Database : HANSEN Search on : IMUNOGLOBULINAS [Subject descriptor] References found : 25 [refine] Displaying: 1 .. 20   in format [Detailed]

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Id: 19683 Author: Argumedo, Leopoldo Santos; Infante, Fernando Guerra; Pascual, Fausto Quesada; Parra, Sergio Estrada. Title: Identification and Purification of Armadillo (Dasypus novemcinctus) Immunoglobulins: Preparation of Specific Antisera to Evaluate the Immune Response in These Animals. Source: Int. J. Lepr;63(1):56-61, 1995. ^bilus, ^btab, ^bgraf. Abstract: Resumo: In this work we describe the purification and characterization of armadillo immunoglobulins. The IgM was precipitated using low-strength ionic solution and further purified by filtration through Sephadex G-200. The IgG was obtained in pure form by precipitation of serum with ammonium sulfate and DEAE-cellulose ion exchange chromatography. The purity of these immunoglobulins was evaluated by polyacrylamide gel electrophoresis. The results showed 28-kDa light chains and 55-kDa and 70-kDa heavy chains for IgG and IgM, respectively. The rabbit antibodies against these molecules were used to prepare fluorescein (FITC) and peroxidase conjugates. The FITC conjugate was used to quantify IgM-bearing lymphocytes. An average of 17% of peripheral blood lymphocytes were sIgM+ from 14 healthy animals. Additionally, in the same animals we quantified lymphocytes with the capacity to form rosettes with sheep red-blood cells; the average for this marker was 10%. Also, the production of crossreacting antibodies to BCG was evaluated in healthy and Mycobacterium leprae-inoculated animals using the peroxidase conjugates. All animals with active infection recognized BCG antigens. Descriptors: Imunoglobulinas/anal Imunoglobulinas/imunol Tatus/genet Electronic Medium: http://hansen.bvs.ilsl.br/textoc/revistas/intjlepr/1995/pdf/v63n1/v63n1a09.pdf / en Location: BR191.1

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Id: 19602 Author: Rojas-Espinosa, Oscar; Oltra, Antonina; Arce, Patricia; Mendez, Patricia. Title: Glomerular immunoglobulin deposition in the absence of tissue damage in murine leprosy. Source: Int. J. Lep;57(4):879-882, dec. 1989. . Descriptors: Hanseníase/imunol Hanseníase/microbiol Imunoglobulinas/anal Imunoglobulinas/imunol Limits: Animais Camundongos Electronic Medium: http://hansen.bvs.ilsl.br/textoc/revistas/intjlepr/1989/pdf/v57n4/v57n4cor07.pdf / en Location: Br191.1

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Id: 18351 Author: Shuttleworth, J. S; Ross, S. H Title: Secondary amyloidosis in leprosy ?- Source: s.l; s.n; 1956. 16p p. . Abstract: Secondary amyloidosis is the leading cause of death in lepromatous leprosy in this country. The mortality is directly caused by amyloid involvement of the kidneys, which occurred in 100% of this series. The diagnosis of this complication depends largely on the development of a persistent proteinuria, Congo red absorption, hepatosplenomegaly and, to a lesser degree, altered serum proteins and perhaps liver biopsy in selected cases. the correlation between the Congo red test and the degree of amyloidosis is poor, and unless this test shows 80 to 100% dye absorption in one hour the diagnosis cannot be made from this finding alone. Serum protein and lipoid changes occur in lepromatous leprosy per se, and in a study of the various protein fractions no consistent alteration occurred in cases complicated by amyloidosis. The average duration of life after the onset of proteinuria in amyloidosis was 38.33 months, with a fairly wide range above and below this figure. The development of anemia and a progressive elevation of the nonprotein nitrogen are unfavorable prognostic signs. Descriptors: HANSENIASE/clas HANSENIASE/compl AMILOIDOSE/sangue AMILOIDOSE/diag AMILOIDOSE/etiol AMILOIDOSE/imunol VERMELHO CONGO/uso diag - ALBUMINURIA/etiol  ALBUMINURIA/epidemiol  IMUNOGLOBULINAS/anal  IMUNOGLOBULINAS/sangue Limits: HUMANO Location: BR191.1; 01797/s

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Id: 17275 Author: Bleharski, Joshua R; Li, Huiying; Meinken, Cristoph; Graeber, Thomas G; Ochoa, Maria-Teresa; Yamamura, Masahiro; Burdick, Anne; Sarno, Euzenir N; Wagner, Manfred; Röllinghoff, Martin; Rea, Thomas H; Colonna, Marco; Stenger, Steffen; Bloom, Barry R; Eisenberg, David; Modlin, Robert L Title: Use of genetic profiling in leprosy to discriminate clinical forms of the disease ..- Source: s.l; s.n; 2003. 4 p. . Abstract: Leprosy presents as a clinical and immunological spectrum of disease. With the use of gene expression profiling, we observed that a distinction in gene expression correlates with and accurately classifies the clinical form of the disease. Genes belonging to the leukocyte immunoglobulin-like receptor (LIR) family were significantly up-regulated in lesions of lepromatous patients suffering from the disseminated form of the infection. In functional studies, LIR-7 suppressed innate host defense mechanisms by shifting monocyte production from interleukin-12 toward interleukin-10 and by blocking antimicrobial activity triggered by Toll-like receptors. Gene expression profiles may be useful in defining clinical forms of disease and providing insights into the regulation of immune responses to pathogens. (AU). Descriptors: Algoritmos Análise por Conglomerados Contagem de Colônia Microbiana Citocinas/GE/ME Perfilação da Expressão Gênica/* Regulação da Expressão Gênica/* Genes de Imunoglobulinas Imunidade Celular Imunidade Natural Hanseníase Virchowiana/*CL/*GE/IM/PP Hanseníase Tuberculóide/*CL/*GE/IM/PP Macrófagos Alveolares/MI Glicoproteínas de Membrana/IM Mycobacterium tuberculosis/GD/IM Análise de Sequência com Séries de Oligonucleotídeos Reação em Cadeia da Polimerase Análise de Componente Principal Receptores da Superfície Celular/IM Receptores Imunológicos/GE/ME Limits: Humano Support, Non-U.S. Gov't Support, U.S. Gov't, P.H.S. Regulação para Cima Location: BR191.1; 09174/s

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Id: 13879 Author: Tarabini-Castellani, G; Tarabini-Castellani, G. L; Gasparolo, A; Toffolutti, M; De Luca, R; Santini, G. F. Title: Relación entre albúminas e inmunoglobulinas séricas y licuorales en hanseniano. Source: Fontilles - Revista de Leprología;18(3):249-280, Sep.-Dic. 1991. tab, graf. Abstract: Los resultados de mayor interés obtenidos sobre las muestras de LCD y suero de 7 casos de hanseniasis (H.D.) (2 borderline: B 3 lepromatosos: L de los cuales el 4 L grave y con déficit inmunitario; 2 tuberculoides: T), son: I.º) Los índices LCR/suero de la albúmina y de las IgG por tests cinético-nefelometría y de las IgG anti PGL-1 por ELISA, en cuanto separan los casos según sus tipos y forma mediante valores típicamente uniformes: los más bajos de albúmina para los L; los más bajos de IgG anti PGL-1 para los B; los medios de IgG para los T, siendo los B y L muy deformantes. II.º) Los index de LINK indican producción intratecal de IgG si superan el V.N. en nuestros casos los de IgG anti PGL-1 han resultado todos superiores y altos, sólo los B menos altos; los IgG todos inferiores; pero, hay que considerar que por la policlonía de la IgG, una parte de ellas podría resultar superior si fuese revelada aisladamente por su antígeno específico. III.º) Una mayor casuística con test de medidas homólogas para los dos de IgG podrá confirmar o no nuestros resultados, y también modificar nuestra de ducción por la cual los epítopes HLA-DR de los queratinocitos uniéndose con las IgG intratecales determinarían la respuesta al test lepromínico, es decir, negativa en los L por la falta de los HLA-DR; positiva la precoz en los B po la unión con la IgG; positiva la tardía y a menudo la precoz en los T por la unión con la IgG anti PGL-1 y las IgG. Otro caso de diagnosis incierta resulta positivo para la H.D. de tipo T, pero atípico o la debido a la asociación de otra enfermedad del S.N.C. como la esclerosis múltiple o la siringomielía. (AU). Descriptors: HANSENIASE/terap ALBUMINAS/admin ALBUMINAS/ef adv IMUNOGLOBULINAS/clas Location: BR191.1

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Id: 13656 Author: Bleharski, Joshua R; Li, Huiying; Meinken, Christoph; Graeber, Thomas G; Ochoa, Maria-Teresa; Yamamura, Masahiro; Burdick, Anne; Sarno, Euzenir N; Wagner, Manfred; Röllinghoff, Martin; Rea, Thomas H; Colonna, Marco; Stenger, Steffen; Bloom, Barry R; Eisenberg, David; Modlin, Robert L Title: Use of genetic profiling in leprosy to discriminate clinical forms of the disease ..- Source: s.l; s.n; Sep. 2003. 4 p. graf. Abstract: Leprosy presents as a clinical and immunological spectrum of disease. With the use of gene expression profiling, we observed that a distinction in gene expression correlates with and accurately classifies the clinical form of the disease. Genes belonging to the leukocyte immunoglobulin-like receptor (LIR) family were significantly up-regulated in lesions of lepromatous patients suffering from the disseminated form of the infection. In functional studies, LIR-7 suppressed innate host defense mechanisms by shifting monocyte production from interleukin-12 toward interleukin-10 and by blocking antimicrobial activity triggered by Toll-like receptors. Gene expression profiles may be useful in defining clinical forms of disease and providing insights into the regulation of immune responses to pathogens. (AU). Descriptors: HANSENIASE VIRCHOWIANA/clas HANSENIASE VIRCHOWIANA/genet HANSENIASE VIRCHOWIANA/imunol HANSENIASE VIRCHOWIANA/fisiopatol HANSENIASE TUBERCULOIDE/clas HANSENIASE TUBERCULOIDE/genet HANSENIASE TUBERCULOIDE/imunol HANSENIASE TUBERCULOIDE/fisiopatol CITOCINAS/genet CITOCINAS/metab PERFILACAO DA EXPRESSÃO GÊNICA ANALISE POR CONGLOMERADOS CONTAGEM DE COLÔNIA MICROBIANA REGULACAO DA EXPRESSÃO GÊNICA IMUNIDADE CELULAR IMUNIDADE NATURAL MACROFAGOS ALVEOLARES/microbiol GLICOPROTEINAS DE MEMBRANA/imunol MYCOBACTERIUM TUBERCULOSIS/cresc MYCOBACTERIUM TUBERCULOSIS/imunol REACAO EM CADEIA DA POLIMERASE RECEPTORES IMUNOLOGICOS/genet RECEPTORES IMUNOLOGICOS/metab RECEPTORES DA SUPERFICIE CELULAR/imunol - REGULACAO PARA CIMA  Análise de Componente Principal  ALGORITMOS  GENES DE IMUNOGLOBULINAS  ANALISE DE SEQUÊNCIA COM SERIES DE OLIGONUCLEOTIDIOS Limits: SUPPORT, NON-U.S. GOV'T HUMANO SUPPORT, U.S. GOV'T, P.H.S. Electronic Medium: http://www.ilsl.br Location: BR191.1; 09142/s; BR191.1; 09145/s

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Id: 13595 Author: Feyeux, C; Verola, O; Bakir, R; Rouffy, J Title: Amyloïdose associée à un myélome à IGD (lambda), chez un hansénien Amyloidosis associated with IGD (lambda) myeloma in a Hansen's disease patient- Source: s.l; s.n; 1983. 2 p. ilus. Abstract: M. F.., 56 nos, portugais présentant comme antécédent une lèpre lépromateuse traitée par les sulfones de 1948 à 1958 nus est adressé pour le bilan d'une amyloidose généralisée.(AU). Descriptors: HANSENIASE/compl IMUNGLOBULINA D IMUNOGLOBULINAS CADEIA LAMBDA MIELOMA MULTIPLO/compl AMILOIDOSE/etiol Limits: RELATO DE CASO HUMANO MASCULINO MEIA-IDADE Electronic Medium: http://www.ilsl.br Location: BR191.1; 01792/s

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Id: 13594 Author: Winter, R. J; Banks, R. A; Collins, C. M; Hoffbrand, B. I Title: Rifampicin induced light chain proteinuria and renal failure ..- Source: s.l; s.n; dec. 1984. 2 p. . Abstract: Light chain proteinuria is a recognised cause of renal disease and renal failure. In 1973 Graber et al described light chain proteinuria occuring in patients given rifampicin and there have since been two case reports of renal failure due to rifampicin induced light chain proteinuria.(AU). Descriptors: DESIDRATACAO/compl IMUNOGLOBULINAS CADEIA LEVE/urina INSUFICIÊNCIA RENAL AGUDA/ind quim PROTEINURIA/ind quim RIFAMPINA/ef adv Limits: RELATO DE CASO HUMANO MASCULINO MEIA-IDADE Electronic Medium: http://www.ilsl.br Location: BR191.1; 01799/s

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Id: 13539 Author: Ramanathan, V. D; Thyagi, P; Ramanathan, U; Katoch, K; Ramu, G Title: A sequential study of circulating immune complexes, complement and immunoglobulins in borderline tuberculoid leprosy patients with and without reactions ..- Source: s.l; s.n; 1998. 8 p. tab, graf. Abstract: Sequential estimates of the levels of circulating immune complexes (CIC), complement catabolic fragment C3d, complement-mediated immune complex solubilization (CMS) and immunoglobulins were made in 24 newly diagnosed with borderline tuberculoid leprosy over a 20 month period after initiation of chemotherapy. Fourteen of these patients had not suffered from reversal reactions either at the time of presentation or during the follow-up. The levels of CIC were evaluated in them from the third to the eleventh month after starting chemotherapy and immunoglobulin G (IgG) levels were evaluated up to eight months. The concentrations of C3d and immunoglobulins A (IgA) and M (IgM) were normal in these patients. The other ten patients had reversal reaction at the time of diagnosis which subsided by the third month after starting treatment. They did not have reversal reactions later. The levels of CIC and IgG were elevated and those of CMS were depressed throughout the study period. Serum C3d level was initially elevated but came down to normal by the third month while IgA and IgM levels were within normal limits. The relevance of these findings to the genesis of reversal reaction is discussed in this communication.(AU). Descriptors: COMPLEXO ANTIGENO-ANTICORPO/sangue COMPLEMENTO 3D/anal ANTIGENO DE MITSUDA IMUNOGLOBULINAS/sangue HANSENOSTATICOS/uso terap HANSENIASE TUBERCULOIDE/quimioter HANSENIASE TUBERCULOIDE/imunol FATORES DE TEMPO Limits: HUMANO MASCULINO FEMININO ADULTO MEIA-IDADE Location: BR191.1; 09164/s

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Id: 13413 Author: Closs, O; Mshana, R. N; Harboe, M Title: Antigenic analysis of Mycobacterium leprae ..- Source: s.l; s.n; mar. 1979. 6 p. ilus. Abstract: About twenty distinct antigenic components have been demonstrated in Mycobacterium leprae (M. leprae) by crossed immunoelectrophoresis against a rabbit antiserum produced by immunization with concentrated M. leprae antigen. This system allows a more detailed analysis of the antigenic relationship between M. leprae and other mycobacteria and a better characterization of the antigenic content of various M leprae preparations than with previously available anstisera of the antigenic content of various M. leprae preparations than with previously available antisera which reacted with far fewer components. The antibody activity in sera of patients with lepromatous leprosy was studied by incorporating the sera into the intermediate gel of the M. leprae reference system. Antibodies were found against only seven of the components. Since those compared are all known to be cross-reacting widely with antigens of other mycobacteria, it is speculated that cross-immunization may influence the antibody response in lepromatous leprosy.(AU). Descriptors: IMUNOELETROFORESE BIDIMENSIONAL SOROTIPAGEM ANTIGENOS DE BACTERIAS/anal FRAGMENTOS DE IMUNOGLOBULINAS ANTICORPOS ANTIBACTERIAS MYCOBACTERIUM LEPRAE/imunol Limits: ANIMAL COELHOS Electronic Medium: http://www.ilsl.br Location: BR191.1; 00025/s

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Id: 12258 Author: Tovar-Rivera, T; Sánchez-Colón, S; Padierna-Olivos, L; Massó-Rojas, F; Estrada-Parra, S; Mondragón-González, R; Jiménez-Martínez, M. C; Sánchez-García, F. J Title: Connectivity patterns in tuberculosis and leprosy patients are indistinguishable from that of healthy donors ..- Source: s.l; s.n; 2001. 8 p. graf. Descriptors: ANTICORPOS ANTIBACTÉRIAS ANTICORPOS ANTIBACTÉRIAS ESPECIFICIDADE DE ANTICORPOS ANTIGENOS DE BACTÉRIAS IMUNOGLOBULINAS FAB ENFOQUE ISOELÉTRICO HANSENIASE MYCOBACTERIUM LEPRAE MYCOBACTERIUM TUBERCULOSIS TUBERCULOSE PULMONAR Imunoglobulina G/BI Imunoglobulina G/BI Mycobacterium tuberculosis/IM Tuberculose Pulmonar/*IM Location: BR191.1; 08691/s

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Id: 11617 Author: Tovar-Rivera, T; Sánchez-Colón, S; Padierna_olivos, L; Massó-Rojas, F; Estrada-Parra, S; Mondragón-Gonzáles, R; Jiménez-Martínez, M. C; Sánchez_garcía, F. J Title: Connectivity patterns in tuberculosis and leprosy patients are indistinguishable from that of healthy donors ..- Source: s.l; s.n; 2001. 8 p. graf. Descriptors: ANTICORPOS ANTIBACTÉRIAS ANTICORPOS ANTIBACTÉRIAS ESPECIFICIDADE DE ANTICORPOS ANTIGENOS DE BACTÉRIAS IMUNOGLOBULINAS FAB ENFOQUE ISOELÉTRICO HANSENIASE MYCOBACTERIUM LEPRAE MYCOBACTERIUM TUBERCULOSIS TUBERCULOSE PULMONAR Imunoglobulina G/BI Imunoglobulinas Fab/IM Location: BR191.1; 08440/s

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Id: 11156 Author: Medina, F; Camargo, A; Moreno, J; Zonana-Nacach, A; Aceves-Avila, J; Fraga, A Title: Anti-neutrophil cytoplasmic autoantibodies in leprosy ..- Source: s.l; s.n; 1998. 4 p. tab. Descriptors: HANSENIASE DOENÇAS AUTO-IMUNES SEDIMENTAÇAO SANGUINEA IMUNOGLOBULINAS Location: BR191.1; 07308/s

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Id: 10112 Author: Thakar, Y. S; Chande, Chhaya; Dhanvijay, A. G; Pande, Shubha; Saoji, A. M Title: Analysis of immunoglobulin deficiency cases: a five year study ..- Source: s.l; s.n; 1997. 5 p. tab. Descriptors: ADOLESCENCIA ARTRITE REUMATOIDE ATAXIA TELANGIECTASIA QUEIMADURAS ESTUDOS DE CASOS E CONTROLES CRIANÇA PRÉ-ESCOLAR IMUNOGLOBULINAS SINDROMES DE DEFICIENCIA IMUNOLOGICA LACTENTE HANSENIASE LINFOMA MALARIA MIELOMA MULTIPLO Limits: RELATO DE CASO Location: BR191.1; 07053/s

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Id: 10087 Author: Hawes, Gail E; Struyk, Linda; Beacock-Sharp, Helen; Henwood, Judy; Gaston, J. S. Hill; Van den Elsen, Peter J Title: Conserved TcR B chain usage for a single MHC class II-restricted heat shock protein peptide ..- Source: s.l; s.n; 1998. 6 p. tab, graf. Descriptors: HANSENIASE TUBERCULOIDE HANSENIASE TUBERCULOIDE SEQUENCIA DE AMINOACIDOS APRESENTAÇAO DO ANTIGENO SEQUENCIA DE BASES CHAPERONINAS CÉLULAS CLONAIS DNA ANTIGENO HLA-DR3 IMUNOGLOBULINAS CADEIA ALFA DADOS DE SEQUENCIA MOLECULAR RECEPTORES PARA ANTIGENOS DE CÉLULAS T ALFA-BETA HOMOLOGIA DE SEQUENCIA DE AMINOACIDOS LINFOCITOS T Location: BR191.1; 07146/s

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Id: 9800 Author: Schlesinger, Larry S; Horwitz, Marcus A Title: A role for natural antibody in the pathogenesis of leprosy: antibody in nonimmune serum mediates C3 fixation to the Mycobacterium leprae surface and hence phagocytosis by human mononuclear phagocytes ..- Source: s.l; s.n; 1994. 10 p. ilus, tab, graf. Descriptors: HANSENIASE HANSENIASE MYCOBACTERIUM LEPRAE MYCOBACTERIUM LEPRAE ANTICORPOS ANTICORPOS ANTIBACTÉRIAS COMPLEMENTO 1Q COMPLEMENTO 3 TESTES DE FIXAÇAO DE COMPLEMENTO VIA ALTERNATIVA DO COMPLEMENTO VIA CLASSICA DO COMPLEMENTO GLICOLIPIDIOS IMUNOGLOBULINAS LEUCOCITOS MONONUCLEARES FAGOCITOSE Location: BR191.1; 06748/s

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Id: 9716 Author: Sanchez Monton, T; Martin Luengo, F Title: Serodiagnostico en la tuberculosis pulmonar. Valoracion clinica ..- Source: s.l; s.n; 1992. 5 p. tab, graf. Descriptors: ANTICORPOS ANTIBACTÉRIAS ESPECIFICIDADE DE ANTICORPOS ANTIGENOS DE BACTÉRIAS ESTUDOS DE CASOS E CONTROLES ELISA ESTUDOS DE AVALIAÇAO IMUNOGLOBULINAS IMUNOGLOBULINAS HANSENIASE PNEUMOPATIAS MYCOBACTERIUM TUBERCULOSIS MYCOBACTERIUM TUBERCULOSIS VALOR PREDITIVO DOS TESTES SENSIBILIDADE E ESPECIFICIDADE ESCARRO TUBERCULOSE PULMONAR TUBERCULOSE PULMONAR TUBERCULOSE PULMONAR Location: BR191.1; 06514/s

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Id: 9625 Author: Xabier, Myriam Guebre; Howe, Rawleigh C; Frommel, Dominique Title: Infection et elimination de Mycobacterium leprae par la souris SCID C.B.-17 (deficit immunitaire combine severe) ..- Source: s.l; s.n; 1992. 5 p. tab, graf. Descriptors: HANSENIASE LINFOCITOS B CONTAGEM DE CÉLULAS IMUNOGLOBULINAS CONTAGEM DE LEUCOCITOS IMUNODEFICIENCIA COMBINADA SEVERA IMUNODEFICIENCIA COMBINADA SEVERA BAÇO LINFOCITOS T Limits: ANIMAL FEMININO CAMUNDONGOS Location: BR191.1; 06567/s

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Id: 9507 Author: Looi, L. M Title: The pattern of amyloidosis in a Malaysian patient population ..- Source: s.l; s.n; 1991. 9 p. ilus, tab. Descriptors: AMILOIDE AMILOIDOSE AMILOIDOSE AMILOIDOSE CRIANÇA IMUNOGLOBULINAS CADEIA KAPPA IMUNOGLOBULINAS CADEIA LAMBDA IMUNOHISTOQUIMICA MALASIA MICROSCOPIA ELETRONICA MIOCARDIOPATIAS NEOPLASIAS PERMANGANATO DE POTASSIO PREVALENCIA DERMATOPATIAS Location: BR191.1; 06363/s

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Id: 9441 Author: Zumla, A; Williams, W; Mudd, D; Locniskar, M; Behrens, R; Isenberg, D; McAdam, K. P. W. J Title: Expression of a common idiotype PR4 in the sera of patients with leprosy ..- Source: s.l; s.n; 1991. 5 p. ilus, tab. Descriptors: AUTO-ANTICORPOS IGE IGM IDIOTIPOS DE IMUNOGLOBULINAS HANSENIASE COELHOS TUBERCULOSE PULMONAR Location: BR191.1; 06319/s

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