Database : HANSEN Search on : COMPLEXO PRINCIPAL DE HISTOCOMPATIBILIDADE/IMUNOL [Subject descriptor] References found : 7 [refine] Displaying: 1 .. 7   in format [Detailed]

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Id: 13929 Author: Fitness, J; Tosh, K; Hill, A. V. S Title: Genetics of susceptibility to leprosy ..- Source: s.l; s.n; Dec. 2002. 13 p. tab. Abstract: The ancient disease of leprosy can cause severe disability and disfigurement and is still a major health concern in many parts of the world. Only a subset of those individuals exposed to the pathogen will go on to develop clinical disease and there is a broad clinical spectrum amongst leprosy sufferers. The outcome of infection is in part due to host genes that influence control of the initial infection and the host's immune response to that infection. Identification of the host genes that influence host susceptibility/resistance will enable a greater understanding of disease pathogenesis. In turn, this should facilitate development of more effective therapeutics and vaccines. So far at least a dozen genes have been implicated in leprosy susceptibility and a genome-wide linkage study has lead to the identification of at least one positional candidate. These findings are reviewed here. (AU). Descriptors: PREDISPOSICAO GENETICA PARA DOENÇA/genet HANSENIASE/genet HANSENIASE/imunol LIGACAO (GENETICA)/genet LIGACAO (GENETICA)/imunol COMPLEXO PRINCIPAL DE HISTOCOMPATIBILIDADE/genet COMPLEXO PRINCIPAL DE HISTOCOMPATIBILIDADE/imunol Limits: HUMANO ANIMAL Electronic Medium: http://www.ilsl.br Location: BR191.1; 09106/s

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Id: 11720 Author: Aleman, M; Barrera, S. de la; Fink, S; Finiasz, M; Arinna, M. H; Pizzariello, G; Sasiain, M. del C Title: Interleukin-12 amplifies the M. leprae hsp65-cytotoxic responses in the presence of tumor necrosis factor-alpha and interferon-gamma generating CD56+ effector cells: interleukin-4 downregulates this effect ..- Source: s.l; s.n; 2000. 9 p. tab, graf. Descriptors: HANSENIASE MYCOBACTERIUM LEPRAE ANTIGENOS CD56 CHAPERONINAS CITOTOXICIDADE IMUNOLOGICA SINERGISMO DE DROGAS SOROS IMUNES INTERFERON TIPO II INTERLEUCINA-10 INTERLEUCINA-12 INTERLEUCINA-12 INTERLEUCINA-12 INTERLEUCINA-4 INTERFASE LEUCOCITOS MONONUCLEARES LEUCOCITOS MONONUCLEARES TRANSFORMAÇAO LINFOCITICA COMPLEXO PRINCIPAL DE HISTOCOMPATIBILIDADE LIGAÇAO PROTÉICA LINFOCITOS T CITOTOXICOS LINFOCITOS T CITOTOXICOS FATOR DE NECROSE DE TUMOR FATOR DE NECROSE DE TUMOR FATOR DE NECROSE DE TUMOR Location: BR191.1; 07463/s

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Id: 11025 Author: Ulrichs, T; Porcelli, S. A Title: CD1 proteins: targets of T cell recognition in innate and adaptive immunity ..- Source: s.l; s.n; 2000. 17 p. ilus, tab. Descriptors: FORMAÇAO DE ANTICORPOS APRESENTAÇAO DO ANTIGENO ANTIGENOS DE BACTÉRIAS ANTIGENOS DE BACTÉRIAS ANTIGENOS CD1 ANTIGENOS CD1 ANTIGENOS CD1 ANTIGENOS CD1 EVOLUÇAO MOLECULAR GLICOLIPIDIOS GLICOLIPIDIOS IMUNIDADE NATURAL CÉLULAS KILLER NATURAIS HANSENIASE LIPIDIOS LIPIDIOS COMPLEXO PRINCIPAL DE HISTOCOMPATIBILIDADE MAMIFEROS MAMIFEROS CAMUNDONGOS MODELOS MOLECULARES MYCOBACTERIUM MYCOBACTERIUM CONFORMAÇAO PROTÉICA ESTRUTURA TERCIARIA DE PROTEINA RATOS RECEPTORES PARA ANTIGENOS DE CÉLULAS T GAMA-DELTA ESPECIFICIDADE DE ESPÉCIES SUB-POPULAÇOES DE LINFOCITOS T TUBERCULOSE Isoformas de Proteínas/CH/CL/GE/IM Limits: ANIMAL Location: BR191.1; 07486/s

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Id: 10364 Author: Baum, Harold; Staines, Norman Title: MHC-derived peptides and the CD4+ T-cell repertoire: implications for autoimmune disease ..- Source: s.l; s.n; 1997. 11 p. ilus. Descriptors: ALELOS SEQUENCIA DE AMINOACIDOS ARTRITE REUMATOIDE AUTO-ANTIGENOS DOENÇAS AUTO-IMUNES DOENÇAS AUTO-IMUNES DOENÇAS AUTO-IMUNES LINFOCITOS B LINFOCITOS T CD4-POSITIVOS DOENÇA DE CHAGAS DIABETES MELLITUS INSULINO-DEPENDENTE ANTIGENOS DE HISTOCOMPATIBILIDADE EPITOPOS IMUNODOMINANTES HANSENIASE CIRROSE HEPATICA BILIAR COMPLEXO PRINCIPAL DE HISTOCOMPATIBILIDADE MODELOS BIOLOGICOS MIMETISMO MOLECULAR - UVEITE Limits: ANIMAL Location: BR191.1; 07496/s

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Id: 10235 Author: Messias, I. J. T. de; Santamaria, J; Brenden, M; Reis, A; Mauff, G Title: Association of C4B deficiency (C4B*Q0) with erythema nodosum in leprosy ..- Source: s.l; s.n; 1993. 4 p. tab. Descriptors: COMPLEMENTO 4B COMPLEMENTO 4B PROPERDINA FATOR B ERITEMA NODOSO ERITEMA NODOSO FREQUENCIA DOS GENES HANSENIASE HANSENIASE COMPLEXO PRINCIPAL DE HISTOCOMPATIBILIDADE Location: BR191.1; 06936/s

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Id: 10178 Author: Rajalingam, R; Singal, D. P; Mehra, N. K Title: Transporter associated with antigen-processing (TAP) genes and susceptibility to tuberculoid leprosy and pulmonary tuberculosis ..- Source: s.l; s.n; 1997. 5 p. tab. Descriptors: TRANSPORTADORES ABC SUSCETIBILIDADE A DOENÇA HANSENIASE TUBERCULOIDE HANSENIASE TUBERCULOIDE DESEQUILIBRIO DE LIGAÇAO COMPLEXO PRINCIPAL DE HISTOCOMPATIBILIDADE TUBERCULOSE PULMONAR TUBERCULOSE PULMONAR Location: BR191.1; 07091/s

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Id: 9745 Author: Mutis, Tuna; Cornelisse, Yolanthe E; Datema, Gert; Van Den Elsen, Peter J; Ottenhoff, tom H. M; Vries, Rene R. P. de Title: Definition of a human suppressor T-cell epitope ..- Source: s.l; s.n; 1994. 5 p. tab, graf. Descriptors: SEQUENCIA DE AMINOACIDOS ANTIGENOS DE BACTÉRIAS LINFOCITOS T CD4-POSITIVOS CÉLULAS CLONAIS EPITOPOS EPITOPOS ANTIGENO HLA-DR2 HANSENIASE TRANSFORMAÇAO LINFOCITICA COMPLEXO PRINCIPAL DE HISTOCOMPATIBILIDADE DADOS DE SEQUENCIA MOLECULAR MYCOBACTERIUM LEPRAE REAÇAO EM CADEIA POR POLIMERASE RECEPTORES PARA ANTIGENOS DE CÉLULAS T ALFA-BETA RECEPTORES PARA ANTIGENOS DE CÉLULAS T ALFA-BETA PROTEINAS RECOMBINANTES PELE LINFOCITOS T SUPRESSORES-EFETORES Location: BR191.1; 06704/s

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