Database : HANSEN Search on : ESTRADIOL/SANGUE [Subject descriptor] References found : 3 [refine] Displaying: 1 .. 3   in format [Detailed]

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Id: 13492 Author: Kannan, V; Vijaya, G Title: Endocrine testicular functions in leprosy ..- Source: s.l; s.n; mar. 1984. 5 p. tab. Abstract: Pituitary testicular functions were evaluated in leprosy. Forty-three men with leprosy were studied by basal estimations of plasma LH, FSH, Prolactin, Testosterone, 17-beta estradiol, metoclopramide stimulated prolactin responses and hCG stimulated testosterone responses. Fifteen young healthy men with proven fertility were studied as control subjects. The hormone estimations were related to the histologic changes observed in the testicular biopsies of leprous hypogonadism. In lepromatous leprosy (n:18) the basal plasma gonadotropin levels were significantly increased (FSH 29.5 +/- 2.3 mlU/ml; LH 21.5 +/- 1.9 mlU/ml, mean +/- SE). The plasma gonadotropins were in the normal range in tuberculoid leprosy. In borderline leprosy, the basal mean plasma FSH was normal, whereas LH levels were significantly increased (22.5 +/- 1.2 mlU/ml). The basal plasma testosterone levels were significantly decreased in lepromatous leprosy (1.6 +/- 0.12 ng/ml), tuberculoid leprosy (4.2 +/- 1.7 ng/ml) and borderline leprosy (1.8 +/- 0.18 ng/ml). The basal plasma 17-beta estradiol levels were significantly elevated in all the three types of leprosy. The basal plasma prolactin levels in plasma were significantly increased in lepromatous and tuberculoid leprosy. During hCG stimulation tests, the peak plasma testosterone responses were significantly reduced in both lepromatous leprosy and tuberculoid leprosy subjects. The blunted testosterone responses during hCG stimulation tests in leprosy correlated with the high basal 17-beta estradiol levels (r = 0.58; P less than 0.05). These results strongly suggest that hypogonadism in leprosy results from primary testicular failure. The significant elevation of plasma 17-beta estradiol levels in lepromatous, tuberculoid and borderline leprosy could play a role in hypogonadism of leprosy.(AU). Descriptors: METOCLOPRAMIDA/uso diag HIPOGONADISMO/sangue HIPOGONADISMO/etiol HANSENIASE/sangue HANSENIASE/compl HANSENIASE/etiol HORMÔNIO FOLICULO ESTIMULANTE/sangue ESTRADIOL/sangue HORMÔNIOS/sangue GONADOTROPINAS/uso diag Limits: HUMANO MASCULINO ADULTO MEIA-IDADE Electronic Medium: http://www.ilsl.br Location: BR191.1; 01616/s

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Id: 13221 Author: Morley, John E; Distiller, Larry A; Sagel, Julius; Kok, S. H; Kay, Graham; Carr, Peter; Katz, Maurice Title: Hormonal changes associated with testicular atrophy and gynaecomastia in patients with leprosy ..- Source: s.l; s.n; apr. 1977. 5 p. graf. Abstract: Basal LH, FSH, 17 beta-oestradiol and testosterone and the gonadotrophin responses to luteinizing hormone releasing hormone (LHRH) were studied in male patients with leprosy (twenty-four with lepromatous and six with tuberculoid leprosy). The mean basal LH and FSH was significantly elevated in the lepromatous group and was associated with an excessive response of both gonadotrophins following LHRH administration. The mean basal testosterone and 17 beta-oestradiol values in the lepromatous group were significantly lower than those of the tuberculoid and control groups. The abnormal gonadotrophin and sex steroid values in the lepromatous group are in keeping with the testicular atrophy and gynaecomastia accompanying this form of leprosy. However, the lack of a significant correlation between basal FSH and testicular atrophy should be noted. In addition, no correlation between any of these hormonal values and gynaecomastia could be demonstrated. The patients with tuberculoid leprosy had essentially normal hormonal profiles (except for two who had raised 17 beta-oestradiol values). This is compatible with the lack of gonadal involvement in these patients.(AU). Descriptors: ESTRADIOL/sangue HORMÔNIO FOLICULO ESTIMULANTE/sangue HANSENIASE/compl GINECOMASTIA/etiol LH/sangue DOENCAS TESTICULARES/etiol TESTICULO/patol TESTOSTERONA/sangue GONADORELINA/farmacol Limits: ESTUDO COMPARATIVO HUMANO MASCULINO ADULTO ADOLESCENTE Electronic Medium: http://www.ilsl.br Location: BR191.1; 01584/s

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Id: 10109 Author: Ishikawa, Satoshi; Tanaka, Hiroyuki; Mizushima, Mutsue; Hashizume, Hiroyuki; Ishida, Yutaka; Inoue, Hajime Title: Osteoporosis due to testicular atrophy in male leprosy patients ..- Source: s.l; s.n; 1997. 5 p. ilus, tab. Descriptors: ATROFIA DENSIDADE OSSEA ESTRADIOL LH HANSENIASE OSTEOPOROSE TESTICULO TESTOSTERONA Location: BR191.1; 07050/s

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