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Id: | 13435
| Author: | Wing Ling, Ng; Scollard, David M; Hua, Andrew
| Title: | Glomerulonephritis in leprosy
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| Source: | s.l; s.n; sep. 1981. 9 p. ilus, tab.
| Abstract: | A renal biopsy from a patient with lepromatous leprosy but no history of erythrema nodosum leprosum (ENL) showed histologic, immunofluorescent, and ultrastructural features typical of immune-complex glomerulonephritis. A literature review found reports of 187 renal biopsies from leprosy patients, with glomerulonephritis in 31% of the cases, and a variety of other renal lesions. This accumulated evidence demonstrates that, contrary to widely held opinion, there is no association between glomerulonephritis and a history of ENL. Furthermore, it suggests that glomerulonephritis in leprosy patients has a similar incidence in lepromatous and non-lepromatous cases. These observations have an important bearing on concepts regarding the pathogenesis of immune complex glomerulonephritis in leprosy and the humoral immune mechanisms in patients with leprosy.(AU).
| Descriptors: | COMPLEXO ANTIGENO-ANTICORPO BIOPSIA ERITEMA NODOSO DOENCAS DO COMPLEXO IMUNE/imunol GLOMERULONEFRITE/compl GLOMERULONEFRITE/imunol HANSENIASE/compl RIM/patol
| Limits: | RELATO DE CASO HUMANO MASCULINO MEIA-IDADE
| Electronic Medium: | http://www.ilsl.br
| Location: | BR191.1; 01782/s |
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