Database : HANSEN
Search on : GLOMERULONEFRITE/ETIOL [Subject descriptor]
References found : 4 [refine]
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Id:13368
Author:Chugh, K. S; Damle, P. B; Kaur, S; Sharma, B. K; Kumar, B; Sakhuja V; Nath I. V; Datta B. N
Title:Renal lesions in leprosy amongst north Indian patients ..-
Source:s.l; s.n; nov. 1983. 5 p. ilus, tab.
Abstract:Sixty consecutive patients with leprosy were investigated for renal involvement. Clinically overt renal disease was present in 4 patients; 3 presented with a nephrotic state and one patient with progressive renal failure. Urinalysis showed daily protein loss ranging from 0.4 to 8.9 g in 8 patients and microscopic haematuria in 4 cases. Elevated levels of blood urea and creatinine were seen only in one patient with diffuse proliferative glomerulonephritis. Of the 36 patients in whom distal tubular functions were evaluated, concentration and/or acidification defects were detected in 9 patients (25%). Renal histology revealed no abnormality in any of these patients. Serum C3 levels were decreased in 5 patients with lepromatous leprosy and 3 patients with borderline leprosy. Histological evidence of renal involvement was detected in 9 patients (15%). Amyloid deposits were seen in 3 (5%) patients of whom 2 had lepromatous leprosy and one had tuberculoid leprosy with chronic trophic ulcers. Mesangial proliferative lesions were seen in 5 (8.3%) and diffuse proliferative lesions (with crescents in more than 70% of glomeruli) in one patient. All of them had lepromatous leprosy. Three of the 5 patients with mesangial proliferative glomerulonephritis had erythema nodosum leprosum at the time of biopsy. Immunofluorescence studies revealed granular deposits of IgA, IgM and C3 in one patient with mesangial proliferation and IgA/IgM with or without C3 in 3 more patients in whom renal histology was normal. Glomerulonephritis associated with leprosy appears to be immune mediated but confirmation requires identification of lepra antigen in the glomerular immune complex deposits.(AU).
Descriptors:AMILOIDOSE/etiol
ERITEMA NODOSO
GLOMERULONEFRITE/etiol
NEFROPATIAS/etiol
TUBULOS RENAIS
HANSENIASE/compl
Limits:HUMANO
MASCULINO
FEMININO
ADULTO
MEIA-IDADE
ADOLESCENTE
Electronic Medium:http://www.ilsl.br
Location:BR191.1; 01801/s


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Id:13312
Author:Gupta, S. C; Bajaj, A. K; Govil, D. C; Sinha, S. N; Kumar, R
Title:A study of percutaneous renal biopsy in lepromatous leprosy ..-
Source:s.l; s.n; apr. 1981. 6 p. ilus, tab.
Abstract:Twenty one patients of lepromatous leprosy were investigated for evidence of renal diseases. Histological lesions were observed in 76 percent cases. Sixty two percent of the cases showed a proliferative type of glomerulonephritis. Amyloidosis was present in 14 percent. The remaining 24 percent had either non-specific changes confined to renal tubules or were normal.(AU).
Descriptors:RIM
AMILOIDOSE/etiol
AMILOIDOSE/patol
BIOPSIA
GLOMERULONEFRITE/etiol
GLOMERULONEFRITE/patol
GLOMERULOS RENAIS/patol
HANSENIASE/compl
HANSENIASE/patol
Limits:HUMANO
Electronic Medium:http://www.ilsl.br
Location:BR191.1; 00768/s


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Id:13288
Author:Drutz, David J; Gutman, Robert A
Title:Renal manifestations of leprosy: glomerulonephritis, a complication of erythema nodosum leprosum ..-
Source:s.l; s.n; july 1973. 7 p. tab, graf.
Abstract:Although Mycobacterium leprae does not invade the reanl parenchyma, there are many reports of nephritis in patients leprosy. Glomerulonephritis has been observed in autopsy studies, but the relationship to leprosy has never been clearly estabilished. In the present study, we found urinary abnormalities consistent with glomerulonephritis in 11 of 636 leprosarium inhabitants; there was a strong correlation with a history aof erythema nodosum leprosum (ENL). Seven of 8 noninstitutionalizes patients with active ENL aldo had urinary findings suggestive of glomerunephritis. In 2 patients with ENL, 1 of whom had alterations of serum complement suggestive of complement consumption, renal biopsies revealed proliferative glomerulonephritis. ENL has been considered to reflect, in part, the deposition of circulating immune complexes throught the body. These studies suggest that patients with lepromatous leprosy may expreience glomerulonephritis as one manifestation of ENL, and are consistent with recent observations of immne complex deposition in the glomerular capillary walls of the kidneys of patients with leprosy.(AU).
Descriptors:CREATININA/sangue
ERITEMA NODOSO/compl
GLOMERULONEFRITE/sangue
GLOMERULONEFRITE/etiol
GLOMERULONEFRITE/patol
HEMATURIA/etiol
HANSENIASE/compl
HANSENIASE/quimioter
HANSENIASE/imunol
HANSENIASE/patol
FORMOSA
Limits:HUMANO
MASCULINO
ADULTO
MEIA-IDADE
IDOSO
ADOLESCENTE
Electronic Medium:http://www.ilsl.br
Location:BR191.1; 00514/s


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Id:9168
Author:Rodriguez, Gerzain; Berrio, Joaquin; Sarmiento, Ladys
Title:La lepra y el rinon ?-
Source:Bogota; s.n; 1999. 11 p. ilus, graf.
Descriptors:HANSENIASE
RIM
AMILOIDOSE
GLOMERULONEFRITE
Location:BR191.1; 06122/s



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