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HANSEN
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DISTROFINA [Subject descriptor]
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Id:
17690
Author:
Rambukkana, Anura
Title:
Mycobacterium leprae-induced demyelination: a model for early nerve degeneration ..-
Source:
s.l; s.n; 2004. 8 p. ilus, tab.
Abstract:
The molecular events that occur at the early phase of many demyelinating neurodegenerative diseases are unknown. A recent demonstration of rapid demyelination and axonal injury induced by Mycobacterium leprae provides a model for elucidating the molecular events of early nerve degeneration which might be common to neurodegenerative diseases of both infectious origin and unknown etiology. The identification of the M. leprae-targeted Schwann cell receptor, dystroglycan, and its associated molecules in myelination, demyelination and axonal functions suggests a role for these molecules in early nerve degeneration. (AU).
Descriptors:
Axônios/IM/PA/UL
Doenças Auto-Imunes Desmielinizantes do Sistema Nervoso Central/ET/*IM/MI/PP
Distroglicanas/*IM
Complexo de Proteínas Associadas Distrofina/IM
Hanseníase/CO/*IM
Mycobacterium leprae/*IM
Bainha de Mielina/*IM
Células de Schwann/*IM/MI/PA
Limits:
HUMANO
ANIMAL
CAMUNDONGOS
SUPPORT, U.S. GOV'T, NON-P.H.S.
SUPPORT, U.S. GOV'T, P.H.S.
Location:
BR191.1; 09364/S
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Id:
13720
Author:
Brophy, Peter J
Title:
Subversion of schwann cells and the leper's bell ..-
Source:
s.l; s.n; May 3, 2002. 2 p. ilus.
Descriptors:
AXONIOS/PH
MORTE CELULAR
DIFERENCIACAO CELULAR
MEMBRANA CELULAR/ME
COCULTURA
PROTEINAS CITOESQUELETO/ME
DOENCAS DESMIELINIZANTES/*MI
DISTROFINA/ME
GLICOLIPIDEOS/ME
LAMININA/ME
HANSENIASE/*MI/PA/*PP
GLICOPROTEINAS DE MEMBRANA/ME
PROTEINAS DE MEMBRANA/ME
MYCOBACTERIUM LEPRAE/GD/ME/*PY
BAINHA DE MIELINA/*PH
CELULAS DE SCHWANN/CY/*MI/*PH
Limits:
ANIMAL
HUMANO
CAMUNDONGOS
Location:
BR191.1; 09065/s
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Id:
12312
Author:
Brophy, Peter J
Title:
Subversion of Schwann cells and the leper's bell ..-
Source:
s.l; s.n; May 2002. 2 p. ilus.
Descriptors:
AXONIOS
MORTE CELULAR
DIFERENCIAÇAO CELULAR
MEMBRANA CELULAR
COCULTURA
PROTEINAS CITOESQUELETO
DOENÇAS DESMIELINIZANTES
DISTROFINA
GLICOLIPIDIOS
LAMININA
HANSENIASE
HANSENIASE
HANSENIASE
GLICOPROTEINAS DE MEMBRANAS
PROTEINAS DA MEMBRANA
CAMUNDONGOS
MYCOBACTERIUM LEPRAE
MYCOBACTERIUM LEPRAE
MYCOBACTERIUM LEPRAE
BAINHA DE MIELINA
CÉLULAS DE SCHWANN
CÉLULAS DE SCHWANN
CÉLULAS DE SCHWANN
Limits:
ANIMAL
Location:
BR191.1; 08621/s
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Id:
11744
Author:
Brophy, Peter J
Title:
Subversion of Schwann cells and the leper's Bell ..-
Source:
s.l; s.n; 2002. 2 p. ilus.
Descriptors:
HANSENIASE
HANSENIASE
HANSENIASE
MYCOBACTERIUM LEPRAE
MYCOBACTERIUM LEPRAE
MYCOBACTERIUM LEPRAE
AXONIOS
DIFERENCIAÇAO CELULAR
MEMBRANA CELULAR
COCULTURA
PROTEINAS CITOESQUELETO
DOENÇAS DESMIELINIZANTES
DISTROFINA
GLICOLIPIDIOS
LAMININA
GLICOPROTEINAS DE MEMBRANAS
BAINHA DE MIELINA
CÉLULAS DE SCHWANN
CÉLULAS DE SCHWANN
CÉLULAS DE SCHWANN
Location:
BR191.1; 08527/s
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