Database : HANSEN Search on : VACINACAO [Subject descriptor] References found : 32 [refine] Displaying: 1 .. 20   in format [Detailed]

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Id: 17318 Author: Black, Gillian F; Weir, Rosemari E; Chaguluka, Steven D; Warndorff, David; Crampin, Amelia C; Mwaungulu, Lorren; Sichali, Lifted; Floyd, Sian; Bliss, Lyn; Jarman, Elizabeth; Docovan, Linda; Andersen, Peter; Britton, Warwick; Hewinson, Glyn; Huygen, Kris; Paulsen, Jean; Sing, Mahavir; Prestidge, Ross; Fine, Paul E. M; Dockrell, Hazel M Title: Gama interferon responses induced by a panel of recombinant and purified mycobacterial antigens in healthy, non-Mycobacterium bovis BCG-vaccinated Malawian young adults ..- Source: s.l; s.n; 2003. 10 p. graf. Abstract: We have previously shown that young adults living in a rural area of northern Malawi showed greater gamma interferon (IFN-gamma) responses to purified protein derivatives (PPD) prepared from environmental mycobacteria than to PPD from Mycobacterium tuberculosis. In order to define the mycobacterial species to which individuals living in a rural African population have been exposed and sensitized, we tested T-cell recognition of recombinant and purified antigens from M. tuberculosis (38 kDa, MPT64, and ESAT-6), M. bovis (MPB70), M. bovis BCG (Ag85), and M. leprae (65 kDa, 35 kDa, and 18 kDa) in >600 non-M. bovis BCG-vaccinated young adults in the Karonga District of northern Malawi. IFN-gamma was measured by enzyme-linked immunosorbent assay (ELISA) in day 6 supernatants of diluted whole-blood cultures. The recombinant M. leprae 35-kDa and 18-kDa and purified native M. bovis BCG Ag85 antigens induced the highest percentages of responders, though both leprosy and bovine tuberculosis are now rare in this population. The M. tuberculosis antigens ESAT-6 and MPT64 and the M. bovis antigen MPB70 induced the lowest percentages of responders. One of the subjects subsequently developed extrapulmonary tuberculosis; this individual had a 15-mm-diameter reaction to the Mantoux test and responded to M. tuberculosis PPD, Ag85, MPT64, and ESAT-6 but not to any of the leprosy antigens. We conclude that in this rural African population, exposure to M. tuberculosis or M. bovis is much less frequent than exposure to environmental mycobacteria such as M. avium, which have antigens homologous to the M. leprae 35-kDa and 18-kDa antigens. M. tuberculosis ESAT-6 showed the strongest association with the size of the Mantoux skin test induration, suggesting that among the three M. tuberculosis antigens tested it provided the best indication of exposure to, or infection with, M. tuberculosis. (AU). Descriptors: Antígenos de Bactérias/*IM Vacina BCG/*IM Interferon Tipo II/*BI Hanseníase/EP Malauí/EP Mycobacterium/GE/*IM Mycobacterium bovis/IM Mycobacterium leprae/IM Mycobacterium tuberculosis/IM Proteínas Recombinantes de Fusão/IM Especificidade de Espécies Linfócitos T/IM Teste Tuberculínico Tuberculose/IM Vacinação Limits: Adolescente Adulto Criança Estudo Comparativo Feminino Humano Masculino População Rural Location: BR191.1; 00224/s

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Id: 13735 Author: Ngamying, Maeya; Sawanpanyalert, Pathom; Butraporn, Raywadee; Nikasri, Junjira; Cho, Sang-Nae; Levy, Louis; Brennan, Patrick J Title: Effect of vaccination with refined components of the organism on infection of mice with Mycobacterium leprae ..- Source: s.l; s.n; 2003. 3 p. tab. Abstract: Only native products of Mycobacterium leprae, whether cell wall, cytosol, or membrane derived, can confer protective immunity against challenge in the mouse footpad. Previously, recombinant proteins were shown to be ineffective. The cell wall skeleton-the mycolyl-arabinogalactan-peptidoglycan complex-devoid of proteins is not protective. (AU). Descriptors: HANSENIASE/prev VACINAS BACTERIANAS/imunol ESQUELETO DA PAREDE CELULAR/imunol CAMUNDONGOS ENDOGÂMICOS BALB C MYCOBACTERIUM BOVIS/imunol MYCOBACTERIUM LEPRAE/imunol VACINACAO Limits: ANIMAL FEMININO CAMUNDONGOS SUPPORT, U.S. GOV'T, P.H.S. Electronic Medium: http://www.ilsl.br Location: BR191.1

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Id: 13716 Author: Vogel, Gretchen Title: Health body taps a consummate insider and disease fighter ..- Source: s.l; s.n; Feb. 2003. 1 p. ilus. Descriptors: SINDROME DE IMUNODEFICIÊNCIA ADQUIRIDA PROGRAMAS DE VACINACAO/hist HANSENIASE/hist HANSENIASE/prev SAUDE MUNDIAL ORGANIZACAO MUNDIAL DA SAUDE/org - RETRATOS Limits: HUMANO HISTORIA DA MEDICINA DO SÉCULO 20 HISTORIA DA MEDICINA DO SECULO 21 Electronic Medium: http://www.ilsl.br Location: BR191.1; 09139/s; BR191.1; 09143/s

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Id: 13544 Author: Convit, Jacinto; Ulrich, Marian Title: Recent advances in the immunology of leprosy ..- Source: s.l; s.n; apr. 1976. 14 p. ilus. Abstract: For many decades, interest in leprosy has been largely limited to those areas of the tropical and subtropical world where the disease constitutes an important public health problem.(AU). Descriptors: ANTICORPOS ANTIBACTERIAS COMPLEXO ANTIGENO-ANTICORPO REACOES ANTIGENO-ANTICORPO TECNICAS IMUNOLOGICAS HANSENIASE/quimioter HANSENIASE/imunol HANSENIASE/patol LINFOCITOS/imunol MACROFAGOS/imunol MYCOBACTERIUM LEPRAE/imunol - IMUNIZACAO PASSIVA  SINDROMES DE DEFICIÊNCIA IMUNOLOGICA/imunol  IMUNOTERAPIA  VACINACAO  IMUNIDADE  IMUNIDADE CELULAR  TATUS/imunol  MODELOS ANIMAIS DE DOENCAS Limits: HUMANO ANIMAL Electronic Medium: http://www.ilsl.br Location: BR191.1; 00578/s

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Id: 13474 Author: Shepard, Charles C; Van Landingham, Rosalind M; Walker, Laura L; Ye, Shang-Zhang Title: Comparison of the immunogenicity of vaccines prepared from viable Mycobacterium bovis BCG, heat-killed Mycobacterium leprae, and a mixture of the two for normal and M. leprae-tolerant mice ..- Source: s.l; s.n; jun. 1983. 8 p. graf. Abstract: Intradermal vaccines consisting of viable Mycobacterium bovis BCG, heat-killed Mycobacterium leprae, or mixtures of the two were titrated in mice in doses of 10(5.2), 10(5.8), 10(6.4), 10(7.0), and 10(7.6) acid-fast bacilli. The immune response was measured by sensitization (48 to 72 h foot pad enlargement on challenge with 10(7.0) heat-killed M. leprae) and by protection against infection with a viable M. leprae challenge. There was increasing response with increasing dose of vaccine, and overall the responses to the three vaccines were similar. At the lowest dose, however, the combination of BCG and M. leprae gave superior protection. The local reaction to the vaccines in the lower dose range was less severe with the M. leprae vaccine. In another experiment, the three vaccines were compared in normal mice and in mice that had been rendered tolerant by intravenous injection of M. leprae. The tolerant mice developed no measurable sensitization on vaccination with M. leprae, but they developed partial but distinct sensitization on vaccination with BCG, alone or in combination with M. leprae. The tolerant mice developed little or no protection with any of the vaccines, however..(AU). Descriptors: MYCOBACTERIUM LEPRAE/imunol HANSENIASE/imunol TOLERÂNCIA IMUNOLOGICA VACINACAO RELACAO DOSE-RESPOSTA IMUNOLOGICA VACINAS BACTERIANAS/imunol VACINA BCG/imunol Limits: ESTUDO COMPARATIVO ANIMAL FEMININO CAMUNDONGOS SUPPORT, NON-U.S. GOV'T Electronic Medium: http://www.ilsl.br Location: BR191.1; 01555/s

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Id: 13437 Author: Fine, P. E; Ponnighaus, J. M; Maine, N; Clarkson, J. A; Bliss, L Title: Protective efficacy of BCG against leprosy in Northern Malawi ..- Source: s.l; s.n; August 30, 1986. 4 p. tab. Abstract: The effectiveness of a BCG vaccination programme in protecting against leprosy was assessed by case-control and cohort analyses of data from the Lepra Evaluation Project in Karonga District, Northern Malawi. Results indicate that BCG provides at least 50% protection against leprosy in this population and that protection is independent of age, sex, schooling status, or location within the project area. Agreement between these findings and those from a controlled trial in Uganda indicates that BCG is sufficiently effective against leprosy in East and Central Africa to be considered an important element of leprosy control in that region.(AU). Descriptors: VACINACAO/métodos MALAUI HANSENIASE/epidemiol HANSENIASE/prev ESTUDOS DE AVALIACAO VACINA BCG/imunol Limits: HUMANO MASCULINO FEMININO RECÉM-NASCIDO LACTENTE PRÉ-ESCOLAR CRIANÇA ADULTO SUPPORT, NON-U.S. GOV'T ADOLESCENTE Electronic Medium: http://www.ilsl.br Location: BR191.1; 01786/s

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Id: 13327 Author: Convit, Jacinto; Aranzazu, N; Pinardi, M; Ulrich, M Title: Immunological changes observed in indeterminate and lepromatous leprosy patients and Mitsuda-negative contacts after the inoculation of a mixture of Mycobacterium leprae and BCG ..- Source: s.l; s.n; may 1979. 7 p. tab, graf. Abstract: This investigation was carried out to study the possibility of eliciting favourable immunological changes in small groups of Mitsuda-negative patients...(AU). Descriptors: ANTIGENOS DE BACTERIAS TATUS VACINA BCG ANTIGENO DE MITSUDA/imunol HANSENIASE/imunol HANSENIASE/terap MYCOBACTERIUM LEPRAE/imunol - TRANSFORMACAO LINFOCITICA  FATORES DE TEMPO  VACINACAO Limits: CRIANÇA ADOLESCENTE Electronic Medium: http://www.ilsl.br Location: BR191.1; 01020/s

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Id: 13321 Author: Saha, Kunal; Mittal, Mmdan M; Ray, S. N Title: Consequences of smallpox vaccination in leprosy patients ..- Source: s.l; s.n; sep. 1973. 8 p. tab. Abstract: This study illustrates the consequences of smallpox revaccination in 45 lepromatous, 28 tuberculoid, and 47 normal individuals. Results obtained with leprosy were associated with a relative anergy against the vaccinia virus, the anergy being minimal in the tuberculoid leprosy but marked in the cases with lepromatous leprosy.(AU). Descriptors: HIPERSENSIBILIDADE TARDIA/imunol IMUNIDADE CELULAR IMUNOGLOBULINA A/anal IMUNOGLOBULINA G/anal IMUNOGLOBULINA M/anal INJECOES INTRADERMICAS HANSENIASE/imunol VACINA ANTIVARIOLICA/admin VACINACAO/ef adv VIRUS DA VACÍNIA/imunol - FORMACAO DE ANTICORPOS  CALOR  HEMAGLUTINACAO  IMUNIZACAO SECUNDARIA  INIBICAO (PSICOLOGIA)  MERCAPTOETANOL  COMPLEMENTO/anal  IMUNODIFUSAO Limits: HUMANO ADULTO Electronic Medium: http://www.ilsl.br Location: BR191.1; 01256/s

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Id: 13317 Author: Stanley, Susan J; Howland, C; Stone, Mary M; Sutherland, I Title: BCG vaccination of children against leprosy in Uganda: final results ..- Source: s.l; s.n; oct. 1981. 16 p. tab. Abstract: A total of 19200 children, all contacts or realtives of known leprosy patients, anda all free of visible leprosy lesions, were included in a controlled trial of BCG vaccination against leprosy in Uganda between 1960 and 1964.(AU). Descriptors: VACINA BCG SEGUIMENTOS HANSENIASE/epidemiol HANSENIASE/prev TESTE TUBERCULINICO UGANDA VACINACAO - FATORES DE TEMPO Limits: HUMANO PRÉ-ESCOLAR CRIANÇA ADOLESCENTE Electronic Medium: http://www.ilsl.br Location: BR191.1; 01183/s

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Id: 13309 Author: Bhide, M. B; Dholam, S. B; Chatterjee, B. R Title: Inhibition of foot pad multiplication of M. leprae in mice vaccinated with leproma derived M. leprae precursor coccoid organism and passive transfer of DTH response to normal mice through infusion of splenic cells of such vaccinated mice ..- Source: s.l; s.n; oct. 1981. 8 p. graf. Abstract: Inhibition of foot pad multiplication of M. leprae in mice vaccinated with leproma derived M. leprae precursor coccoid organism and passive transfer of DTH response to normal mice through infusion of splenic cells of such vaccinated mice.(AU). Descriptors: VACINAS BACTERIANAS/imunol HIPERSENSIBILIDADE TARDIA/imunol IMUNIZACAO PASSIVA MYCOBACTERIUM LEPRAE/imunol BACO/transpl VACINACAO Limits: ANIMAL CAMUNDONGOS SUPPORT, NON-U.S. GOV'T Electronic Medium: http://www.ilsl.br Location: BR191.1; 00813/s

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Id: 13166 Author: Aben-Athar, Jaime Title: A lepra como molestia infantil e vaccinante ..- Source: São Paulo; s.n; jul. 1941. 13 p. . Abstract: Ninguém discute mais, atualmente, a natureza contagiosa da lepra. Certas das condições que favorecem este contágio são bem conhecidas e, na prática, provaram a preceito a sua solidez. A cohabitação íntima e demorada parece faciliat este contágio que depende, também, da forma clínica da lepra e do estado em que se encontrem suas lesões. (AU). Descriptors: HANSENIASE/imunol HANSENIASE/prev hanseniase/transmissão hanseniase/etiologia hanseniase/mortalidade hanseniase/prevenção & controle - VACINACAO Limits: CRIANÇA Location: BR191.1; 0925/d.a

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Id: 11290 Author: Nath, Indira Title: A vaccine for leprosy ..- Source: s.l; s.n; 1998. 3 p. ilus, tab. Descriptors: VACINAS BACTERIANAS ENSAIOS CLINICOS REAÇOES CRUZADAS INDIA HANSENIASE MYCOBACTERIUM VACINAÇAO Location: BR191.1; 07229/s

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Id: 11013 Author: Bottasso, Oscar; Merlin, Victor; Cannon, Leslie; Cannon, Helen; Ingledew, Nicholas; Keni, Manjusha; Hartopp, Richard; Stanford, Cynthia; Stanford, John Title: Studies of vaccination of persons in close contact with leprosy patients in Argentina ..- Source: s.l; s.n; 1998. 6 p. tab. Descriptors: HANSENIASE HANSENIASE MYCOBACTERIUM MYCOBACTERIUM BOVIS PREVALENCIA TESTE TUBERCULINICO VACINAÇAO Limits: ADULTO CRIANCA HUMANO Location: BR191.1; 07289/s

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Id: 10949 Author: Lima, M. C. B. S; Pereira, G. M. B; Rumjanek, F. D; Gomes, H. M; Duppre, N; Sampaio, E. P; Alvim, I. M. P; Nery, J. A. C; Sarno, E. N; Pessolani, M. C. V Title: Immunological cytokine correlates of protective immunity and pathogenesis in leprosy ..- Source: s.l; s.n; 2000. 10 p. tab, graf. Descriptors: ADOLESCENCIA VACINA BCG CRIANÇA IMUNIDADE INTERFERON TIPO II INTERLEUCINA-10 HANSENIASE HANSENIASE HANSENIASE LEPROMATOSA HANSENIASE TUBERCULOIDE TRANSFORMAÇAO LINFOCITICA MYCOBACTERIUM LEPRAE TESTES CUTANEOS LINFOCITOS T VACINAÇAO FATOR DE NECROSE TUMORAL/*BI Location: BR191.1; 07459/s

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Id: 10543 Author: Jopling, W. H Title: Vaccination against leprosy ..- Source: s.l; s.n; jan. 1966. 1 p. . Descriptors: HANSENIASE VACINAÇAO Location: BR191.1; 07704/s

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Id: 10537 Author: Corcos, M. G. Title: Vaccination against leprosy ..- Source: s.l; s.n; feb. 1966. 2 p. . Descriptors: HANSENIASE VACINAÇAO Location: BR191.1; 07698/s

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Id: 10118 Author: Bertolli, Jeanne; Pangi, Charles; Frerichs, Ralph; Halloran, M. Elizabeth Title: A case-control study of the effectiveness of BCG vaccine for preventing leprosy in Yangon, Myanmar ..- Source: s.l; s.n; 1997. 9 p. tab. Descriptors: ADOLESCENCIA VACINA BCG ESTUDOS DE CASOS E CONTROLES CRIANÇA ESQUEMA DE MEDICAÇAO HANSENIASE HANSENIASE MIANMA VACINAÇAO Location: BR191.1; 07059/s

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Id: 9928 Author: Collins, C. H; Grange, J. M Title: Mycobacterial disease - old problems, new solutions ..- Source: s.l; s.n; 1996. 2 p. . Descriptors: HANSENIASE HANSENIASE HANSENIASE HANSENIASE MYCOBACTERIUM MYCOBACTERIUM MYCOBACTERIUM TUBERCULOSE TUBERCULOSE TUBERCULOSE TUBERCULOSE TUBERCULOSE AVIARIA TUBERCULOSE AVIARIA TUBERCULOSE AVIARIA TUBERCULOSE BOVINA TUBERCULOSE BOVINA TUBERCULOSE BOVINA VACINAÇAO ANTIBIOTICOS BOVINOS QUIMIOTERAPIA COMBINADA INFECÇOES POR HIV SAUDE PUBLICA Location: BR191.1; 06863/s

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Id: 9813 Author: Nath, Indira Title: Forward to the past ..- Source: s.l; s.n; 1996. 1 p. ilus. Descriptors: HANSENIASE MYCOBACTERIUM BOVIS INFECÇAO LEISHMANIOSE CÉLULAS TH1 CÉLULAS TH2 TUBERCULOSE PULMONAR VACINAÇAO Location: BR191.1; 06735/s

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Id: 9742 Author: Rosa, Heitor; Pedrosa, Suelene; Cardoso, Divina D. P Title: Hepatitis B vaccination in leprosy patients ..- Source: s.l; s.n; 1994. 2 p. tab. Descriptors: HANSENIASE DIMORFA HANSENIASE DIMORFA HANSENIASE LEPROMATOSA HEPATITE B HEPATITE B ANTIGENOS DE SUPERFICIE DA HEPATITE B VACINAS CONTRA HEPATITE B VACINAÇAO Limits: HUMANO Location: BR191.1; 06707/s

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