Database : HANSEN Search on : ANTIGENOS DE BACTERIAS/GENET [Subject descriptor] References found : 18 [refine] Displaying: 1 .. 18   in format [Detailed]

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Id: 13666 Author: Bala, Lakshmi; Anand, Sukumar; Sinha, Sudhir Title: Enhancement of human T cell response to a peptide epitope of 38kDa antigen of Mycobacterium tuberculosis by liposomes ..- Source: s.l; s.n; 2002. 9 p. graf. Abstract: Diagnosis of tuberculosis a problem, specially in the regions harboring an abundance of both pathogenic and non-pathogenic mycobacteria. This study was undertaken to assess in such a situation the predictive value of proliferative T cell response to a peptide epitope ('38G') of the 38 kDa membrane protein of Mycobacterium tuberculosis. 3[H]-thymidine incorporation assays were done with peripheral blood mononuclear cells of tuberculoid leprosy and pulmonary tuberculosis patients. The donors were also classified as PPD responders (Stimulation Index, SI> 3) or non-responders (SI < or = 3) on the basis of their T cell response to the 'Purified Protein Derivative (PPD)' of M. tuberculosis. 38G peptide was used in either free or liposome-associated form prepared by the technique of 'Dehydration-rehydration Vesicles' (Kirby and Gregoriadis, 1984). While free peptide failed to induce a positive response in study subjects, its liposomal form was T cell stimulatory and distinguished, to certain extent, between PPD responders (corresponding SI > 3 in 54 per cent subjects) and non-responders (SI > 3 in 29 per cent subjects). However, it did not differentiate between leprosy and tuberculosis. The study supports use of liposomes as adjuvant vehicles for antigenic peptides designed to activate human T cells. (AU). Descriptors: ANTIGENOS DE BACTERIAS/admin ANTIGENOS DE BACTERIAS/quim ANTIGENOS DE BACTERIAS/genet HANSENIASE TUBERCULOIDE/diag HANSENIASE TUBERCULOIDE/imunol EPITOPOS/admin EPITOPOS/quim EPITOPOS/genet DIAGNOSTICO DIFERENCIAL MYCOBACTERIUM TUBERCULOSIS/quim MYCOBACTERIUM TUBERCULOSIS/genet MYCOBACTERIUM TUBERCULOSIS/imunol DADOS DE SEQUÊNCIA MOLECULAR SEQUÊNCIA DE AMINOACIDOS LINFOCITOS T/imunol TESTE TUBERCULINICO TUBERCULOSE PULMONAR/diag TUBERCULOSE PULMONAR/imunol TRANSFORMACAO LINFOCITICA - LIPOSSOMOS  PESO MOLECULAR Limits: ESTUDO COMPARATIVO HUMANO IN VITRO SUPPORT, NON-U.S. GOV'T Electronic Medium: http://www.ilsl.br Location: BR191.1; 09061/s

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Id: 12297 Author: Spencer, John S; Marques, Maria Angela M; Lima, Monica C. B. S; Junqueira_Kipnis, Ana Paula; Gregory, Bruce C; Truman, Richard W; Brennan, Patrick J Title: Antigenic specificity of the mycobacterium leprae homologue of ESAT-6 ..- Source: s.l; s.n; Feb. 2002. 4 p. tab, graf. Descriptors: SEQUENCIA DE AMINOACIDOS ESPECIFICIDADE DE ANTICORPOS ANTIGENOS DE BACTÉRIAS ANTIGENOS DE BACTÉRIAS ANTIGENOS DE BACTÉRIAS ANTIGENOS DE BACTÉRIAS CLONAGEM MOLECULAR EPITOPOS DE LINFOCITO B EPITOPOS DE LINFOCITO B EPITOPOS DE LINFOCITO T EPITOPOS DE LINFOCITO T HANSENIASE CAMUNDONGOS CAMUNDONGOS ENDOGAMICOS BALB C DADOS DE SEQUENCIA MOLECULAR Limits: ANIMAL Location: BR191.1; 08667/s

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Id: 12292 Author: Ohara, Naoya; Matsuoka, Masanori; Nomaguchi, Hiroko; Naito, Mariko; Yamada, Takeshi Title: Protective responses against experimental mycobacterium leprae infection in mice induced by recombinant Bacillus Calmette-Guérin over-producing three putative protective antigen candidates ..- Source: s.l; s.n; Feb. 2001. 5 p. ilus, graf. Descriptors: ANTIGENOS DE BACTÉRIAS VACINA BCG VACINA BCG VACINA BCG SEQUENCIA DE BASES PRIMERS DO DNA HANSENIASE HANSENIASE CAMUNDONGOS CAMUNDONGOS ENDOGAMICOS BALB C CAMUNDONGOS ENDOGAMICOS C57BL MYCOBACTERIUM BOVIS MYCOBACTERIUM BOVIS Limits: ANIMAL Location: BR191.1; 08623/s

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Id: 11939 Author: Meada, Yumi; Makino, Masahiko; Crick, Dean C; Mahapatra, Sebabrata; Srisungnam, Sopa; Takii, Takemasa; Kashiwabara, Yoshiko; Brennan, Partrick J Title: Novel 33-kilodalton lipoprotein from Mycobacterium leprae ..- Source: s.l; s.n; 2002. 6 p. ilus, graf. Descriptors: MYCOBACTERIUM LEPRAE MYCOBACTERIUM LEPRAE MYCOBACTERIUM LEPRAE MONOCITOS ANTIGENOS DE BACTÉRIAS ANTIGENOS DE BACTÉRIAS ANTIGENOS DE BACTÉRIAS PROTEINAS DE BACTÉRIAS PROTEINAS DE BACTÉRIAS PROTEINAS DE BACTÉRIAS CLONAGEM MOLECULAR ESCHERICHIA COLI EXPRESSAO GENICA GENES BACTERIANOS INTERLEUCINA-12 PESO MOLECULAR ANALISE SEQUENCIAL PRECURSORES DE PROTEINAS PRECURSORES DE PROTEINAS PRECURSORES DE PROTEINAS Location: BR191.1; 08605/s

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Id: 11707 Author: Spencer, John S; Marques, Maria Angela M; Lima, Monica C. B. S; Junqueira-Kipnis, Ana Paula; Gregory, Bruce C; Truman, Richard W; Brennan, Patrick J Title: Antigenic specificity of the Mycobacterium leprae homologue of ESAT-6 ..- Source: s.l; s.n; 2002. 4 p. tab, graf. Descriptors: HANSENIASE MYCOBACTERIUM LEPRAE MYCOBACTERIUM LEPRAE MYCOBACTERIUM TUBERCULOSIS SEQUENCIA DE AMINOACIDOS ESPECIFICIDADE DE ANTICORPOS ANTIGENOS DE BACTÉRIAS ANTIGENOS DE BACTÉRIAS ANTIGENOS DE BACTÉRIAS ANTIGENOS DE BACTÉRIAS CLONAGEM MOLECULAR EPITOPOS DE LINFOCITO B EPITOPOS DE LINFOCITO B EPITOPOS DE LINFOCITO T EPITOPOS DE LINFOCITO T PROTEINAS RECOMBINANTES DE FUSAO PROTEINAS RECOMBINANTES DE FUSAO PROTEINAS RECOMBINANTES DE FUSAO HOMOLOGIA DE SEQUENCIA DE AMINOACIDOS FRAÇOES SUBCELULARES Location: BR191.1; 08457/s

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Id: 11686 Author: Ohara, Naoya; Matsuoka, Masanori; Nomaguchi, Hiroko; Naito, Mariko; Yamada, Takeshi Title: Protective responses against experimental Mycobacterium leprae infection in mice induced by recombinant Bacillus Calmette-Guérin over-producing three putative protective antigen candidates ..- Source: s.l; s.n; 2001. 5 p. ilus, graf. Descriptors: MYCOBACTERIUM LEPRAE MYCOBACTERIUM LEPRAE MYCOBACTERIUM LEPRAE MYCOBACTERIUM BOVIS MYCOBACTERIUM BOVIS HANSENIASE HANSENIASE ANTIGENOS DE BACTÉRIAS VACINA BCG VACINA BCG VACINA BCG SEQUENCIA DE BASES PRIMERS DO DNA CAMUNDONGOS ENDOGAMICOS BALB C CAMUNDONGOS ENDOGAMICOS C57BL PLASMIDEOS BAÇO Limits: ANIMAL MASCULINO CAMUNDONGOS Location: BR191.1; 08478/s

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Id: 11594 Author: Martin, E; Roche, P. W; Triccas, J. A; Britton, W. J Title: DNA encoding a single mycobacterial antigen protects against leprosy infection ..- Source: s.l; s.n; 2001. 6 p. tab. Descriptors: ANTIGENOS DE BACTÉRIAS VACINA BCG VACINAS BACTERIANAS VACINAS BACTERIANAS VACINAS BACTERIANAS SEQUENCIA DE BASES PRIMERS DO DNA DNA BACTERIANO DNA BACTERIANO INTERFERON TIPO II HANSENIASE HANSENIASE HANSENIASE CAMUNDONGOS MYCOBACTERIUM LEPRAE MYCOBACTERIUM LEPRAE LINFOCITOS T VACINAS DE DNA/GE/IM/*PD Limits: ANIMAL Location: BR191.1; 08417/s

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Id: 11472 Author: Dockrell, Hazel M; Brahmbhatt, Shweta; Robertson, Brian D; Britton, Sven; Fruth, Uli; Gebre, Negussie; Hunegnaw, Mesfin; Hussain, Rabia; Manandhar, Rakesh; Murillo, Luis; Pessolani, Maria Cristina V; Roche, Paul; Salgado, Jorge L; Sampaio, Elizabeth; Shahid, Firdaus; Thole, Jelle E. R; Young, Douglas B Title: A postgenomic approach to identification of mycobacterium leprae-specific peptides as T-cell reagents ..- Source: s.l; s.n; 2000. 10 p. tab, graf. Descriptors: HANSENIASE TUBERCULOIDE HANSENIASE TUBERCULOIDE HANSENIASE TUBERCULOIDE MYCOBACTERIUM LEPRAE MYCOBACTERIUM LEPRAE MYCOBACTERIUM LEPRAE SEQUENCIA DE AMINOACIDOS ANTIGENOS DE BACTÉRIAS ANTIGENOS DE BACTÉRIAS EPITOPOS DE LINFOCITO T EPITOPOS DE LINFOCITO T GENOMA BACTERIANO ANTIGENOS HLA-DR ANTIGENOS HLA-DR TRANSFORMAÇAO LINFOCITICA DADOS DE SEQUENCIA MOLECULAR PEPTIDIOS PEPTIDIOS ESPECIFICIDADE DE ESPÉCIES LINFOCITOS T Location: BR191.1; 08351/s

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Id: 10965 Author: El-Zaatari, Fouad A. K; Naser, Saleh A; Hulten, Kristina; Burch, Paula; Graham, David Y Title: Characterization of mycobacterium paratuberculosis p36 antigen and its seroreactivities in Crohn's diseases ..- Source: s.l; s.n; 1999. 5 p. ilus, tab. Descriptors: HANSENIASE MYCOBACTERIUM PARATUBERCULOSIS ANTICORPOS ANTIBACTÉRIAS ANTIGENOS DE BACTÉRIAS ANTIGENOS DE BACTÉRIAS ANTIGENOS DE BACTÉRIAS DOENÇA DE CROHN DNA BACTERIANO ELETROFORESE EM GEL DE POLIACRILAMIDA IMMUNOBLOTTING PROTEINAS RECOMBINANTES ANALISE DE SEQUENCIA DE DNA TUBERCULOSE Location: BR191.1; 07428/s

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Id: 10183 Author: Kaur, Gurvinder; Sachdeva, Geetanjali; Bhutani, L. K; Bamezai, R Title: Association of polimorphism at COL3A and CTLA4 loci on chromosome 2q31-33 with the clinical phenotype and in-vitro CMI status in healthy and leprosy subjects: a preliminary study ..- Source: s.l; s.n; 1997. 8 p. ilus, tab. Descriptors: HANSENIASE HANSENIASE HANSENIASE DIMORFA HANSENIASE DIMORFA HANSENIASE LEPROMATOSA HANSENIASE LEPROMATOSA HANSENIASE TUBERCULOIDE HANSENIASE TUBERCULOIDE ALELOS ANTIGENOS DE BACTÉRIAS ANTIGENOS DE DIFERENCIAÇAO CROMOSSOMOS HUMANOS PAR 2 HOMOZIGOTO IMUNIDADE CELULAR TRANSFORMAÇAO LINFOCITICA DADOS DE SEQUENCIA MOLECULAR MYCOBACTERIUM LEPRAE FENOTIPO REAÇAO EM CADEIA POR POLIMERASE POLIMORFISMO (GENÉTICA) PROCOLAGENO Location: BR191.1; 07096/s

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Id: 10094 Author: Winter, Nathalie; Triccas, James A; Rivoire, Becky; Pessolani, Maria Cristina V; Eiglmeier, Karin; Lim, Eng-Mong; Hunter, Shirley W; Brennan, Patrick J; Britton, Warwick J Title: Characterization of the gene encoding the immunodominant 35 kDa protein of Mycobacterium leprae ..- Source: s.l; s.n; 1995. 12 p. ilus, tab, graf. Descriptors: HANSENIASE MYCOBACTERIUM MYCOBACTERIUM MYCOBACTERIUM LEPRAE SEQUENCIA DE AMINOACIDOS ANTICORPOS MONOCLONAIS ANTIGENOS DE BACTÉRIAS ANTIGENOS DE BACTÉRIAS ANTIGENOS DE BACTÉRIAS SEQUENCIA DE BASES COSMIDIOS PRIMERS DO DNA BIBLIOTECA DE GENES GENES BACTERIANOS GENES DOMINANTES DADOS DE SEQUENCIA MOLECULAR PESO MOLECULAR REAÇAO EM CADEIA POR POLIMERASE REGIOES PROMOTORAS (GENÉTICA) PROTEINAS RECOMBINANTES MAPEAMENTO POR RESTRIÇAO HOMOLOGIA DE SEQUENCIA DE AMINOACIDOS LINFOCITOS T Location: BR191.1; 07153/s

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Id: 10093 Author: Deshpande, Rajashri G; Khan, Mahfuz B; Bhat, Deepashree A; Navalkar, R. G Title: Immunoaffinity chromatographic isolation of a high molecular weight seroreactive protein from Mycobacterium leprae cell sonicate ..- Source: s.l; s.n; 1995. 7 p. ilus, tab. Descriptors: HANSENIASE MYCOBACTERIUM LEPRAE MYCOBACTERIUM LEPRAE MYCOBACTERIUM LEPRAE MYCOBACTERIUM PARATUBERCULOSIS ANTICORPOS MONOCLONAIS ANTIGENOS DE BACTÉRIAS ANTIGENOS DE BACTÉRIAS ANTIGENOS DE BACTÉRIAS PROTEINAS DE BACTÉRIAS PROTEINAS DE BACTÉRIAS PROTEINAS DE BACTÉRIAS CITOCROMO B FERRITINA DADOS DE SEQUENCIA MOLECULAR PESO MOLECULAR HOMOLOGIA DE SEQUENCIA DE AMINOACIDOS Limits: ANIMAL HUMANO COELHOS Location: BR191.1; 07152/s

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Id: 9866 Author: Bigi, Fabiana; Alito, Alicia; Fisanotti, Juan Carlos; Romano, Maria Isabel; Cataldi, Angel Title: Characterization of a novel Mycobacterium bovis secreated antigen containing PGLTS repeats ..- Source: s.l; s.n; 1995. 6 p. ilus. Descriptors: HANSENIASE MYCOBACTERIUM BOVIS SEQUENCIA DE AMINOACIDOS ANTIGENOS DE BACTÉRIAS CLONAGEM MOLECULAR DNA BACTERIANO GENES ESTRUTURAIS BACTERIANOS DADOS DE SEQUENCIA MOLECULAR MAPEAMENTO POR RESTRIÇAO ALINHAMENTO DE SEQUENCIA HOMOLOGIA DE SEQUENCIA DE AMINOACIDOS Location: BR191.1; 06811/s

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Id: 9731 Author: Sela, S; Thole, J. E. R; Ottenhoff, Tom H. M; Clark-Curtiss, J. E Title: Identification of mycobacterium leprae antigens from a cosmid library: characterization of a 15-kilodalton antigen that is recognized by both the humoral and cellular immune systems in leprosy patients ..- Source: s.l; s.n; 1991. 8 p. ilus, tab, graf. Descriptors: SEQUENCIA DE AMINOACIDOS ANTICORPOS ANTIBACTÉRIAS ANTIGENOS DE BACTÉRIAS ANTIGENOS DE BACTÉRIAS SEQUENCIA DE BASES WESTERN BLOTTING DNA BACTERIANO BIBLIOTECA GENOMICA HANSENIASE HANSENIASE TUBERCULOIDE TRANSFORMAÇAO LINFOCITICA DADOS DE SEQUENCIA MOLECULAR PESO MOLECULAR MYCOBACTERIUM LEPRAE MYCOBACTERIUM LEPRAE HIBRIDIZAÇAO DE ACIDO NUCLÉICO OLIGONUCLEOTIDIOS HOMOLOGIA DE SEQUENCIA DO ACIDO NUCLÉICO FASES DE LEITURA REAÇAO EM CADEIA POR POLIMERASE MAPEAMENTO POR RESTRIÇAO Location: BR191.1; 06530/s

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Id: 9697 Author: Rinke de Wit, Tobias F; Clark-Curtiss, Josephine E; Abebe, Feseha; Kolk, Arend H. J; Janson, Anneke A. M; Van Agterveld, Miranda; Thole, Jelle E. R Title: A Mycobacterium leprae-specific gene enconding an immunological recognized 45 kDa protein ..- Source: s.l; s.n; 1993. 10 p. ilus, tab. Descriptors: HANSENIASE DIMORFA HANSENIASE LEPROMATOSA MYCOBACTERIUM LEPRAE MYCOBACTERIUM LEPRAE MYCOBACTERIUM TUBERCULOSIS MYCOBACTERIUM TUBERCULOSIS SEQUENCIA DE AMINOACIDOS ANTICORPOS ANTIBACTÉRIAS ANTIGENOS DE BACTÉRIAS ANTIGENOS DE BACTÉRIAS PROTEINAS DE BACTÉRIAS PROTEINAS DE BACTÉRIAS PROTEINAS DE BACTÉRIAS SEQUENCIA DE BASES CLONAGEM MOLECULAR DNA BACTERIANO GENES BACTERIANOS FERTILIZAÇAO IN VITRO DADOS DE SEQUENCIA MOLECULAR PESO MOLECULAR LINFOCITOS T Location: BR191.1; 06653/s

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Id: 9492 Author: Mckenzie, Kirsten R; Adams, Elizabeth; Britton, Warwick J; Garsia, Roger J; Basten, Antony Title: Sequence and immunogenicity of the 70-kDa heat shock protein of Mycobacterium leprae ..- Source: s.l; s.n; 1991. 8 p. ilus, graf. Descriptors: SEQUENCIA DE AMINOACIDOS ANTIGENOS DE BACTÉRIAS ANTIGENOS DE BACTÉRIAS PROTEINAS DE BACTÉRIAS PROTEINAS DE BACTÉRIAS SEQUENCIA DE BASES CLONAGEM MOLECULAR DNA BACTERIANO GENES ESTRUTURAIS BACTERIANOS PROTEINAS DO CHOQUE TÉRMICO PROTEINAS DO CHOQUE TÉRMICO TRANSFORMAÇAO LINFOCITICA DADOS DE SEQUENCIA MOLECULAR MYCOBACTERIUM LEPRAE MYCOBACTERIUM LEPRAE MAPEAMENTO POR RESTRIÇAO Limits: IN VITRO Location: BR191.1; 06348/s

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Id: 9455 Author: Laal, Suman; Sharma, Y. D; Prasad, H. K; Murtaza, Anwar; Singh, Satish; Tangri, Shabnam; Misra, Radhey; Nath, Indira Title: Recombinant fusion protein identified by lepromatous sera mimics native Mycobacterium leprae in T-cell responses across the leprosy spectrum ..- Source: s.l; s.n; 1991. 5 p. ilus, tab, graf. Descriptors: SEQUENCIA DE AMINOACIDOS ANTICORPOS MONOCLONAIS ESPECIFICIDADE DE ANTICORPOS COMPLEXO ANTIGENO-ANTICORPO ANTIGENOS DE BACTÉRIAS ANTIGENOS DE BACTÉRIAS SEQUENCIA DE BASES BIBLIOTECA DE GENES SOROS IMUNES IMMUNOBLOTTING HANSENIASE HANSENIASE LEPROMATOSA TRANSFORMAÇAO LINFOCITICA DADOS DE SEQUENCIA MOLECULAR MYCOBACTERIUM LEPRAE MYCOBACTERIUM LEPRAE PROTEINAS RECOMBINANTES DE FUSAO PROTEINAS RECOMBINANTES DE FUSAO VALORES DE REFERENCIA MAPEAMENTO POR RESTRIÇAO LINFOCITOS T Location: BR191.1; 06305/s

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Id: 9336 Author: Mehra, Vijay; Bloom, Barry R; Bajardi, Adriana C; Grisso, Cara L; Sieling, Peter A; Alland, David; Convit, Jacinto; Fan, Xuedong; Hunter, Shirley W; Brennan, Patrick J; Rea, Thomas H; Modlin, Robert L Title: A major T cell antigen of Mycobacterium leprae is a 10-kD heat-shock cognate protein ..- Source: s.l; s.n; 1992. 10 p. ilus, graf. Descriptors: SEQUENCIA DE AMINOACIDOS ANTIGENOS DE BACTÉRIAS ANTIGENOS DE BACTÉRIAS ANTIGENOS DE BACTÉRIAS TATUS WESTERN BLOTTING CLONAGEM MOLECULAR DNA BACTERIANO DNA BACTERIANO BIBLIOTECA DE GENES GENES BACTERIANOS PROTEINAS DO CHOQUE TÉRMICO PROTEINAS DO CHOQUE TÉRMICO PROTEINAS DO CHOQUE TÉRMICO HANSENIASE DADOS DE SEQUENCIA MOLECULAR PESO MOLECULAR MYCOBACTERIUM LEPRAE MYCOBACTERIUM LEPRAE PROTEINAS RECOMBINANTES PROTEINAS RECOMBINANTES MAPEAMENTO POR RESTRIÇAO HOMOLOGIA DE SEQUENCIA DO ACIDO NUCLÉICO LINFOCITOS T Limits: ANIMAL ESTUDO COMPARATIVO Location: BR191.1; 06466/s

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