Database : HANSEN
Search on : HIPERSENSIBILIDADE A DROGAS [Subject descriptor]
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Id:17346
Author:Leta, Graziela Carneiro; Simas, Maria Esther Paes de Almeida dos Santos; Oliveira, Maria Leide W. de; Gomes, Maria Katia.
Title:Sindrome de hipersensibilidade a dapsona: revisao sistematica dos criterios diagnosticos / Dapsone hypersensitivity syndrome: a systematic review of diagnostic criteria
Source:Hansen. Int;28(1):79-84, jan.-jun. 2003. tab.
Abstract:A importancia mundial da farmacovigilancia vem aumentando, mesmo nos paises subdesenvolvidos. Neste contexto, a sindrome de hipersensibilidade a dapsona (SHD), um efeito colateral raro e potencialmente grave, deve ser considerada, sem, entretanto, comprometer a seguranca da droga e sua ampla utilizacao. Objetivando padronizar os criterios diagnosticos da sindrome, realizou-se uma revisao sistematica da literatura analisando trabalhos, publicados de quinze paises endemicos entre 1956 e 2001. Cento e oito casos foram reportados neste periodo, destes 96,2% apos 1980, com 13,3% de obitos. Neste grupo, 59% apresentaram a sindrome completa - febre, rash, linfadenopatia e hepatite, enquanto 41% expressaram forma incompleta. A taxa de mortalidade do grupo que preenche os criterios de SHD completa foi 9,6% e nao houve associacao estatistica com injuria hepatica. Todavia ressalta-se pouca qualidade dos dados coletados, o que reforca a necessidade de relatos mais precisos em futuras publicacoes. (AU).
Descriptors:DAPSONA/ef adv
HANSENIASE/compl
HANSENIASE/terap
SINDROME
 HIPERSENSIBILIDADE A DROGAS/clas
 HIPERSENSIBILIDADE A DROGAS/diag
 HIPERSENSIBILIDADE A DROGAS/fisiopatol
Electronic Medium:http://hansen.bvs.ilsl.br/textoc/hansenint/v21aov29/2003/PDF/v28n1/v28n1a08.pdf / pt
Location:BR191.1


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Id:13444
Author:Tomecki, Kenneth J; Catalano, Charles J
Title:Dapsone hypersensitivity ..-
Source:s.l; s.n; jan. 1981. 2 p. .
Abstract:A hypersensitivity reaction to low-dose (50-mg), short-term dapsone administration developed in a 16-year-old girl. The reaction included fever, malaise, dermatitis, jaundice with hepatic dysfunction, lymphadenopathy, and hemolytic anemia. Physicians should be familiar with this sulfone syndrome, an uncommon, potentially serious, side effect of dapsone therapy.(AU).
Descriptors:ACNE VULGAR/quimioter
ANEMIA HEMOLITICA/etiol
DAPSONA/ef adv
ERUPCAO POR DROGA/etiol
HIPERSENSIBILIDADE A DROGAS/diag
HEPATITE TOXICA/etiol
DOENCAS LINFATICAS/ind quim
SINDROME
Limits:RELATO DE CASO
HUMANO
FEMININO
ADOLESCENTE
Electronic Medium:http://www.ilsl.br
Location:BR191.1; 00741/s


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Id:13263
Author:Tomecki, Kenneth J; Catalano, Charles J
Title:Dapsone hypersensitivity ..-
Source:s.l; s.n; jan. 1981. 2 p. .
Abstract:A hypersensitivity reaction to low-dose (50-mg), short-term dapsone administration developed in a 16-year-old girl. The reaction included fever, malaise, dermatitis, jaundice with hepatic dysfunction, lymphadenopathy, and hemolytic anemia. Physicians should be familiar with this sulfone syndrome, an uncommon, potentially serious, side effect of dapsone therapy.(AU).
Descriptors:ACNE VULGAR/quimioter
ANEMIA HEMOLITICA/etiol
DAPSONA/ef adv
ERUPCAO POR DROGA/etiol
HIPERSENSIBILIDADE A DROGAS/diag
HEPATITE TOXICA/etiol
DOENCAS LINFATICAS/ind quim
SINDROME
Limits:RELATO DE CASO
HUMANO
FEMININO
ADOLESCENTE
Electronic Medium:http://www.ilsl.br
Location:BR191.1; 00724/s


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Id:11894
Author:Flageul, B; Wagner, L; Cottenot, F
Title:Accidents immuno-allergiques à la rifampicine ..-
Source:s.l; s.n; 2002. 8 p. tab.
Descriptors:HANSENIASE
HANSENIASE DIMORFA
HANSENIASE LEPROMATOSA
HANSENIASE TUBERCULOIDE
RIFAMPINA
RIFAMPINA
RIFAMPINA
RIFAMPINA
SULFONAMIDAS
SULFONAMIDAS
TROMBOCITOPENIA
TROMBOCITOPENIA
ANTIBIOTICOS COMBINADOS
CLOFAZIMINA
CLOFAZIMINA
DAPSONA
DAPSONA
HIPERSENSIBILIDADE A DROGAS
LEPROSTATICOS
LEPROSTATICOS
LEPROSTATICOS
Location:BR191.1; 08568/s


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Id:10366
Author:Chogle, Arun; Nagral, Aabha; Soni, Abhay; Agale, Sachin; Jamadar, Zakir
Title:Dapsone hypersensitivity syndrome with coexisting acute hepatitis E ..-
Source:s.l; s.n; 2000. 2 p. .
Descriptors:DOENÇA AGUDA
ADOLESCENCIA
ANTIINFLAMATORIOS ESTEROIDES
DAPSONA
DAPSONA
HIPERSENSIBILIDADE A DROGAS
HEPATITE E
LEPROSTATICOS
LEPROSTATICOS
HANSENIASE
HANSENIASE
PREDNISOLONA
SINDROME
Limits:RELATO DE CASO
Location:BR191.1; 07498/s


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Id:10021
Author:Dhamija, R; Kumar, D; Khurana, G
Title:Dapsone syndrome ..-
Source:s.l; s.n; 1995. 2 p. .
Descriptors:DAPSONA
DIAGNOSTICO DIFERENCIAL
HIPERSENSIBILIDADE A DROGAS
HIPERSENSIBILIDADE A DROGAS
HIPERSENSIBILIDADE A DROGAS
HEPATITE TOXICA
LEPROSTATICOS
HANSENIASE
SINDROME
Location:BR191.1; 06986/s


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Id:9544
Author:Roche, Paul W; Theuvenet, Wim J; Britton, Warwick J
Title:Risk factors type-1 reactions in bordeline leprosy patients ..-
Source:s.l; s.n; 1991. 4 p. tab, graf.
Descriptors:ADOLESCENCIA
ANTICORPOS ANTIBACTÉRIAS
ANTICORPOS MONOCLONAIS
MARCADORES BIOLOGICOS
HIPERSENSIBILIDADE A DROGAS
HIPERSENSIBILIDADE A DROGAS
IMUNIDADE CELULAR
TESTES INTRADÉRMICOS
HANSENIASE DIMORFA
HANSENIASE DIMORFA
HANSENIASE TUBERCULOIDE
LIPOPOLISSACARIDIOS
MYCOBACTERIUM LEPRAE
NEURITE
NEURITE
DOENÇAS DO SISTEMA NERVOSO PERIFÉRICO
DOENÇAS DO SISTEMA NERVOSO PERIFÉRICO
FATORES DE RISCO
GLICOLIPIDIOS
Location:BR191.1; 06272/s


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Id:9232
Author:Cabrera, Hugo N; Valente, Enrique; Gallegos, Maria Cecilia; Garcia, Sandra M
Title:Sindrome de hipersensibilidad a la dapsona ?-
Source:s.l; s.n; 1997. 4 p. ilus.
Descriptors:DAPSONA
DAPSONA
LEPROSTATICOS
HANSENIASE LEPROMATOSA
HIPERSENSIBILIDADE
HIPERSENSIBILIDADE A DROGAS
HIPERSENSIBILIDADE A DROGAS
Limits:RELATO DE CASO
HUMANO
MASCULINO
MEIA-IDADE
Location:BR191.1; 06100/s


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Id:9177
Author:Rotman, Leandro; San Martin, Sara; Blasina, Elena N; Desiderio, Cristina E; Furcenko, Ana; Rizzo, Liliana; Pissano, Maria Noemi; Zahr, Ines
Title:Insuficiencia renal aguda por rifampicina en dos pacientes de hanseniasis multibacilar ?-
Source:s.l; s.n; 1997. 4 p. .
Descriptors:HIPERSENSIBILIDADE A DROGAS
HANSENIASE
RIFAMPINA
RIFAMPINA
RIFAMPINA
INSUFICIENCIA RENAL AGUDA
INSUFICIENCIA RENAL AGUDA
Location:BR191.1; 06144/s


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Id:7644
Author:Fader, Darrel J; Johnson, Timothy M
Title:Medical issues and emergencies in the dermatology office ..-
Source:s.l; s.n; 1997. 16 p. ilus, tab.
Abstract:We review the medical issues and emergencies potentially encountered in the practice of general or surgical dermatology. Traditional guidelines have largely consisted of dated extrapolations from the nondermatologic literature concerning procedures that are primarily irrelevant to dermatology. This article outlines a rational approach to organizing an office emergency plan for anaphylaxis, stroke, status epilepticus, myocardial infarction, and hypertensive crisis. We discuss the literature that has influenced current office behavior regarding endocarditis prophylaxis, the use of electrosurgery with pacemakers, arrhythmogenic drug interactions, vasovagal syncope, lidocaine "allergy," and bleeding complications from oral anticoagulants. Recommendations for managing these issues in a dermatologic context are provided..
Descriptors:ANTICOAGULANTES/efeitos adversos
TRANSTORNOS CEREBROVASCULARES/terapia
DERMATOLOGIA
DOENCA
INTERACOES DE MEDICAMENTOS
HIPERSENSIBILIDADE A DROGAS/etiologia
HIPERSENSIBILIDADE A DROGAS/terapia
ELETROCIRURGIA/efeitos adversos
EMERGENCIAS
SERVICOS MEDICOS DE EMERGENCIA
ENDOCARDITE BACTERIANA/prevenção e controle
DIRETRIZES
HEMORRAGIA/terapia
HIPERTENSAO/terapia
LIDOCAINA/efeitos adversos
INFARTO DO MIOCARDIO/terapia
MARCA-PASSO ARTIFICIAL
CONSULTORIOS MEDICOS
DERMATOPATIAS/cirurgia
DERMATOPATIAS/terapia
ESTADO EPILEPTICO/terapia
SINCOPE/terapia
Limits:HUMANO
Location:BR191.1; 0194/cme



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