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HANSEN
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CALOR [Subject descriptor]
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Id:
13456
Author:
Shepard, Charles C; Walker, Laura L; Van Landingham, Rosalind
Title:
Heat stability of Mycobacterium leprae immunogenicity ..-
Source:
s.l; s.n; oct. 1978. 7 p. tab, graf.
Abstract:
The protection provided to mice by vaccines administered intradermally was measured after footpad challenge with Mycobacterium leprae. The protection offered by M. leprae suspensions was not decreased when the vaccines were killed by 60 degrees C heat or at the higher temperatures tested, which included 215 degrees C (autoclave). Even highly purified suspensions retained their immunogenicity. In contrast, the vaccine protection provided by intradermal M. bovis (strain BCG) was markedly reduced when heated to 60 degrees C. The enlargement of the lymph nodes regional to the intradermal vaccines was measured and found generally to parallel the vaccine protection provided by M. leprae and by BCG.(AU).
Descriptors:
MYCOBACTERIUM BOVIS
HANSENIASE/imunol
MYCOBACTERIUM LEPRAE/imunol
INJECOES SUBCUTÂNEAS
INJECOES INTRADERMICAS
VACINA BCG
IMUNIDADE CELULAR
VACINAS BACTERIANAS/admin
VACINAS BACTERIANAS/imunol
VACINAS BACTERIANAS/normas
-
CONGELAMENTO
CALOR
Limits:
ANIMAL
CAMUNDONGOS
SUPPORT, U.S. GOV'T, P.H.S.
Electronic Medium:
http://www.ilsl.br
Location:
BR191.1; 00293/s
2 / 8
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Id:
13443
Author:
Kashiwabara, Yoshiko; Nakagawa, Hiroko; Matsuki, Genji
Title:
Phospholipid deacylating activities in murine leprosy bacilli ..-
Source:
s.l; s.n; dec. 1980. 8 p. tab, graf.
Abstract:
1) The particulate fraction of cultivated murine leprosy bacilli (Mycobacterium lepraemurium, rough colonies of the Hawaiian-Ogawa strain) contained phospholipid deacylating activities with acidic pH optima. It hydrolyzed phosphatidylcholine and phosphatidylethanolamine at similar rates, and phosphatidylinositol oligomannosides more slowly. It also hydrolyzed 1-acyl- and 2-acyl-GPCs (sn-glycerol 3-phosphocholine) more rapidly than phosphatidylcholine. 2) Ca2+ did not stimulate either diacyl- or monoacyl-hydrolase activity. Triton X-100 and Emulgen 913 had little influence on the hydrolysis of phosphatidylcholine, but at rather high concentrations inhibited the hydrolyses of 1-acyl- and 2-acyl-GPCs. Iron ions strongly inhibited the hydrolysis of phosphatidylcholine, but caused little or no inhibition of the deacylations of 1-acyl- and 2-acyl-GPCs. 3) With 1-[stearoyl-14C]phosphatidylcholine and 2-[oleoyl-14C]phosphatidylcholine as substrates, both labeled fatty acid and lysophosphatidylcholine were produced. Labeled fatty acid appeared more rapidly from 2-[oleoyl-14C]phosphatidylcholine than labeled lysophosphatidylcholine, while labeled lysophosphatidylcholine was produced more than labeled fatty acid from 1-[stearoyl-14C]phosphatidylcholine in the early stage of incubation.(AU).
Descriptors:
FOSFOLIPIDIOS/metab
HIDROLISE
HIDROLASES/metab
CONCENTRACAO DE IONS DE HIDROGÊNIO
FERRO/farmacol
MYCOBACTERIUM LEPRAEMURIUM/metab
DETERGENTES/farmacol
FOSFATIDILCOLINAS/metab
CALOR
Limits:
ANIMAL
FEMININO
CAMUNDONGOS
Electronic Medium:
http://www.ilsl.br
Location:
BR191.1; 00689/s
3 / 8
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Id:
13321
Author:
Saha, Kunal; Mittal, Mmdan M; Ray, S. N
Title:
Consequences of smallpox vaccination in leprosy patients ..-
Source:
s.l; s.n; sep. 1973. 8 p. tab.
Abstract:
This study illustrates the consequences of smallpox revaccination in 45 lepromatous, 28 tuberculoid, and 47 normal individuals. Results obtained with leprosy were associated with a relative anergy against the vaccinia virus, the anergy being minimal in the tuberculoid leprosy but marked in the cases with lepromatous leprosy.(AU).
Descriptors:
HIPERSENSIBILIDADE TARDIA/imunol
IMUNIDADE CELULAR
IMUNOGLOBULINA A/anal
IMUNOGLOBULINA G/anal
IMUNOGLOBULINA M/anal
INJECOES INTRADERMICAS
HANSENIASE/imunol
VACINA ANTIVARIOLICA/admin
VACINACAO/ef adv
VIRUS DA VACÍNIA/imunol
-
FORMACAO DE ANTICORPOS
CALOR
HEMAGLUTINACAO
IMUNIZACAO SECUNDARIA
INIBICAO (PSICOLOGIA)
MERCAPTOETANOL
COMPLEMENTO/anal
IMUNODIFUSAO
Limits:
HUMANO
ADULTO
Electronic Medium:
http://www.ilsl.br
Location:
BR191.1; 01256/s
4 / 8
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Id:
13214
Author:
Srinivasan, H; Stumpe, B
Title:
Leprosy diagnosis: a device for testing the thermal sensibility of skin lesions in the field ..-
Source:
s.l; s.n; 1989. 7 p. ilus, tab, graf.
Abstract:
A handy device for testing the thermal sensibility of skin lesions has been developed and field tested in various centres in Africa and India. The instrument performed satisfactorily and its use made testing for thermal sensibility in the field practicable and straightforward. Analysis of the results of testing 260 persons, most of whom exhibited a few lesions that were characteristic of early leprosy, showed that the rate of diagnosis of sensory impairment of such skin lesions, and hence the diagnosis of leprosy, would be about 15-25% more if thermal sensibility testing using this device were added to the other tests of sensibility routinely carried out in the field. Regular use of the device in the field would help to bring more leprosy patients under treatment than at present.(AU).
Descriptors:
HANSENIASE/diag
HANSENIASE/fisiopatol
PROJETOS PILOTO
CALOR
AFRICA
SENSACAO
SENSIBILIDADE E ESPECIFICIDADE
PELE/inerv
Limits:
HUMANO
SUPPORT, NON-U.S. GOV'T
Electronic Medium:
http://www.ilsl.br
Location:
BR191.1; 02112/s
5 / 8
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Id:
11274
Author:
Facer, Paul; Mann, Dawn; Mathur, Rajeev; Pandya, Shubha; Ladiwalla, Uma; Singhal, Bhim; Hongo, Jo-Anne; Sinicropi, Dominick V; Terenghi, Giorgio; Anand, Praveen
Title:
Do nerve growth factor-related mmechanisms contribute to loss of cutaneous nociception in leprosy? ..-
Source:
s.l; s.n; 2000. 8 p. ilus, graf.
Descriptors:
AXONIOS
CALOR
IMUNOHISTOQUIMICA
HIBRIDIZAÇAO IN SITU
CERATINOCITOS
HANSENIASE
HANSENIASE
HANSENIASE
NOCICEPTORES
DOR
DOR
DOR
LIMIAR DA DOR
ESTIMULAÇAO FISICA
RECEPTOR DA PROTEINA TIROSINAQUINASE
REFLEXO
PELE
PELE
CANAIS DE SODIO
TIOLÉSTER HIDROLASES
VASODILATAÇAO
FATORES DE CRESCIMENTO NEURAL/ME/*PH
Location:
BR191.1; 07450/s
6 / 8
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Id:
10063
Author:
Facer, P; Mathur, R; Pandya, S. S; Ladiwala, U; Singhal, B. S; Anand, P
Title:
Correlation of quantitative tests of nerve and target organ dysfunction with skin immunohistology in leprosy ..-
Source:
s.l; s.n; 1998. 9 p. ilus, tab, graf.
Descriptors:
HANSENIASE
HANSENIASE
HANSENIASE
SISTEMA NERVOSO AUTONOMO
BIOPSIA
CALOR
IMUNOHISTOQUIMICA
FIBRAS NERVOSAS
FIBRAS NERVOSAS
SISTEMA NERVOSO
SISTEMA NERVOSO
SENSAÇAO
LIMIAR SENSORIAL
PELE
PELE
PELE
PELE
GLANDULAS SUDORIPARAS
TIOLÉSTER HIDROLASES
Location:
BR191.1; 07028/s
7 / 8
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Id:
9673
Author:
Blair, Andrea L; Cree, Ian A; Beck, John Swanson; Grange, John M; Kardijito, Thomas
Title:
Heat-stable opsonins in tuberculosis and leprosy ..-
Source:
s.l; s.n; 1993. 8 p. ilus, tab, graf.
Descriptors:
ADOLESCENCIA
ANTICORPOS ANTIBACTÉRIAS
QUIMIOLUMINESCENCIA
ELISA
CALOR
HANSENIASE
MONOCITOS
OPSONINAS
FAGOCITOSE
TUBERCULOSE
Location:
BR191.1; 06677/s
8 / 8
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Id:
9384
Author:
Mistry, Yasmin; Young, Douglas B; Mukherjee, Rama
Title:
hsp70 synthesis in schwann cells in response to heat shock and infection with Mycobacterium leprae ..-
Source:
s.l; s.n; 1992. 6 p. ilus.
Descriptors:
CALOR
PROTEINAS DO CHOQUE TÉRMICO
HANSENIASE
HANSENIASE
MACACA MULATTA
CAMUNDONGOS
CAMUNDONGOS ENDOGAMICOS BALB C
FAGOCITOSE
CÉLULAS DE SCHWANN
CELULAS CULTIVADAS
Limits:
ANIMAL
Location:
BR191.1; 06420/s
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