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| Id: | 13701
| | Author: | Singh, Navjeevan; Arora, V. K; Jain, Annu; Bhattacharya, S. N; Bhatia, Arati
| | Title: | Cytology of testicular changes in leprosy
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| | Source: | s.l; s.n; 2002. 5 p. ilus, tab.
| | Abstract: | OBJECTIVE: To study the changes in testicular aspirates and semen of patients with leprosy. STUDY DESIGN: A prospective study of 56 patients in the reproductive-age group, with no record of treatment for leprosy. Both Ridley-Jopling and WHO classification systems were used. Skin and/or nerve biopsies were performed for documentation of the diagnosis. Semen analysis and fine needle aspirates of the testes were performed. Smears from the testicular aspirates were stained with May-Grünwald-Giemsa and Ziehl-Neelsen stain. RESULTS: Five patients were unable to produce an ejaculate. Abnormal semen analysis and/or testicular aspirates were seen in 24 (42.8 per cent) patients. Eleven had oligospermia and eight azoospermia. Abnormalities in testicular aspirates ranged from hypospermatogenesis (4) through maturation arrest (1) and atrophy (11). Two patients had hydrocoele, and two had associated microfilariae. Three patients with multibacillary leprosy had type 2 reaction. Mycobacterium lepre was demonstrable in testicular aspirates from all patients with multibacillary and in three with paucibacillary leprosy. CONCLUSION: Abnormal semen analysis and/or testicular aspirates occur in a very high percentage of patients with leprosy. While this is expected for multibacillary disease, the high incidence in the paucibacillary form was surprising. With the rapid elimination of leprosy, fertility-related disability might emerge as a major problem in these people. (AU).
| | Descriptors: | BIOPSIA POR AGULHA
HANSENIASE/microbiol
HANSENIASE/patol
SÊMEN/citol
ESPERMATOGÊNESE
TESTICULO/patol
| | Limits: | HUMANO
MASCULINO
ADULTO
| | Electronic Medium: | http://www.ilsl.br
| | Location: | BR191.1; 09008/s |
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