Database : HANSEN Search on : CELULAS INTERSTICIAIS DO TESTICULO/CITOL [Subject descriptor] References found : 2 [refine] Displaying: 1 .. 2   in format [Detailed]

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Id: 19471 Author: Ishikawa, Satoshi; Mizushima, Mutsue; Furuta, Mutsuhiro; Ishikawa, Asako; Kawamura, Kenji. Title: Leydig cell hyperplasia and the maintenance of bone volume: bone histomorphometry and testicular histopathology in 29 male leprosy autopsy cases. Source: Int. J. Lepr;68(3):258-266, Sept., 2000. ilus, tab. Abstract: This study was conducted to determine if osteoporosis in male leprosy patients is caused by testicular atrophy. Bone volume (BV/TV), trabecular number (TbN), trabecular thickness (TbTh), and trabecular separation (TbSp) were measured in two areas in decalcified paraffin sections of lumbar bones from 29 male leprosy and 6 male nonleprosy autopsy cases. We found significant differences in the average BV/TV measurements among the 7 patients with nodular Leydig cell hyperplasia (BV/TV 12.24%) and the 22 patients without hyperplasia (BV/TV 7.35%) and 6 patients without leprosy (BV/TV 12.98%). Bone volume was maintained in patients with nodular Leydig cell hyperplasia, and we determined no clinical factor other than the Leydig cell hyperplasia that reflected the bone volume. The osteoporosis of male leprosy patients was attributed to secondary gonadal dysfunction due to testicular atrophy, and Leydig cell hyperplasia appears to preserve bone volume. (AU)^ien. Descriptors: Células Intersticiais do Testículo/fisiol Tumor de Células de Leydig/fisiopatol Células Intersticiais do Testículo/citol Hanseníase/compl Limits: Humanos Electronic Medium: http://hansen.bvs.ilsl.br/textoc/revistas/intjlepr/2000/pdf/v68n3/v68n3a02.pdf / en Location: BR191.1

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Id: 13237 Author: Kumar B;; Raina, A; Kaur, S; Dash, R. J; Samuel, E; Datta, B. N Title: Clinico-pathological study of testicular involvement in leprosy ..- Source: s.l; s.n; jan. 1982. 8 p. ilus. Abstract: Twenty five patients of lepromatous leprosy were studied clinically and histopathologically for testicular involvement. Testicular pain or swelling was the commonest complaint (68%) followed by sterility (28%) and impotence (4%). Reduced testicular size associated with soft feel was observed in 76% patients. Gynaecomastia was present in 36% and altered sexual hair pattern in 24%. Eleven out of sixteen (69%) patients had oligo/azoospermia. Out of the twenty testicular biopsies 15 (75%) had definite histological evidence of leprous pathology, irrespective of testicular size, semen picture and clinical signs and symptoms. One out of three epididymal biopsies showed minimal changes. Histopathological changes varied markedly, it was not possible to categorize these into vascular, interstitial and obliterative phases.(AU). Descriptors: HANSENIASE/compl HANSENIASE/imunol HANSENIASE/patol ATROFIA CELULAS INTERSTICIAIS DO TESTICULO/patol ORQUITE/etiol ORQUITE/imunol ORQUITE/patol TUBULOS SEMINIFEROS/patol TESTICULO/patol Limits: HUMANO MASCULINO ADULTO MEIA-IDADE IDOSO ADOLESCENTE Electronic Medium: http://www.ilsl.br Location: BR191.1; 02145/s

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