Database : HANSEN Search on : MACACA MULATTA [Subject descriptor] References found : 6 [refine] Displaying: 1 .. 6   in format [Detailed]

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Id: 19533 Author: Gormus, Bobby J; Baskin, Gary B; Xu, Keyu; Ratterree, Marion S; Martin, Louis N; Mack, Pamela A; Bohm Jr, Rudolf P; Meyers, Wayne M; Walsh, Gerald P. Title: Antileprosy protective vaccination of rhesus monkeys with BCG or BCG plus heat-killed mycobacterium leprae: immunologic observations. Source: Int. J. Lepr;68(1):27-39, Mar., 2000. graf. Abstract: Groups of rhesus monkeys were vaccinated and boosted with Mycobacterium bovis bacillus Calmette Guerin (BCG) or BCG plus low-dose (LD) or high-dose (HD) heat-killed M. leprae (HKML), or were unvaccinated. Prior to and following vaccination-boosting and subsequent M. leprae (ML) challenge, these and unvaccinated, unchallenged control monkeys were observed longitudinally for approximately 3 years. Vaccination with BCG plus HKML initially stimulated significant in vitro blood mononuclear cell blastogenic responses to lepromin, which returned to baseline post-boosting and post-live-ML-challenge, minimally reappearing significantly 2 years post-ML-challenge. Vaccination with BCG failed to stimulated positive blastogenic responses to lepromin before ML-challenge but small, marginally positive, intermittent responses were seen post-ML-challenge. Compared to the unvaccinated ML-challenged group, significant increases in the numbers of blood CD4+ and CD8+ T-cell subsets and an increased CD4+:CD8+ ratio were observed in both BCG plus HKML-vaccinated, ML-challenged groups, but not in the BCG-only-vaccinated, ML-challenged group. CD4+CD29+ and CD4+CD45RA+ subset numbers increased significantly over time in only the BCG plus LD HKML-vaccinated, ML-challenged group. Compared to unvaccinated, ML-challenged groups, vaccination with BCG or BCG plus HKML followed by ML-challenge produced lower IgM:IgG antiphenolic glycolipid-I (PGL-I) serum antibody ratios and protected rhesus monkeys from clinical leprosy, consistent with prior observations that low IgM:IgG anti-PGL-I responses correlated with resistance to and protection from leprosy. (AU)^ien. Descriptors: Mycobacterium leprae/imunol Macaca mulatta/genet Macaca mulatta/imunol Vacina BCG/imunol Vacina BCG/uso terap Limits: Animais Electronic Medium: http://hansen.bvs.ilsl.br/textoc/revistas/intjlepr/2000/pdf/v68n1/v68n1a05.pdf / en Location: BR191.1

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Id: 13269 Author: Hagstad, Harry V Title: Leprosy in sub-human primates: potential risk for transfer of M. leprae to humans ..- Source: s.l; s.n; dec. 1983. 5 p. tab. Abstract: Twenty six owned monkeys were examined in Andhra Pradesh, India during the period May-July, 1982. The prevalence rate among humans in daily contact with these monkeys was 98.6/1000. None of the monkeys examined had any evidence of current infection with M. leprae but six were in daily contact with individuals who had leprosy. All six of these monkeys were used for begging and had daily physical contact with large numbers of people, particularly children.(AU). Descriptors: ANIMAIS DOMESTICOS INDIA HANSENIASE/epidemiol HANSENIASE/transm HANSENIASE/vet MACACA MULATTA MACACA RADIATA DOENCAS DOS MACACOS/epidemiol DOENCAS DOS MACACOS/transm Limits: HUMANO ANIMAL MASCULINO FEMININO CRIANÇA SUPPORT, NON-U.S. GOV'T Electronic Medium: http://www.ilsl.br Location: BR191.1. 1641/s

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Id: 9630 Author: Parida, S. K; Grau, G. E Title: Role of TNF in immunopathology of leprosy ..- Source: s.l; s.n; 1993. 9 p. ilus. Descriptors: CITOCINAS HANSENIASE HANSENIASE HANSENIASE HANSENIASE LEPROMATOSA HANSENIASE LEPROMATOSA HANSENIASE LEPROMATOSA MACACA MULATTA MACROFAGOS CAMUNDONGOS CAMUNDONGOS DE CEPAS ENDOGAMICAS TUBERCULOMA TUBERCULOMA FATOR DE NECROSE TUMORAL/*PH Limits: ANIMAL Location: BR191.1; 06562/s

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Id: 9384 Author: Mistry, Yasmin; Young, Douglas B; Mukherjee, Rama Title: hsp70 synthesis in schwann cells in response to heat shock and infection with Mycobacterium leprae ..- Source: s.l; s.n; 1992. 6 p. ilus. Descriptors: CALOR PROTEINAS DO CHOQUE TÉRMICO HANSENIASE HANSENIASE MACACA MULATTA CAMUNDONGOS CAMUNDONGOS ENDOGAMICOS BALB C FAGOCITOSE CÉLULAS DE SCHWANN CELULAS CULTIVADAS Limits: ANIMAL Location: BR191.1; 06420/s

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Id: 9328 Author: Serme, Abdel K Title: L'infection par le virus de l'immunodeficience humaine et lepre ..- Source: s.l; s.n; 1992. 6 p. tab. Descriptors: AFRICA ASIA SUDESTE COMORBILIDADE INFECÇOES POR HIV INFECÇOES POR HIV INFECÇOES POR HIV SOROPREVALENCIA DE HIV HIV-1 INCIDENCIA INDIA HANSENIASE HANSENIASE HANSENIASE MACACA MULATTA Limits: ANIMAL Location: BR191.1; 06473/s

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Id: 9293 Author: Meyers, Wayne M; Gormus, Bobby J; Walsh, Gerald P; Baskin, Gary B; Hubbard, Gene B Title: Naturally acquired and experimental leprosy nonhuman primates ..- Source: s.l; s.n; 1991. 4 p. ilus. Conference: Present in: Special Symposium on Hansen's Disease: Advances in Clinical and Experimental Research, Honolulu, 14 december 1989. Descriptors: CERCOPITHECIDAE CERCOPITHECUS AETHIOPS MODELOS ANIMAIS DE DOENÇAS HYLOBATES HANSENIASE MACACA MULATTA DOENÇAS DOS MACACOS PONGIDAE Location: BR191.1; 06226/s; 06369/s

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