Database : HANSEN Search on : ENVELHECIMENTO [Subject descriptor] References found : 5 [refine] Displaying: 1 .. 5   in format [Detailed]

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Id: 13431 Author: Melsom, R; Duncan, M. E; Harboe, M; Bjune, G Title: Antibodies against Mycobacterium leprae antigen 7 from birth to 18 months of age: an indicator of intra-uterine infection in leprosy ..- Source: s.l; s.n; oct. 1980. 7 p. tab, graf. Abstract: All babies of three non-leprosy mothers and ten tuberculoid leprosy mothers and four of five babies of mothers with inactive lepromatous leprosy showed a decline in serum concentration of antibodies against M. leprae antigen 7 during the first 4 months of life, as expected from catabolism of maternal IgG. By contrast, ten of twenty babies of mothers with active lepromatous leprosy showed a decline in concentration of anti-M. leprae 7 antibodies considerably less than expected. This indicates that these babies have been stimulated by M. leprae antigen 7, either as free antigen or by viable M. leprae before birth, and thus that leprosy may occur as a congenital infection. Studies of anti-M. leprae antibodies in repeated serum samples obtained during the first 18 months of life indicated that children of mothers with bacilliferous leprosy are frequently exposed to M. leprae to a sufficient extent to stimulate the immune system of the baby to production of anti-M. leprae antibodies during this period. The consequences of this exposure to M. leprae should be ascertained by careful clinical studies.(AU). Descriptors: HANSENIASE/imunol TROCA MATERNO-FETAL MYCOBACTERIUM LEPRAE/imunol IMUNOGLOBULINA G/metab ENVELHECIMENTO SANGUE FETAL/imunol ANTIGENOS DE BACTERIAS/imunol ANTICORPOS ANTIBACTERIAS/anal Limits: HUMANO FEMININO GRAVIDEZ RECÉM-NASCIDO LACTENTE SUPPORT, NON-U.S. GOV'T Electronic Medium: http://www.ilsl.br Location: BR191.1; 00461/s

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Id: 13377 Author: Blumberg, Baruch S; Melartin, Liisa; Lechat, Michel; Guinto, Ricardo S Title: Association between lepromatous leprosy and Australia antigen ..- Source: s.l; s.n; July 22, 1967. 4 p. tab. Abstract: Australia antigen is more common in patients with lepromatous leprosy than in patients with tuberculoid leprosy or in non-leprosy controls. In the combined populations, the frequency is, in general, higher in males than females, and in younger people than in older people. Australia antigen has now been found to be associated with lepromatous leprosy, leukaemia, and hepatitis, and to cluster in families. It is sugegsted that indivuduals with Australia antigen have an inadequate immune response and are especially susceptible to various illness, including lepromatous leprosy.(AU). Descriptors: HANSENIASE/sangue HANSENIASE/diag HANSENIASE/genet HANSENIASE/imunol ANALISE FATORIAL HEPATITE/imunol ENVELHECIMENTO ANTIGENOS - SEXO  COMPUTADORES Limits: HUMANO MASCULINO FEMININO LACTENTE PRÉ-ESCOLAR CRIANÇA ADULTO MEIA-IDADE IDOSO ADOLESCENTE Electronic Medium: http://www.ilsl.br Location: BR191.1; 01495/s

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Id: 13277 Author: Rasbridge, Marian R; Scott, G. L Title: The haemolytic action of dapsone: the effect on red-cell glycolysis ..- Source: s.l; s.n; feb. 1973. 13 p. tab, graf. Abstract: Some aspects of red-cell matabolism were studied in blood samples taken from patients on long-term dapsone therapy. Glucose consumption by the Embden-Meyerhof pathway (EMP) was not abnormal and adenosine-triphosphate (ATP) levels lay within the normal range and were well maintained during incubation. Hexose monophosphate patchway (HMP) activity was increased above that which would be expected from the age of the red-cell population. Red-cell reduced glutathione (GSH) levels tended to be lower than normal, proportional to the dose od dapsone and GSH levels were unstable on incubation. Red-cell fractionation studies showed that the older cell fraction had lower GSH levels and more Heinz bodies but proportionally greater HMP activity than the younger cell fraction. It is suggested that the low GSH levels are probably due to the binding of GSH to sulphydryl groups in haemoglobin and possibly the red-cell membrane. The increased HMP activity in the older cells many, in part, be a compensatory mechanism.(AU). Descriptors: ADENOSINA TRIFOSFATO/sangue DAPSONA/ef adv DAPSONA/farmacol DERMATITE HERPETIFORME/quimioter ENVELHECIMENTO ERITROCITICO ERITROCITOS/enzimol ERITROCITOS/metab GLUCOSEFOSFATO DESIDROGENASE/sangue GLUTATIONA/sangue CORPOS DE HEINZ Electronic Medium: http://www.ilsl.br Location: BR191.1; 01856/s

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Id: 10013 Author: Chui, De-Hua; Tabira, Takeshi; Izumi, Shinzo; Koya, Goyo; Ogata, Jun Title: Decreased beta-amyloid and increased abnormal Tau deposition in the brain of aged patients with leprosy ..- Source: s.l; s.n; 1994. 5 p. ilus, tab, graf. Descriptors: IDOSO IDOSO DE 80 ANOS OU MAIS ENVELHECIMENTO DOENÇA DE ALZHEIMER DOENÇA DE ALZHEIMER PROTEINA BETA AMILOIDE CÉREBRO CÉREBRO CONTAGEM DE CÉLULAS HIPOCAMPO HIPOCAMPO IMUNOHISTOQUIMICA HANSENIASE HANSENIASE NEURONIOS VALORES DE REFERENCIA LOBO TEMPORAL LOBO TEMPORAL PROTEINAS TAU Location: BR191.1; 06909/s

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Id: 9896 Author: Gatti, Giorgio; Loy, Anna; Casazza, Roseta; Miletich, Franca; Cruciani, Mario; Bassetti, Dante Title: Pharmacokinetics of dapsone in human immunodeficiency virus-infected children ..- Source: s.l; s.n; 1995. 6 p. tab, graf. Descriptors: DAPSONA DAPSONA DAPSONA DAPSONA ENVELHECIMENTO ANTIINFECCIOSOS INFECÇOES POR HIV MEIA-VIDA PNEUMONIA POR PNEUMOCYSTIS CARINII Location: BR191.1; 06781/s

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