Database : HANSEN
Search on : TUBERCULOSE PULMONAR/DIAG [Subject descriptor]
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Id:13666
Author:Bala, Lakshmi; Anand, Sukumar; Sinha, Sudhir
Title:Enhancement of human T cell response to a peptide epitope of 38kDa antigen of Mycobacterium tuberculosis by liposomes ..-
Source:s.l; s.n; 2002. 9 p. graf.
Abstract:Diagnosis of tuberculosis a problem, specially in the regions harboring an abundance of both pathogenic and non-pathogenic mycobacteria. This study was undertaken to assess in such a situation the predictive value of proliferative T cell response to a peptide epitope ('38G') of the 38 kDa membrane protein of Mycobacterium tuberculosis. 3[H]-thymidine incorporation assays were done with peripheral blood mononuclear cells of tuberculoid leprosy and pulmonary tuberculosis patients. The donors were also classified as PPD responders (Stimulation Index, SI> 3) or non-responders (SI < or = 3) on the basis of their T cell response to the 'Purified Protein Derivative (PPD)' of M. tuberculosis. 38G peptide was used in either free or liposome-associated form prepared by the technique of 'Dehydration-rehydration Vesicles' (Kirby and Gregoriadis, 1984). While free peptide failed to induce a positive response in study subjects, its liposomal form was T cell stimulatory and distinguished, to certain extent, between PPD responders (corresponding SI > 3 in 54 per cent subjects) and non-responders (SI > 3 in 29 per cent subjects). However, it did not differentiate between leprosy and tuberculosis. The study supports use of liposomes as adjuvant vehicles for antigenic peptides designed to activate human T cells. (AU).
Descriptors:ANTIGENOS DE BACTERIAS/admin
ANTIGENOS DE BACTERIAS/quim
ANTIGENOS DE BACTERIAS/genet
HANSENIASE TUBERCULOIDE/diag
HANSENIASE TUBERCULOIDE/imunol
EPITOPOS/admin
EPITOPOS/quim
EPITOPOS/genet
DIAGNOSTICO DIFERENCIAL
MYCOBACTERIUM TUBERCULOSIS/quim
MYCOBACTERIUM TUBERCULOSIS/genet
MYCOBACTERIUM TUBERCULOSIS/imunol
DADOS DE SEQUÊNCIA MOLECULAR
SEQUÊNCIA DE AMINOACIDOS
LINFOCITOS T/imunol
TESTE TUBERCULINICO
TUBERCULOSE PULMONAR/diag
TUBERCULOSE PULMONAR/imunol
TRANSFORMACAO LINFOCITICA
LIPOSSOMOS
 PESO MOLECULAR
Limits:ESTUDO COMPARATIVO
HUMANO
IN VITRO
SUPPORT, NON-U.S. GOV'T
Electronic Medium:http://www.ilsl.br
Location:BR191.1; 09061/s


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Id:9822
Author:Kaushik, N. K; Sharma, Parul; Shah, Ashok; Venkitasubramanian, T. A
Title:Serodiagnostic efficiency of phospholipid associated protein of Mycobacterium tuberculosis H37Rv ..-
Source:s.l; s.n; 1993. 11 p. ilus, tab, graf.
Descriptors:HANSENIASE LEPROMATOSA
MYCOBACTERIUM TUBERCULOSIS
ANTICORPOS ANTIBACTÉRIAS
PROTEINAS DE BACTÉRIAS
CROMATOGRAFIA EM CAMADA DELGADA
ELISA
REAÇOES FALSO-POSITIVAS
IGG
FOSFOLIPIDIOS
VALOR PREDITIVO DOS TESTES
RINITE
SENSIBILIDADE E ESPECIFICIDADE
TUBERCULOSE PULMONAR
Location:BR191.1; 06726/s


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Id:9757
Author:Caminero, J. A; Rodriguez de Castro, F; Carrillo, T; Lafarga, B; Diaz, F; Cabrera, P
Title:Value of ELISA using A60 antigen in the serodiagnosis of tuberculosis ..-
Source:s.l; s.n; 1994. 4 p. tab.
Descriptors:HANSENIASE LEPROMATOSA
ANTICORPOS
ELISA
IGG
SENSIBILIDADE E ESPECIFICIDADE
TUBERCULINA
TUBERCULOSE
TUBERCULOSE PULMONAR
Limits:HUMANO
FEMININO
ADULTO
MEIA-IDADE
MASCULINO
Location:BR191.1; 06692/s


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Id:9716
Author:Sanchez Monton, T; Martin Luengo, F
Title:Serodiagnostico en la tuberculosis pulmonar. Valoracion clinica ..-
Source:s.l; s.n; 1992. 5 p. tab, graf.
Descriptors:ANTICORPOS ANTIBACTÉRIAS
ESPECIFICIDADE DE ANTICORPOS
ANTIGENOS DE BACTÉRIAS
ESTUDOS DE CASOS E CONTROLES
ELISA
ESTUDOS DE AVALIAÇAO
IMUNOGLOBULINAS
IMUNOGLOBULINAS
HANSENIASE
PNEUMOPATIAS
MYCOBACTERIUM TUBERCULOSIS
MYCOBACTERIUM TUBERCULOSIS
VALOR PREDITIVO DOS TESTES
SENSIBILIDADE E ESPECIFICIDADE
ESCARRO
TUBERCULOSE PULMONAR
TUBERCULOSE PULMONAR
TUBERCULOSE PULMONAR
Location:BR191.1; 06514/s


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Id:9715
Author:Sood, J; Gupta, O. P; Narang, P; Cheirmaraj, K; Reddy, M. V. R; Harinath, B. C
Title:Penicillinase ELISA for detection of tubercular antigen in tuberculosis ..-
Source:s.l; s.n; 1991. 5 p. tab.
Descriptors:ANTIGENOS DE BACTÉRIAS
ANTIGENOS DE BACTÉRIAS
ELISA
HANSENIASE
MYCOBACTERIUM TUBERCULOSIS
PENICILINASE
VALOR PREDITIVO DOS TESTES
TUBERCULOSE MENINGEA
TUBERCULOSE PULMONAR
Location:BR191.1; 06513/s


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Id:9334
Author:Coker, R. J; Hellyer, T. J; Brown, I. N; Weber, J. N
Title:Clinical aspects of mycobacterial infections in HIV infection ..-
Source:s.l; s.n; 1992. 5 p. .
Descriptors:INFECÇOES OPORTUNISTAS RELACIONADAS COM A AIDS
INFECÇOES OPORTUNISTAS RELACIONADAS COM A AIDS
INFECÇOES OPORTUNISTAS RELACIONADAS COM A AIDS
SINDROME DE IMUNODEFICIENCIA ADQUIRIDA
ANTIBIOTICOS COMBINADOS
HANSENIASE
MICOBACTERIOSE ATIPICA
INFECÇAO POR MYCOBACTERIUM AVIUM-INTRACELLULARE
INFECÇAO POR MYCOBACTERIUM AVIUM-INTRACELLULARE
INFECÇAO POR MYCOBACTERIUM AVIUM-INTRACELLULARE
TUBERCULOSE
TUBERCULOSE
TUBERCULOSE
TUBERCULOSE PULMONAR
TUBERCULOSE PULMONAR
TUBERCULOSE PULMONAR
Location:BR191.1; 06468/s


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Id:9088
Author:Fortunato, R. M; Tomimore, J. Y; Sotto, M. N; Alchorne, M. M. A
Title:Associacao da hanseniase com tuberculose pulmonar ?-
Source:s.l; s.n; 1992. 1 p. .
Conference:Present in: Congresso Brasileiro de Dermatologia, 47, Rio de Janeiro, 1992.
Descriptors:HANSENIASE
TUBERCULOSE PULMONAR
Location:BR191.1; 06043/s


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Id:7836
Author:Corrêa, Guacira Nogueira
Title:Diagnóstico laboratorial da tuberculose pulmonar: análise de métodos tradicionais aplicados a escarro de pacientes sem causa básica conhecida de imunossupressao e de doentes com aids. Comparaçao do padrao de sensibilidade a drogas das cepas de Mycobacterium tuberculosis isoladas Laboratorial diagnosis of pulmonar tuberculosis-
Source:Botucatu; s.n; 1998. 75 p. ilus, tab.
Thesis:Present for Universidade Estadual Paulista. Faculdade de Medicina do Campus de Botucatu presented for the degree Mestre.
Abstract:Foi realizado o estudo baciloscópico em até três amostras de material orgânico e/ou antibiogramas de cepas de Mycobacterium tuberculosis isoladas de 56 pacientes, 29 sem causa básica conhecida de imunossupressao (G1) e 27 com aids (G2). O estudo baciloscópico foi realizado em escarros descontaminados e concentrados de 17 pacientes de G1 e 21 pacientes de G2, com tuberculose pulmonar confirmada pelo isolamento do agente etiológico. Os antibiogramas foram realizados em 20 cepas isoladas de pacientes de G1 e em outras 20 isoladas de pacientes de G2, sendo utilizado o método das proporçoes e o meio de Loewenstein-Jenssen. As drogas testadas foram estreptomicina, etambutol, isoniazida e rifampicina(AU).
Descriptors:TUBERCULOSE PULMONAR
TUBERCULOSE PULMONAR
TUBERCULOSE PULMONAR
SINDROME DE IMUNODEFICIENCIA ADQUIRIDA
RESISTENCIA A DROGAS
INFECÇAO
HIV
MYCOBACTERIUM TUBERCULOSIS
Location:BR191.1; WF300, C817d



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