Database : HANSEN Search on : CROMATOGRAFIA [Subject descriptor] References found : 19 [refine] Displaying: 1 .. 19   in format [Detailed]

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Id: 17303 Author: Queiroz, R. H. C; Pereira, R. C; Gotardo, M. A; Cordeiro, D. S; Melchior, E Title: Determination of clofazimine in leprosy patients by high-performance liquid chromatography ..- Source: s.l; s.n; 2003. 4 p. ilus, tab. Abstract: An original, simple, specific, and rapid high-performance liquid chromatography assay for the determination of clofazimine in human plasma is presented. The procedure consists of extracting the drug and the internal standard (medazepam) from 0.5 mL plasma with dichloromethane/diisopropyl ether (1:1, v/v) at pH 3.0, after precipitating the proteins with methanol. The drugs were then quantitated on a reversed-phase C8 using a mobile phase consisting of a mixture of methanol/0.25 N sodium acetate buffer at pH 3.0 (74:26, v/v). The flow-rate and wavelength were set at 1 mL/min and 286 nm, respectively. The precision, linearity, and limit of quantitation of the method were within acceptable limits. The method was considered adequate and could be applied in studies involving blood level monitoring and pharmacokinetics in leprosy patients. (AU). Descriptors: Cromatografia Líquida de Alta Pressão/*MT Clofazimina/*PK/TU Monitoramento de Medicamentos/*MT Hansenostáticos/*PK/TU Hanseníase/DT/*ME Reprodutibilidade de Resultados Sensibilidade e Especificidade Limits: Feminino Humano Masculino Location: BR191.1; 01158/s

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Id: 13509 Author: Young, Douglas B Title: Identification of Mycobacterium leprae: use of wall-bound mycolic acids ..- Source: s.l; s.n; nov. 1980. 5 p. ilus. Abstract: A simple method for extraction and analysis of wall-bound mycolic acids from small samples of mycobacteria is described. Separation of mycolic acid classes according to their functional groups by thin-layer chromatography showed a difference between Mycobacterium leprae and a number of strains of acid-fast bacilli cultured from leprosy biopsies in vitro. This technique is proposed as a convenient preliminary test in the identification of possible cultures of M. leprae.(AU). Descriptors: PAREDE CELULAR CROMATOGRAFIA EM CAMADA DELGADA MYCOBACTERIUM LEPRAE/clas ACIDOS MICOLICOS/isol Limits: SUPPORT, NON-U.S. GOV'T Electronic Medium: http://www.ilsl.br Location: BR191.1; 00360/s

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Id: 11616 Author: Teo, S. K; Sabourin, P. J; O'Brien, K; Kook, K. A; Thomas, S. D Title: Metabolism of thalidomide in human microsomes, cloned human cytochrome P-450 isozymes, and Hansen's disease patients ..- Source: s.l; s.n; 2000. 8 p. ilus, tab, graf. Descriptors: HANSENIASE CROMATOGRAFIA LIQUIDA DE ALTA PRESSAO CITOCROMO P-450 ISOENZIMAS MICROSSOMOS HEPATICOS MICROSSOMOS HEPATICOS PROTEINAS RECOMBINANTES TALIDOMIDA Location: BR191.1; 08439/s

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Id: 11448 Author: Bansal, Rakesh; Garg, Bhagat R; Adithan, C; Vasireddit, Srinivas S; Kumar, Vijay; Chandra, Dinesh Title: Cortisol status in different types of leprosy ..- Source: s.l; s.n; 1995. 3 p. tab. Descriptors: DISTRIBUIÇAO DE QUI-QUADRADO CROMATOGRAFIA LIQUIDA DE ALTA PRESSAO CORTICOTROPINA HIDROCORTISONA HANSENIASE Location: BR191.1; 08331/s

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Id: 10284 Author: Rojas-Espinosa, O; Luna-Herrera, J; Arce-Paredes, P. Title: Recognition of phenolic glycolipid-I (Mycobacterium leprae) and sulfolipid-I (M. tuberculosis) by serum from Mexican patients with leprosy or tuberculosis ..- Source: s.l; s.n; 1999. 7 p. ilus, tab, graf. Descriptors: HANSENIASE MYCOBACTERIUM LEPRAE ANTIGENOS DE BACTÉRIAS CROMATOGRAFIA EM CAMADA DELGADA ELISA GLICOLIPIDIOS TUBERCULOSE Location: BR191.1. 7423/s

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Id: 10200 Author: O'Connor, Robert; O'Sullivan, J. F; O'Kennedy, Richard Title: The pharmacology, metabolism, and chemistry of clofazimine ..- Source: s.l; s.n; 1995. 24 p. ilus, tab. Descriptors: HANSENIASE MICOBACTERIOSE ABSORÇAO DISPONIBILIDADE BIOLOGICA CROMATOGRAFIA LIQUIDA DE ALTA PRESSAO CLOFAZIMINA CLOFAZIMINA CLOFAZIMINA CLOFAZIMINA SISTEMA IMUNE RELAÇAO ESTRUTURA-ATIVIDADE Location: BR191.1; 06974/s

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Id: 9945 Author: Moncrieff, Joan Title: Determination of dapsone in serum and saliva using reversed-phase high-perfomance liquid chromatography with ultraviolet or electrochemical detection ..- Source: s.l; s.n; 1994. 8 p. ilus, graf. Descriptors: HANSENIASE HANSENIASE CROMATOGRAFIA LIQUIDA DE ALTA PRESSAO CROMATOGRAFIA LIQUIDA DE ALTA PRESSAO DAPSONA DAPSONA DAPSONA ELETROQUIMICA MALARIA FALCIPARUM CONTROLE DE QUALIDADE SALIVA ESPECTROFOTOMETRIA ULTRAVIOLETA Location: BR191.1; 06846/s

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Id: 9822 Author: Kaushik, N. K; Sharma, Parul; Shah, Ashok; Venkitasubramanian, T. A Title: Serodiagnostic efficiency of phospholipid associated protein of Mycobacterium tuberculosis H37Rv ..- Source: s.l; s.n; 1993. 11 p. ilus, tab, graf. Descriptors: HANSENIASE LEPROMATOSA MYCOBACTERIUM TUBERCULOSIS ANTICORPOS ANTIBACTÉRIAS PROTEINAS DE BACTÉRIAS CROMATOGRAFIA EM CAMADA DELGADA ELISA REAÇOES FALSO-POSITIVAS IGG FOSFOLIPIDIOS VALOR PREDITIVO DOS TESTES RINITE SENSIBILIDADE E ESPECIFICIDADE TUBERCULOSE PULMONAR Location: BR191.1; 06726/s

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Id: 9694 Author: Gailly, Ch; David, Fr; Sandra, P; Laneelle, M. A; Cocito, C Title: Lipid composition of leprosy-derived corynebacteria, a distinct group of corynebacteria, and of a reference corynebacterium ..- Source: s.l; s.n; 1993. 18 p. ilus, tab, graf. Descriptors: PAREDE CELULAR CROMATOGRAFIA EM CAMADA DELGADA CORYNEBACTERIUM CORYNEBACTERIUM CORYNEBACTERIUM MEIOS DE CULTURA ACIDOS GRAXOS FRACIONAMENTO HANSENIASE LIPIDIOS LIPIDIOS FRAGMENTOMETRIA DE MASSA ACIDOS MICOLICOS ACIDOS ESTEARICOS Limits: ESTUDO COMPARATIVO Location: BR191.1; 06656/s

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Id: 9588 Author: Malfara, Wilson Roberto Title: Efeito de antagonistas de receptores H2 na metemoglobinemia induzida pela dapsona em ratos ?- Source: Ribeirao Preto; s.n; 2000. 114 p. ilus, tab, graf. Thesis: Present for Universidade de Sao Paulo. Faculdade de Ciencias Farmaceuticas de Ribeirao Preto presented for the degree Mestre. Abstract: Dapsona, farmaco bacteriostatico utilizado no tratamento da hanseniase, vem sendo associado a intercorrencias clinicas, principalmente devido a sua hemotoxicidade. A N-hidroxilacao, uma das principais vias de biotransformacao da dapsona vem sendo associada constantemente a quadros de metemoglobinemia decorrentes do uso da dapsona. Com objetivo de se verificar a inibicao reversivel desta via de bioativacao toxicologica, sem alterar os caminhos de detoxificacao do farmaco, a aceltilacao citosolica, a cimetidina, ranitidina e famotidina foram administradas concomitantemente a dapsona em ratos machos Wistar, com peso variando entre 200 e 250g divididos em 30 grupos (n=6), em estudo de doses unicas e multiplas. Apos as administracoes, os ratos foram submetidos a coleta de sangue(AU). Descriptors: HANSENIASE DAPSONA ANEMIA HEMOLITICA CIMETIDINA CROMATOGRAFIA LIQUIDA ANALISE ESTATISTICA TOXICOLOGIA METEMOGLOBINEMIA Location: BR191.1; WC335.102, M294e

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Id: 9490 Author: Fournie, Jean-Jacques; Mullins, Raymond; Basten, Antony Title: Isolation and structural characteristics of a monoclonal antibody-defined cross-reactive phospholipid antigen from Mycobacterium tuberculosis and Mycobacterium leprae ..- Source: s.l; s.n; 1991. 9 p. ilus, tab, graf. Descriptors: ANTICORPOS MONOCLONAIS ANTIGENOS DE BACTÉRIAS ANTIGENOS DE BACTÉRIAS CROMATOGRAFIA LIQUIDA DE ALTA PRESSAO CROMATOGRAFIA EM CAMADA DELGADA REAÇOES CRUZADAS ELETROFORESE EM GEL DE POLIACRILAMIDA ELISA EPITOPOS PESO MOLECULAR MYCOBACTERIUM LEPRAE MYCOBACTERIUM TUBERCULOSIS FOSFOLIPIDIOS ESPECTROMETRIA DE MASSA Location: BR191.1; 06346/s

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Id: 9363 Author: Jellum, E; Harboe, M; Bjune, G; Wold, S Title: Interpreting complicated chromatographic patterns ..- Source: s.l; s.n; 1991. 7 p. ilus, tab, graf. Descriptors: ISOMERASES DE AMINOACIDO AMINOACIDOS ACIDOS CARBOXILICOS CROMATOGRAFIA POR TROCA IONICA INTERPRETAÇAO ESTATISTICA DE DADOS ANALISE DOS MINIMOS QUADRADOS HANSENIASE Location: BR191.1; 06444/s

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Id: 9179 Author: Ferreira, Claudete Serrano Astolfi; Hamid, Doura Abdul; Train, Daysi Regina; Venancio, Emerson Jose; Itano, Eiko Nakagawa Title: Correlation between Rubino's reaction and soluble sheep erythrocyte receptors in Hansen's patients ..- Source: Londrina; s.n; 1994. 4 p. tab, graf. Descriptors: HEMATOCRITO HANSENIASE SORO ANTILINFOCITARIO ERITROCITOS LINFOCITOS T CROMATOGRAFIA IMUNODIFUSAO Location: BR191.1; 06147/s

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Id: 9129 Author: Itano, Eiko N; Somens, Carlos C; Kaminami, Mari S; Ferreira, Claudete S. A; Mazzarim, Aparecida M; Vieira, Aline A Title: Caracterizacao parcial de receptores soluveis E presentes em soros de pacientes com hanseniase Partial characterization of E-soluble receptor (Rs) presente in Hansen's disease (HD) patients sera- Source: s.l; s.n; 1995. 6 p. ilus, graf. Descriptors: HANSENIASE ERITROCITOS ANTIGENOS CD2 SORO ANTILINFOCITARIO IMUNOSSUPRESSAO ELISA CROMATOGRAFIA Location: BR191.1; 06085/s

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Id: 3855 Author: Minnikin, D. E; Dobson, G; Draper, P Title: The free lipids of Mycobacterium leprae harvested from experimentally infected nine-banded armadillos ..- Source: s.l; s.n; 1985. 4 p. ilus. Descriptors: HANSENIASE MYCOBACTERIUM LEPRAE MYCOBACTERIUM LEPRAE CROMATOGRAFIA EM CAMADA DELGADA LIPIDIOS LIPIDIOS TATUS Location: BR191.1; 02695/s

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Id: 3843 Author: Etemadi, A. H; Convit, J Title: Mycolic acids from "noncultivable" mycobacteria ..- Source: s.l; s.n; 1975. 3 p. graf. Descriptors: HANSENIASE HANSENIASE MYCOBACTERIUM LEPRAE MYCOBACTERIUM ACETONA ALCOOL ETILICO ÉTERES ACIDOS MICOLICOS MANIFESTAÇOES CUTANEAS ESPECTROMETRIA DE MASSA CROMATOGRAFIA EM CAMADA DELGADA Location: BR191.1; 02683/s

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Id: 3818 Author: Draper, P; Payne, Sheila N; Dobson, G; Minnikin, D. E Title: Isolation of a characteristic phthiocerol dimycocerosate from Mycobacterium leprae ..- Source: s.l; s.n; 1983. 5 p. ilus. Descriptors: HANSENIASE MYCOBACTERIUM LEPRAE MYCOBACTERIUM TUBERCULOSIS LIPIDIOS FIGADO TATUS IONIZAÇAO DE CHAMA CROMATOGRAFIA EM CAMADA DELGADA Location: BR191.1; 02658/s

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Id: 3808 Author: Young, Douglas B Title: Identification of Mycobacterium leprae: use of wall-bound mycolic acids ..- Source: s.l; s.n; 1980. 5 p. ilus. Descriptors: MYCOBACTERIUM LEPRAE PAREDE CELULAR CROMATOGRAFIA EM CAMADA DELGADA Location: BR191.1; 02648/s

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Id: 472 Author: Burchfield, H. P; Wheeler, R. J; Storrs, E. E. Title: Gas chromatographic analysis of DDS, MADDS and DADDS. Source: In: Annual Leprosy Research Conference, 4.Annual Leprosy Research Conference, 4/Abstracts of papers. San Francisco, U.S. Public Health Service Hospital, 1969. p.462. Conference: Present in: Annual Leprosy Research Conference, 4, San Francisco, 26-28 May 1969. Descriptors: SULFONAS CROMATOGRAFIA TERAPEUTICA Location: BR191.1; WC335.3, A78a

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