Database : HANSEN Search on : TESTICULO/PATOL [Subject descriptor] References found : 8 [refine] Displaying: 1 .. 8   in format [Detailed]

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Id: 13701 Author: Singh, Navjeevan; Arora, V. K; Jain, Annu; Bhattacharya, S. N; Bhatia, Arati Title: Cytology of testicular changes in leprosy ..- Source: s.l; s.n; 2002. 5 p. ilus, tab. Abstract: OBJECTIVE: To study the changes in testicular aspirates and semen of patients with leprosy. STUDY DESIGN: A prospective study of 56 patients in the reproductive-age group, with no record of treatment for leprosy. Both Ridley-Jopling and WHO classification systems were used. Skin and/or nerve biopsies were performed for documentation of the diagnosis. Semen analysis and fine needle aspirates of the testes were performed. Smears from the testicular aspirates were stained with May-Grünwald-Giemsa and Ziehl-Neelsen stain. RESULTS: Five patients were unable to produce an ejaculate. Abnormal semen analysis and/or testicular aspirates were seen in 24 (42.8 per cent) patients. Eleven had oligospermia and eight azoospermia. Abnormalities in testicular aspirates ranged from hypospermatogenesis (4) through maturation arrest (1) and atrophy (11). Two patients had hydrocoele, and two had associated microfilariae. Three patients with multibacillary leprosy had type 2 reaction. Mycobacterium lepre was demonstrable in testicular aspirates from all patients with multibacillary and in three with paucibacillary leprosy. CONCLUSION: Abnormal semen analysis and/or testicular aspirates occur in a very high percentage of patients with leprosy. While this is expected for multibacillary disease, the high incidence in the paucibacillary form was surprising. With the rapid elimination of leprosy, fertility-related disability might emerge as a major problem in these people. (AU). Descriptors: BIOPSIA POR AGULHA HANSENIASE/microbiol HANSENIASE/patol SÊMEN/citol ESPERMATOGÊNESE TESTICULO/patol Limits: HUMANO MASCULINO ADULTO Electronic Medium: http://www.ilsl.br Location: BR191.1; 09008/s

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Id: 13553 Author: Dash, R. J; Samuel, E; Kaur, S; Datta, B. N; Rastogi, G. K Title: Evaluation of male gonadal function in leprosy ..- Source: s.l; s.n; july 1978. 01 p. tab. Abstract: Impotency, sterility, loss of libido, loss of sexual hair and gynecomastia are well documented in patients suffering from leprosy. They occur with greater frequency in lepromatous leprosy as compared to dimorphous and tuberculois types.(AU). Descriptors: HORMÔNIO FOLICULO ESTIMULANTE/sangue GINECOMASTIA/fisiopatol IMPOTÊNCIA/etiol INFERTILIDADE MASCULINA/etiol HANSENIASE/fisiopatol TESTICULO/patol TESTICULO/fisiopatol Limits: ESTUDO COMPARATIVO HUMANO MASCULINO Electronic Medium: http://www.ilsl.br Location: BR191.1; 0712/s

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Id: 13237 Author: Kumar B;; Raina, A; Kaur, S; Dash, R. J; Samuel, E; Datta, B. N Title: Clinico-pathological study of testicular involvement in leprosy ..- Source: s.l; s.n; jan. 1982. 8 p. ilus. Abstract: Twenty five patients of lepromatous leprosy were studied clinically and histopathologically for testicular involvement. Testicular pain or swelling was the commonest complaint (68%) followed by sterility (28%) and impotence (4%). Reduced testicular size associated with soft feel was observed in 76% patients. Gynaecomastia was present in 36% and altered sexual hair pattern in 24%. Eleven out of sixteen (69%) patients had oligo/azoospermia. Out of the twenty testicular biopsies 15 (75%) had definite histological evidence of leprous pathology, irrespective of testicular size, semen picture and clinical signs and symptoms. One out of three epididymal biopsies showed minimal changes. Histopathological changes varied markedly, it was not possible to categorize these into vascular, interstitial and obliterative phases.(AU). Descriptors: HANSENIASE/compl HANSENIASE/imunol HANSENIASE/patol ATROFIA CELULAS INTERSTICIAIS DO TESTICULO/patol ORQUITE/etiol ORQUITE/imunol ORQUITE/patol TUBULOS SEMINIFEROS/patol TESTICULO/patol Limits: HUMANO MASCULINO ADULTO MEIA-IDADE IDOSO ADOLESCENTE Electronic Medium: http://www.ilsl.br Location: BR191.1; 02145/s

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Id: 13221 Author: Morley, John E; Distiller, Larry A; Sagel, Julius; Kok, S. H; Kay, Graham; Carr, Peter; Katz, Maurice Title: Hormonal changes associated with testicular atrophy and gynaecomastia in patients with leprosy ..- Source: s.l; s.n; apr. 1977. 5 p. graf. Abstract: Basal LH, FSH, 17 beta-oestradiol and testosterone and the gonadotrophin responses to luteinizing hormone releasing hormone (LHRH) were studied in male patients with leprosy (twenty-four with lepromatous and six with tuberculoid leprosy). The mean basal LH and FSH was significantly elevated in the lepromatous group and was associated with an excessive response of both gonadotrophins following LHRH administration. The mean basal testosterone and 17 beta-oestradiol values in the lepromatous group were significantly lower than those of the tuberculoid and control groups. The abnormal gonadotrophin and sex steroid values in the lepromatous group are in keeping with the testicular atrophy and gynaecomastia accompanying this form of leprosy. However, the lack of a significant correlation between basal FSH and testicular atrophy should be noted. In addition, no correlation between any of these hormonal values and gynaecomastia could be demonstrated. The patients with tuberculoid leprosy had essentially normal hormonal profiles (except for two who had raised 17 beta-oestradiol values). This is compatible with the lack of gonadal involvement in these patients.(AU). Descriptors: ESTRADIOL/sangue HORMÔNIO FOLICULO ESTIMULANTE/sangue HANSENIASE/compl GINECOMASTIA/etiol LH/sangue DOENCAS TESTICULARES/etiol TESTICULO/patol TESTOSTERONA/sangue GONADORELINA/farmacol Limits: ESTUDO COMPARATIVO HUMANO MASCULINO ADULTO ADOLESCENTE Electronic Medium: http://www.ilsl.br Location: BR191.1; 01584/s

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Id: 13220 Author: Rees, R. J; McDougall, A. C;; Weddell, A. G Title: The testis in mice infected with Mycobacterium leprae ..- Source: s.l; s.n; feb. 1975. 7 p. ilus, tab. Abstract: Following inoculation either locally or intravenously with Mycobact. leprae of human origin, the histopathology and bacteriology of the testis in experimental mice is described. Normal mice, and mice rendered immunologically deficient by thymectomy and whole-body irradiation, were studied. Attention is drawn to a heavy bacillation of the testis in mice from both groups. Bacilli were found in and beneath the tunica albuginea, but mainly in interstitial cells and in macrophages surrounding the tubules. The percentage of solidly staining bacilli was high, and globi were frequent. The study showed that the testis in mice is particularly favourable for the lodgement and multiplication of Mycobact. laprae following either local or intravenous inoculation. The significance of this in relation to the metabolism of the leprosy bacillus and to the frequent occurrence of testicular damage in the lepromatous male patient is discussed. This work was supported by grants to A. G. M. Weddell and A. C. McDougall from the Medical Research Council and the British Leprosy Relief Association (LEPRA).(AU). Descriptors: HANSENIASE/microbiol HANSENIASE/patol IMUNOSSUPRESSAO CAMUNDONGOS ENDOGÂMICOS CBA CAMUNDONGOS NUS MYCOBACTERIUM LEPRAE/isol TESTICULO/microbiol TESTICULO/patol TIMECTOMIA IMUNIDADE/ef rad Limits: ANIMAL MASCULINO CAMUNDONGOS Electronic Medium: http://www.ilsl.br Location: BR191.1; 01582/s

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Id: 11893 Author: Singh, Navjeevan; Arora, V. K; Jain, Annu; Bhattacharya, S. N; Bhatia, Arati Title: Cytology of testicular changes in leprosy ..- Source: s.l; s.n; 2002. 5 p. ilus, tab, graf. Descriptors: HANSENIASE HANSENIASE BIOPSIA POR AGULHA SEMEN ESPERMATOGENESE TESTICULO Location: BR191.1; 08569/s

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Id: 10321 Author: Saporta, L; Yuksel, A Title: Androgenic status in patients with lepromatous leprosy ..- Source: s.l; s.n; 1994. 4 p. graf. Descriptors: ADOLESCENCIA ATROFIA DOENÇA CRONICA ESTRADIOL FSH INFERTILIDADE MASCULINA LH HANSENIASE LEPROMATOSA HANSENIASE LEPROMATOSA HANSENIASE LEPROMATOSA TESTICULO TESTOSTERONA Location: BR191.1; 06963/s

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Id: 10109 Author: Ishikawa, Satoshi; Tanaka, Hiroyuki; Mizushima, Mutsue; Hashizume, Hiroyuki; Ishida, Yutaka; Inoue, Hajime Title: Osteoporosis due to testicular atrophy in male leprosy patients ..- Source: s.l; s.n; 1997. 5 p. ilus, tab. Descriptors: ATROFIA DENSIDADE OSSEA ESTRADIOL LH HANSENIASE OSTEOPOROSE TESTICULO TESTOSTERONA Location: BR191.1; 07050/s

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