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| Id: | 13286
| | Author: | Sunderland, Sidney
| | Title: | The internal anatomy of nerve trunks in relation to the neural lesions of leprosy
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| | Source: | s.l; s.n; dec. 1973. 23 p. ilus, tab.
| | Abstract: | The internal anatoly of peripheral nerve trunks has been studied and discussed in relation to some features of the neural lesions of leprosy. Special significance is attached to the perineurium, funicular structure and the intraneural funicular plexuses.The perineurium controls the spread of the micro-organisms confining them, for some time, to the affected funiculi and promoting their movement centrally along the bundles. By the time the outlines of the perineurium have been lost and the epineurium involved at any level, the micro-organisms are likley to have advanced considerable distances up the bundles.Because of the elastic resistance of the perineurium, the pressure inside the bundle builds up as the products of the inflammatory reaction slowly accumulate. Compression and ischemia of the contents of the bundle introduced in this way add to the involvement and destruction of nerve fibres due directly to the activity of the M. leprae.(AU).
| | Descriptors: | TECIDO CONJUNTIVO/patol
ISQUEMIA
HANSENIASE/compl
HANSENIASE/imunol
HANSENIASE/microbiol
HANSENIASE/patol
HANSENIASE/fisiopatol
HANSENIASE/cirurg
MYCOBACTERIUM LEPRAE/patogen
CELULAS DE SCHWANN
- PRESSAO
SENSACAO
| | Electronic Medium: | http://www.ilsl.br
| | Location: | BR191.1; 00529/s |
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