Hebrides, is an archipelago in the southwest Pacific Ocean with a tropical humid climate. The national health system and the state of health of the population generally are satisfactory. The main diseases of public-health importance are malaria and tuberculosis. Their epidemiology and control are discussed. An epidemic of Plasmodium falciparum malaria, which commenced in 1980, is described; this possibly can be explained by an increase in chloroquine-resistant P. falciparum over the same period. Other diseases also are reviewed. Many tropical diseases of great significance elsewhere are not of much significance in Vanuatu. Medical advice for visiting travellers is provided. (AU).
Descriptors:ANEMIA/epidemiol
DOENCAS CARDIOVASCULARES/epidemiol
CLOROQUINA/uso terap
HANSENIASE/epidemiol
RESISTÊNCIA A DROGAS
MALARIA/quimioter
MALARIA/epidemiol
MALARIA/prev
PROGRAMAS NACIONAIS DE SAUDE/org
PLASMODIUM FALCIPARUM/ef drogas
PLASMODIUM FALCIPARUM/isol
NEOPLASIAS/epidemiol
TUBERCULOSE/epidemiol
VANUATU
INCIDÊNCIA
 VIAGEM
Limits:HUMANO
ANIMAL
MASCULINO
RECÉM-NASCIDO
LACTENTE
PRÉ-ESCOLAR
CRIANÇA
ADOLESCENTE
Electronic Medium:http://www.ilsl.br
Location:BR191.1; 09122/s


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Id:13655
Author:Kaluarachchi, S. I; Fernandopulle, B. M. R; Gunawardane, B. P
Title:Hepatic and haematological adverse reactions associated with the use of multidrug therapy in leprosy - a five year retrospective study ..-
Source:s.l; s.n; 2001. 9 p. tab.
Abstract:This study analyses retrospectively some of the risks associated with the use of WHO-multidrug therapy (MDT) in Sri Lanka. Case records of 3,333 new cases of leprosy attending the Central Leprosy Clinic in Colombo during 1991-1995, were analysed for adverse drug reactions involving the liver and blood. There were 81 reports of suspected hepatic or haematological adverse reactions associated with the use of MDT, of which 39 were classified as haemolytic anaemia, 25 as toxic hepatitis, 2 as methaemoglobinaemia and 15 as anaemia. Dapsone, was incriminated in the majority of adverse reactions (72 per cent). Adverse drug reactions were more common in female than male subjects (55 per cent vs 45 per cent; P < 0.5), but there was no significant differences between the age groups. Majority of adverse reactions was seen within the first three months of initiation of MDT. This study in no way undermines the benefits of MDT but highlights the risks and suggests measures to minimize these risks. (AU).
Descriptors:ANEMIA/ind quim
ANEMIA/epidemiol
CLOFAZIMINA/ef adv
DAPSONA/ef adv
QUIMIOTERAPIA COMBINADA
HEPATITE TOXICA/epidemiol
HANSENOSTATICOS/ef adv
HANSENOSTATICOS/uso terap
HANSENIASE/quimioter
METEMOGLOBINEMIA/ind quim
METEMOGLOBINEMIA/epidemiol
ESTUDOS RETROSPECTIVOS
RIFAMPINA/ef adv
RIFAMPINA/uso terap
Limits:HUMANO
MASCULINO
FEMININO
CRIANÇA
ADULTO
ADOLESCENTE
Electronic Medium:http://www.ilsl.br
Location:BR191.1; 09123/s


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Id:9294
Author:Coura, Academico Jose Rodrigues; Willcox, Henry P. F; Albuquerque, Bernardino C. de; Lorenzi, Andre G. de; Barroso, David E; Lalama, Eduardo M. Espinel; Goncalves, Eloisa G. R; Guerra, Jorge Augusto O; Marin, Miguel A. Vaca; Sa Neto, Raimundo P
Title:Aspectos epidemiologicos, sociais e sanitarios em areas do Medio Solimoes. I. Estudo das localidades de Sao Francisco do Laranjal, Aranai e Sao Lazaro do Surubim, municipio de Coari, Amazonas ?-
Source:s.l; s.n; 1993. 5 p. ilus, tab.
Descriptors:DOENÇAS PARASITARIAS
HEPATITE B
HANSENIASE
ANEMIA
BRASIL
PREVALENCIA
ZONAS RURAIS
SAUDE AMBIENTAL
Location:BR191.1; 06225/s



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