Database : HANSEN Search on : ANTIGENOS DE DIFERENCIACAO DE LINFOCITOS B/SANGUE [Subject descriptor] References found : 9 [refine] Displaying: 1 .. 9   in format [Detailed]

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Id: 18286 Author: Reinherz, Ellis L; Schlossman, Stuart F Title: The differentiation and function of human T lymphocytes ..- Source: s.l; s.n; 1980. 7 p. tab, graf. Descriptors: ANTIGENOS DE DIFERENCIACAO DE LINFOCITOS B/anal ANTIGENOS DE DIFERENCIACAO DE LINFOCITOS B/sangue ANTIGENOS DE DIFERENCIACAO DE LINFOCITOS B/imunol ANTIGENOS DE DIFERENCIACAO DE LINFOCITOS T/anal ANTIGENOS DE DIFERENCIACAO DE LINFOCITOS T/sangue ANTIGENOS DE DIFERENCIACAO DE LINFOCITOS T/imunol ANTIGENOS SECUNDARIOS DE ESTIMULACAO DE LINFOCITOS/anal ANTIGENOS SECUNDARIOS DE ESTIMULACAO DE LINFOCITOS/sangue ANTIGENOS SECUNDARIOS DE ESTIMULACAO DE LINFOCITOS/imunol LINFOCITOS/sangue LINFOCITOS/clas LINFOCITOS/imunol - INTERLEUCINA-1/anal  INTERLEUCINA-1/sangue  INTERLEUCINA-1/imunol  ANTICORPOS MONOCLONAIS/bios  ANTICORPOS MONOCLONAIS/isol  ANTICORPOS MONOCLONAIS/farmacocin  IMUNOFLUORESCÊNCIA/util Limits: HUMANO ANIMAL Location: BR191.1; 00799/s

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Id: 13727 Author: Cheadle, Eleanor J; Selby, Peter J; Jackson, Andrew M Title: Mycobacterium bovis bacillus Calmette-Guérin-infected dendritic cells potently activate autologous T cells via a B7 and interleukin-12-dependent mechanism ..- Source: s.l; s.n; 2003. 10 p. graf. Abstract: Mycobacteria are potent adjuvants, can survive intracellularly and have been safely used for many years as vaccines against tuberculosis and leprosy. They are thus important potential vectors for recombinant vaccines. Many of their adjuvant properties are mediated following phagocytosis by dendritic cells (DC), which are in turn critical for priming naïve T cells. Although the maturation of DC in response to mycobacteria, such as Mycobacterium bovis bacillus Calmette-Guérin (BCG), is well described the subsequent responses of autologous T cells to mycobacterium-infected DC remains uncharacterized. In our experiments DC infected with BCG expressed more co-stimulatory molecules than tumour-necrosis factor-alpha (TNF-alpha) -treated DC and stimulated more potent mixed leucocyte reactions. When autologous T cells were co-cultured with BCG-exposed DC they became highly activated, as determined by display of CD25, CD54 and CD71 on both CD4+ and CD8+ cells. In contrast, the response of T cells to TNF-alpha-matured DC was significantly less. Cytokine production from T cells cultured with BCG-exposed DC was enhanced with elevated secretion of interleukin-2 (IL-2), IL-10 and interferon-gamma (IFN-gamma) and was produced by both CD4+ and CD8+ lymphocytes as determined by intracellular staining. In particular, IFN-gamma secretion was increased from 50 pg/ml to 25 000 pg/ml and IL-10 secretion increased from 20 pg/ml to 300 pg/ml in BCG-exposed DC co-cultures. Blocking antibodies to B7.1 and B7.2 or IL-12 significantly reduced the secretion of IFN-gamma and reductions were also seen in the expression of CD25 and CD71 by CD4+ cells. These data demonstrate that mycobacterially infected DC are particularly potent activators of autologous T cells compared to TNF-alpha-exposed DC and that the resultant T cells are functionally superior. (AU). Descriptors: ANTIGENOS CD/metab ANTIGENOS CD80/imunol ANTIGENOS DE DIFERENCIACAO DE LINFOCITOS B/metab LINFOCITOS T CD4-POSITIVOS/imunol LINFOCITOS T CD8-POSITIVOS/imunol CITOCINAS/bios CELULAS DENDRITICAS/imunol CELULAS DENDRITICAS/microbiol MOLECULA 1 DE ADESAO INTERCELULAR IMUNOFENOTIPAGEM INTERLEUCINA-12/imunol TRANSFORMACAO LINFOCITICA/imunol MYCOBACTERIUM BOVIS/imunol RECEPTORES DA INTERLEUCINA-2/metab LINFOCITOS T/imunol FATOR DE NECROSE TUMORAL/imunol REGULACAO PARA CIMA/imunol Limits: HUMANO SUPPORT, NON-U.S. GOV'T Electronic Medium: http://www.ilsl.br Location: BR191.1; 08996/s

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Id: 12228 Author: Mustafa, T; Bjune, G; Jonsson, R; Pando, R. H.; Nilsen, R Title: Increased expression of fas ligand in human tuberculosis and leprosy lesions: a potential novel mechanism of immune evasion in mycobacterial infection ..- Source: s.l; s.n; 2001. 10 p. ilus, tab, graf. Descriptors: ANTIGENOS DE BACTÉRIAS ANTIGENOS CD ANTIGENOS CD95 ANTIGENOS DE DIFERENCIAÇAO MIELOMONOCITICA APOPTOSE GRANULOMA DE CORPO ESTRANHO GRANULOMA DE CORPO ESTRANHO IMUNOHISTOQUIMICA LEISHMANIOSE CUTANEA LEISHMANIOSE CUTANEA HANSENIASE HANSENIASE HANSENIASE GLICOPROTEINAS DE MEMBRANAS MODELOS IMUNOLOGICOS MYCOBACTERIUM LEPRAE MYCOBACTERIUM TUBERCULOSIS TUBERCULOSE TUBERCULOSE TUBERCULOSE Location: BR191.1; 08711/s

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Id: 12122 Author: Ochoa, Maria Teresa; Stenger, Steffer; Sieling, Peter A; Thoma-Uszynski, Sybille; Sabet, Shereen; Cho, Sungae; Krensky, Alan M; Rollinghoff, Martin; Sarno, Euzenir Nunes; Burdick, Anne E; Rea, Thomas H; Modlin, Robert L Title: T-cell release of granulysin contributes to host defense in leprosy ..- Source: s.l; s.n; feb. 2001. 6 p. ilus, graf. Descriptors: ANTIINFECCIOSOS ANTIGENOS CD3 ANTIGENOS DE DIFERENCIAÇAO DE LINFOCITOS T ANTIGENOS DE DIFERENCIAÇAO DE LINFOCITOS T LINFOCITOS T CD4-POSITIVOS HANSENIASE LEPROMATOSA HANSENIASE LEPROMATOSA HANSENIASE TUBERCULOIDE HANSENIASE TUBERCULOIDE Células Cultivadas Location: BR191.1; 08698/s

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Id: 11685 Author: Ochoa, Maria-Teresa; Stenger, Steffen; Sieling, Peter A; Thoma-Uszynski, Sybille; Sabet, Shereen; Cho, Sungae; Krensky, Alan M; Rollinghoff, Martin; Sarno, Euzenir Nunes; Burdick, Anne E; Rea, Thomas H; Modlin, Robert L Title: T-cell release of granulysin contributes to host defense in leprosy ..- Source: s.l; s.n; 2001. 6 p. ilus, graf. Descriptors: HANSENIASE LEPROMATOSA HANSENIASE LEPROMATOSA HANSENIASE TUBERCULOIDE HANSENIASE TUBERCULOIDE ANTIINFECCIOSOS ANTIGENOS CD3 ANTIGENOS DE DIFERENCIAÇAO DE LINFOCITOS T ANTIGENOS DE DIFERENCIAÇAO DE LINFOCITOS T LINFOCITOS T CD4-POSITIVOS Location: BR191.1; 08477/s

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Id: 11001 Author: Schlienger, Katia; Uyemura, Koichi; Jullien, Denis; Sieling, Peter A; Rea, Thomas H; Linsley, Peter S; Modlin, Robert L Title: B7-1, but not CD28, is crucial for the maintenance of the CD4+ T cell responses in human leprosy ..- Source: s.l; s.n; 1998. 7 p. tab, graf. Descriptors: HANSENIASE LEPROMATOSA HANSENIASE LEPROMATOSA HANSENIASE TUBERCULOIDE HANSENIASE TUBERCULOIDE MYCOBACTERIUM LEPRAE ANTICORPOS BLOQUEADORES ANTIGENOS CD ANTIGENOS CD28 ANTIGENOS CD28 ANTIGENOS DE DIFERENCIAÇAO ANTIGENOS CD80 ANTIGENOS CD80 ANTIGENOS CD80 LINFOCITOS T CD4-POSITIVOS LINFOCITOS T CD4-POSITIVOS CÉLULAS CLONAIS SOROS IMUNES LEUCOCITOS MONONUCLEARES TRANSFORMAÇAO LINFOCITICA GLICOPROTEINAS DE MEMBRANAS TRANSDUÇAO DE SINAL PELE PELE Location: BR191.1; 07275/s

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Id: 10183 Author: Kaur, Gurvinder; Sachdeva, Geetanjali; Bhutani, L. K; Bamezai, R Title: Association of polimorphism at COL3A and CTLA4 loci on chromosome 2q31-33 with the clinical phenotype and in-vitro CMI status in healthy and leprosy subjects: a preliminary study ..- Source: s.l; s.n; 1997. 8 p. ilus, tab. Descriptors: HANSENIASE HANSENIASE HANSENIASE DIMORFA HANSENIASE DIMORFA HANSENIASE LEPROMATOSA HANSENIASE LEPROMATOSA HANSENIASE TUBERCULOIDE HANSENIASE TUBERCULOIDE ALELOS ANTIGENOS DE BACTÉRIAS ANTIGENOS DE DIFERENCIAÇAO CROMOSSOMOS HUMANOS PAR 2 HOMOZIGOTO IMUNIDADE CELULAR TRANSFORMAÇAO LINFOCITICA DADOS DE SEQUENCIA MOLECULAR MYCOBACTERIUM LEPRAE FENOTIPO REAÇAO EM CADEIA POR POLIMERASE POLIMORFISMO (GENÉTICA) PROCOLAGENO Location: BR191.1; 07096/s

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Id: 10086 Author: Cuevas-Santos, Jesus; Contreras, Felix; McNutt, N. Scott Title: Multibacillary leprosy: lesions with macrophages positive for S100 protein and dendritic cells positive for factor 13a ..- Source: s.l; s.n; 1998. 8 p. ilus, tab. Descriptors: HANSENIASE HANSENIASE HANSENIASE DIMORFA HANSENIASE DIMORFA HANSENIASE LEPROMATOSA HANSENIASE LEPROMATOSA HANSENIASE TUBERCULOIDE HANSENIASE TUBERCULOIDE ANTIGENOS CD ANTIGENOS CD1 ANTIGENOS DE DIFERENCIAÇAO ANTIGENOS DE DIFERENCIAÇAO MIELOMONOCITICA PROTEINA-GLUTAMINA GAMA-GLUTAMILTRANSFERASE Location: BR191.1; 07145/s

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Id: 9308 Author: Sullivan, Laura; Sano, Shigetoshi; Pirmez, Claude; Salgame, Padmini; Mueller, Christoph; Hofaman, Florence; Uyemura, Koichi; Rea, Thomas H; Bloom, Barry R; Modlin, Robert L Title: Expression of adhesion molecules in leprosy lesions ..- Source: s.l; s.n; 1991. 7 p. ilus, tab, graf. Descriptors: ANTIGENOS CD2 ANTIGENOS CD58 ANTIGENOS DE DIFERENCIAÇAO DE LINFOCITOS T ANTIGENOS DE SUPERFICIE MOLÉCULAS DE ADESAO CELULAR EPIDERME EPIDERME EXPRESSAO GENICA MOLÉCULA 1 DE ADESAO INTERCELULAR INTERFERON TIPO II HANSENIASE HANSENIASE HANSENIASE ANTIGENO-1 LINFOCITARIO ASSOCIADO A FUNÇAO HIBRIDIZAÇAO DE ACIDO NUCLÉICO RECEPTORES IMUNOLOGICOS LINFOCITOS T LINFOTOXINA Location: BR191.1; 06211/s

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