Database : HANSEN
Search on : GLOMERULONEFRITE/IMUNOL [Subject descriptor]
References found : 4 [refine]
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Id:13435
Author:Wing Ling, Ng; Scollard, David M; Hua, Andrew
Title:Glomerulonephritis in leprosy ..-
Source:s.l; s.n; sep. 1981. 9 p. ilus, tab.
Abstract:A renal biopsy from a patient with lepromatous leprosy but no history of erythrema nodosum leprosum (ENL) showed histologic, immunofluorescent, and ultrastructural features typical of immune-complex glomerulonephritis. A literature review found reports of 187 renal biopsies from leprosy patients, with glomerulonephritis in 31% of the cases, and a variety of other renal lesions. This accumulated evidence demonstrates that, contrary to widely held opinion, there is no association between glomerulonephritis and a history of ENL. Furthermore, it suggests that glomerulonephritis in leprosy patients has a similar incidence in lepromatous and non-lepromatous cases. These observations have an important bearing on concepts regarding the pathogenesis of immune complex glomerulonephritis in leprosy and the humoral immune mechanisms in patients with leprosy.(AU).
Descriptors:COMPLEXO ANTIGENO-ANTICORPO
BIOPSIA
ERITEMA NODOSO
DOENCAS DO COMPLEXO IMUNE/imunol
GLOMERULONEFRITE/compl
GLOMERULONEFRITE/imunol
HANSENIASE/compl
RIM/patol
Limits:RELATO DE CASO
HUMANO
MASCULINO
MEIA-IDADE
Electronic Medium:http://www.ilsl.br
Location:BR191.1; 01782/s


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Id:13367
Author:Date, Anand; Johny, K. V
Title:Glomerular subepithelial deposits in lepromatous leprosy ..-
Source:s.l; s.n; sep. 1975. 4 p. ilus, tab.
Abstract:The presence of subepithelial humps seen in the glomeruli on electron microscopy in a case of lepromatous leprosy with erythema nodosum leprosum is described. Negative cultures and normal antibody titers for streptococci suggest a nonstreptococcal etiology for this finding. Futher studies in this immune complex nephritis are required, to establish its relationship to lepromatous leprosy.(AU).
Descriptors:MEMBRANA BASAL/patol
ERITEMA NODOSO/patol
GLOMERULONEFRITE/imunol
GLOMERULONEFRITE/patol
DOENCAS DO COMPLEXO IMUNE/patol
HANSENIASE/imunol
HANSENIASE/patol
MYCOBACTERIUM LEPRAE/isol
Limits:RELATO DE CASO
HUMANO
MASCULINO
ADULTO
SUPPORT, U.S. GOV'T, NON-P.H.S.
Electronic Medium:http://www.ilsl.br
Location:BR191.1; 01796/s


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Id:13363
Author:Ng, Wing Ling; Scollard, David M; Hua, Andrew
Title:Glomerulonephritis in leprosy ..-
Source:s.l; s.n; sep. 1981. 9 p. ilus, tab.
Abstract:A renal biopsy from a patient with lepromatous leprosy but no history of erythrema nodosum leprosum (ENL) showed histologic, immunofluorescent, and ultrastructural features typical of immune-complex glomerulonephritis. A literature review found reports of 187 renal biopsies from leprosy patients, with glomerulonephritis in 31% of the cases, and a variety of other renal lesions. This accumulated evidence demonstrates that, contrary to widely held opinion, there is no association between glomerulonephritis and a history of ENL. Furthermore, it suggests that glomerulonephritis in leprosy patients has a similar incidence in lepromatous and non-lepromatous cases. These observations have an important bearing on concepts regarding the pathogenesis of immune complex glomerulonephritis in leprosy and the humoral immune mechanisms in patients with leprosy.(AU).
Descriptors:COMPLEXO ANTIGENO-ANTICORPO
BIOPSIA
ERITEMA NODOSO
DOENCAS DO COMPLEXO IMUNE/imunol
RIM/patol
HANSENIASE/compl
GLOMERULONEFRITE/compl
GLOMERULONEFRITE/imunol
Limits:RELATO DE CASO
HUMANO
MASCULINO
MEIA-IDADE
Electronic Medium:http://www.ilsl.br
Location:BR191.1; 01938/s


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Id:13307
Author:Date, Anand; Thomas, Alexander; Mathai, R; Johny, K. V
Title:Glomerular pathology in leprosy. An electron microscopic study ..-
Source:s.l; s.n; mar. 1977. 7 p. ilus, tab.
Abstract:Electron microscopic examination of renal biopsies from 19 patients with leprosy who had edema, proteinuria, or hematuria showed a proliferative glomerulonephritis in 12, amyloidosis in 2, and no lesion in 5. The proliferative glomerulonephritis was of different patterns: diffuse with or without exudation, focal, or mesangial. Subendothelial and/or subepithelial deposits were seen in five biopsies. Of the patients with glomerulonephritis, 3 had a reduced total serum complement level, 5 had erythema nodosum leprosum, 5 had evidence of recent streptococcal infection, and 2 had microfilariae in the peripheral blood. The significance of these findings is discussed.(AU).
Descriptors:GLOMERULOS RENAIS/irrig
GLOMERULOS RENAIS/patol
HANSENIASE/compl
HANSENIASE/imunol
HANSENIASE/patol
BIOPSIA
CAPILARES/patol
GLOMERULONEFRITE/compl
GLOMERULONEFRITE/imunol
GLOMERULONEFRITE/patol
ERITEMA NODOSO/compl
 ERITEMA NODOSO/patol
Limits:HUMANO
MASCULINO
ADULTO
MEIA-IDADE
Location:BR191.1; 00841/s



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