Database : HANSEN
Search on : HIPOGONADISMO [Subject descriptor]
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Id:13492
Author:Kannan, V; Vijaya, G
Title:Endocrine testicular functions in leprosy ..-
Source:s.l; s.n; mar. 1984. 5 p. tab.
Abstract:Pituitary testicular functions were evaluated in leprosy. Forty-three men with leprosy were studied by basal estimations of plasma LH, FSH, Prolactin, Testosterone, 17-beta estradiol, metoclopramide stimulated prolactin responses and hCG stimulated testosterone responses. Fifteen young healthy men with proven fertility were studied as control subjects. The hormone estimations were related to the histologic changes observed in the testicular biopsies of leprous hypogonadism. In lepromatous leprosy (n:18) the basal plasma gonadotropin levels were significantly increased (FSH 29.5 +/- 2.3 mlU/ml; LH 21.5 +/- 1.9 mlU/ml, mean +/- SE). The plasma gonadotropins were in the normal range in tuberculoid leprosy. In borderline leprosy, the basal mean plasma FSH was normal, whereas LH levels were significantly increased (22.5 +/- 1.2 mlU/ml). The basal plasma testosterone levels were significantly decreased in lepromatous leprosy (1.6 +/- 0.12 ng/ml), tuberculoid leprosy (4.2 +/- 1.7 ng/ml) and borderline leprosy (1.8 +/- 0.18 ng/ml). The basal plasma 17-beta estradiol levels were significantly elevated in all the three types of leprosy. The basal plasma prolactin levels in plasma were significantly increased in lepromatous and tuberculoid leprosy. During hCG stimulation tests, the peak plasma testosterone responses were significantly reduced in both lepromatous leprosy and tuberculoid leprosy subjects. The blunted testosterone responses during hCG stimulation tests in leprosy correlated with the high basal 17-beta estradiol levels (r = 0.58; P less than 0.05). These results strongly suggest that hypogonadism in leprosy results from primary testicular failure. The significant elevation of plasma 17-beta estradiol levels in lepromatous, tuberculoid and borderline leprosy could play a role in hypogonadism of leprosy.(AU).
Descriptors:METOCLOPRAMIDA/uso diag
HIPOGONADISMO/sangue
HIPOGONADISMO/etiol
HANSENIASE/sangue
HANSENIASE/compl
HANSENIASE/etiol
HORMÔNIO FOLICULO ESTIMULANTE/sangue
ESTRADIOL/sangue
HORMÔNIOS/sangue
GONADOTROPINAS/uso diag
Limits:HUMANO
MASCULINO
ADULTO
MEIA-IDADE
Electronic Medium:http://www.ilsl.br
Location:BR191.1; 01616/s


  2 / 4 HANSEN  
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Id:13375
Author:Faulstich, M. E
Title:Behavioral analysis of sexual dysfunction in Hansen's disease ..-
Source:s.l; s.n; feb. 1985. 4 p. .
Abstract:Human sexual behavior is an interactive process including CNS, hormonal, and sex-gland activities. This process can be disrupted in males who have Hansen's disease if testicular atrophy occurs. Elevations of centrally mediated luteinizing hormone and deficient testosterone levels were found in a male with Hansen's disease whose insufficient erections were secondary to atrophic testes. Quasi-experimental (A-B) analysis provided evidence for the efficacy of testosterone treatment for such a condition.(AU).
Descriptors:HIPOGONADISMO/etiol
HANSENIASE/compl
PÊNIS/fisiopatol
TRANSTORNOS SEXUAIS/quimioter
TRANSTORNOS SEXUAIS/etiol
TRANSTORNOS SEXUAIS/fisiopatol
TESTOSTERONA/uso terap
Limits:RELATO DE CASO
HUMANO
MASCULINO
FEMININO
ADULTO
Electronic Medium:http://www.ilsl.br
Location:BR191.1; 01566/s


  3 / 4 HANSEN  
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Id:8288
Author:Leal, Angela M. O
Title:Alteracoes endocrinas na hanseniase Endocrine changes in leprosy-
Source:Ribeirao Preto; s.n; 1997. 5 p. .
Descriptors:HANSENIASE
HIPOGONADISMO
HORMONIOS
Location:BR191.1; 05984/s


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Id:3760
Author:Faulstich, Michael E
Title:Behavioral analysis of sexual dysfunction in Hansen's disease ..-
Source:s.l; s.n; 1985. 4 p. .
Descriptors:HANSENIASE
HIPOGONADISMO
PENIS
PENIS
TRANSTORNOS SEXUAIS
TRANSTORNOS SEXUAIS
TRANSTORNOS SEXUAIS
TESTOSTERONA
Limits:ADULTO
Location:BR191.1; 02599/s



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