Database : HANSEN Search on : MYCOBACTERIUM LEPRAE/ENZIMOL [Subject descriptor] References found : 6 [refine] Displaying: 1 .. 6   in format [Detailed]

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Id: 13275 Author: Prabhakaran, K; Harris, E. B; Kirchheimer, W. F Title: A possible method for improving the efficacy of dapsone ..- Source: s.l; s.n; December 15, 1980. 2 p. tab. Abstract: The antileprosy drug dapsone is unable to penetrate intact Mycobacterium leprae in vitro, as determined by its effect on o-diphenoloxidase in the bacilli. When combined with the peptide polylysine, the sulfone drug passes through the bacterial cell membranes, and penetrates the enzyme protein, resulting in a 100% inhibition of its activity. Descriptors: CATECOL OXIDASE/antag PERMEABILIDADE DA MEMBRANA CELULAR/ef drogas COMBINACAO DE MEDICAMENTOS CONCENTRACAO DE IONS DE HIDROGÊNIO MYCOBACTERIUM LEPRAE/enzimol PEPTIDIOS/uso terap DAPSONA/admin DAPSONA/farmacol POLILISINA/farmacol POLILISINA/uso terap Electronic Medium: http://www.ilsl.br Location: BR191.1; 00684/s

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Id: 13259 Author: Wheeler, P. R; Gregory, D Title: Superoxide dismutase, peroxidatic activity and catalase in Mycobacterium leprae purified from armadillo liver ..- Source: s.l; s.n; dec. 1980. 8 p. graf. Abstract: Superoxide dismutase has been identified and peroxidatic activity demonstrated in Mycobacterium leprae. The superoxide dismutase, shown indirectly to be a manganese-containing enzyme, was present at low activity in the cell-free extract. Peroxidatic activity was detected in a haemoprotein on polyacrylamide gels, but quantitative assay was not possible. Catalase, although present in a cell-free extract, appeared to be a host-derived enzyme, thus emphasizing the importance of establishing the authenticity of enzyme activities in host-derived M. leprae. The implications for the growth of M. leprae in vivo and its non-cultivability are discussed in the light of these findings.(AU). Descriptors: TATUS/metab CATALASE/metab FIGADO/enzimol FIGADO/microbiol MYCOBACTERIUM LEPRAE/enzimol MYCOBACTERIUM LEPRAE/isol PEROXIDOS/metab SUPEROXIDO DISMUTASE/metab HIDROXIDO DE SÓDIO/farmacol Limits: ANIMAL Electronic Medium: http://www.ilsl.br Location: BR191.1; 00755/s

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Id: 10970 Author: Kai, Masanori; Matsuoka, Masanori; Nakata, Noboru; Maeda, Shinji; Gidoh, Masaichi; Maeda, Yumi; Hashimoto, Ken; Kobayashi, Kazuo; Kashiwabara, Yoshiko Title: Diaminodiphenylsulfone resistance of mycobacterium leprae due to mutations in the dihydropteroate synthase gene ..- Source: s.l; s.n; 1999. 5 p. tab. Descriptors: HANSENIASE LEPROSTATICOS MYCOBACTERIUM LEPRAE MYCOBACTERIUM LEPRAE MYCOBACTERIUM LEPRAE DAPSONA DIIDROPTEROATO SINTASE RESISTENCIA MICROBIANA A DROGAS GENES BACTERIANOS DADOS DE SEQUENCIA MOLECULAR MUTAÇAO Location: BR191.1; 07334/s

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Id: 9869 Author: Bisht, Deepa; Mehrotra,, Jyoti; Dhindsa, M. S; Singh, N. B; Sinha, Sudhir Title: A major T-cell-inducing cytosolic 23 kDa protein antigen of the vaccine candidate Mycobacterium habana is superoxide dismutase ..- Source: s.l; s.n; 1996. 9 p. ilus, tab. Descriptors: MYCOBACTERIUM LEPRAE SEQUENCIA DE AMINOACIDOS ANTIGENOS DE BACTÉRIAS ANTIGENOS DE BACTÉRIAS PROTEINAS DE BACTÉRIAS PROTEINAS DE BACTÉRIAS VACINAS BACTERIANAS HANSENIASE TUBERCULOIDE TRANSFORMAÇAO LINFOCITICA CAMUNDONGOS ENDOGAMICOS BALB C DADOS DE SEQUENCIA MOLECULAR PESO MOLECULAR FITOHEMAGLUTININAS SUPEROXIDO DISMUTASE SUPEROXIDO DISMUTASE LINFOCITOS T Location: BR191.1; 06808/s

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Id: 6837 Author: Manalang, J Title: Non-acid-fast forms of MY. leprae in leprotic lesions: preliminary report ..- Source: s.l; s.n; 1938. 5 p. tab. Descriptors: HANSENIASE HANSENIASE - MYCOBACTERIUM LEPRAE  MYCOBACTERIUM LEPRAE Location: BR191.1; 05136/s

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Id: 3869 Author: Wheeler, P. R Title: Catabolic pathways for glucose, glycerol and 6-phosphogluconate in Mycobacterium leprae grown in armadillo tissues ..- Source: s.l; s.n; 1983. 14 p. ilus, tab. Descriptors: MYCOBACTERIUM LEPRAE MYCOBACTERIUM LEPRAE TATUS ELETROFORESE EM GEL DE POLIACRILAMIDA GLUCONATOS GLICERINA GLUCOSE Location: BR191.1; 02705/s

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