Database : HANSEN Search on : MICROSCOPIA [Subject descriptor] References found : 39 [refine] Displaying: 1 .. 20   in format [Detailed]

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Id: 18884 Author: Dias, Danilo Moreira. Title: Simplificação da técnica de Perdrau. Source: Rev. bras. Leprol;28(3):149-156, set. 1960. ^bilus. Abstract: O autor desenvolveu uma técnica de impregnação pela prata a partir do método clássico de Perdrau com as seguintes vantagens, entre outras: 1) Economia de tempo, pois executa-se em 25 minutos; 2) Economia de material; 3)É aplicável a esfregaços; 4) Permite o uso de vários fixadores. (AU)^ipt. Descriptors: Hanseníase/imunol Microscopia/hist Microscopia/instrum Microscopia/métodos Equipamentos de Laboratório Electronic Medium: http://hansen.bvs.ilsl.br/textoc/revistas/brasleprol/1960/PDF/v28n3/v28n3a03.pdf / pt Location: BR191.1

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Id: 18512 Author: Bakker, M. I; Hatta, M; Kwenang, A; Van Benthem, B. H. B; Van Beers, S. M; Klatser, P. R; Oskam, L. Title: Prevention of leprosy using rifampicin as chemoprophylaxis. Source: In: Bakker, Mirjam.Epidemiology and prevention of leprosy: a cohort study in Indonesia^ien. s.l, The Netherlands Leprosy Relief, 2005. p.126-139^bilus, ^btab, ^bgraf. Abstract: An intervention study was implemented on five Indinesian island highly endemic for leprosy to determine whether rifampicin can be used as chemoprophylaxis to prevent leprosy. The population was actively screened before the intervention and subsequently once a year for three years. In the control group, no chemoprophylaxis was given. In the contact group, chemoprophylaxis was only given to contacts of leprosy patients and in the blanket group to all aligible persons. The cohort consited of 3,965 persons. The yearly incidence rate in the control group was 39/10,000; the cumulative incidence after three years was significantly lower in the blanket group (P=0.031). No difference was found between the contact and the control groups (P=0.93). Whether this apparent reduced leprosy incidence in the first three years in the blanket group is due to a delayed development of leprosy or a complete clearence of infections needs to be determined (AU)^ien. Descriptors: HANSENIASE/prev MICROSCOPIA/métodos DERMATOLOGIA/estatíst Limits: ESTUDO COMPARATIVO Humanos Location: BR191.1; WC335.300, B179e

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Id: 18235 Author: Roy, A. N Title: Some interesting observations on the cultivation Mycobacterium leprae ..- Source: s.l; s.n; 1966. 2 p. . Abstract: A preliminary report on cultivation of Mycobacterium leprae in artificial media is reported.The work suggests that the modified medium used in this work may help in cultivating Mycobacteria leprae (AU). Descriptors: MYCOBACTERIUM LEPRAE/cresc MYCOBACTERIUM LEPRAE/isol MEIOS DE CULTURA/quim - MICROSCOPIA/util Limits: IN VITRO Location: BR191.1; 09280/s

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Id: 17720 Author: Wen, Dong Li Title: Microscopic surgical techniques in leprosy ..- Source: Shanghai; STD; 2001. 87 p. ilus, tab. Descriptors: HANSENIASE/diag HANSENIASE/reabil HANSENIASE/cirurg MICROSCOPIA/instrum MICROSCOPIA/métodos Limits: RELATO DE CASO ESTUDO COMPARATIVO HUMANO Location: Br191.1; WC335.603, W48m

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Id: 15441 Author: Antunes, Altino Title: Como verificar os casos de lepra? ..- Source: São Paulo; s.n; jan. 1940. 5 p. . Abstract: Na ultima reunião da Sociedade de Medicina, além do importante trabalho sobre o Bactereophago de D'Herelle, do dr. Lemos Monteiro e sobre o qual esse illustre medico nos concedeu interessante entrevista, foi tambem apresentada documentada e opportuna comunicação do Dr. Altino Antunes, competente e conceituado bacteriologista, que se occupou da pesquisa do bacillo de Hansen nas manchas cutaneas.(AU). Descriptors: HANSENIASE/diag HANSENIASE/microbiol MYCOBACTERIUM LEPRAE - MICROSCOPIA/util Location: BR191.1; 0925/d.a

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Id: 14461 Author: Barros, J. Mendonça. Title: Os diferentes métodos de iluminação aplicados á biomicroscopia do olho leproso. Source: Rev. bras. Leprol;7(n.esp):155-158, 1939. . Descriptors: HANSENIASE HANSENIASE/clas HANSENIASE/diag HANSENIASE/microbiol MICROSCOPIA/clas MICROSCOPIA/métodos Electronic Medium: http://hansen.bvs.ilsl.br/textoc/revistas/Edicao%20Especial/1939/PDF/Ed.esp.a11.pdf / pt Location: BR191.1

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Id: 13790 Author: Hagge, Deanna A; Robinson, Sandra Oby; Scollard, David; McCormick, Gregory; Williams, Diana L Title: A new model for studyng the effects of Mycobacterium leprae on Schwann cell and neuron interactions ..- Source: s.l; s.n; 2002. 14 p. ilus, tab. Abstract: Millions of patients with leprosy suffer from nerve damage resulting in disabilities as a consequence of Mycobacterium leprae infection. However, mechanisms of nerve damage have not been elucidated because of the lack of a model that maintains M. leprae viability and mimics disease conditions. A model was developed using viable M. leprae, rat Schwann cells, and Schwann cell-neuron cocultures incubated at 33 degrees C. M. leprae retained 56 per cente viability in Schwann cells for 3 weeks after infection at 33 degrees C, compared with 3.6 per cente viability at 37 degrees C. Infected Schwann cells had altered morphology and expression of genes encoding cellular adhesion molecules at 33 degrees C but were capable of interacting with and myelinating neurons. Cocultures, infected after myelination occurred, showed no morphological changes in myelin architecture after 1 month of incubation at 33 degrees C, and M. leprae retained 53 per cente viability. This article describes a new model for studying the effects of M. leprae on Schwann cells. (AU). Descriptors: CAMUNDONGOS NUS HANSENIASE/microbiol HANSENIASE/patol MODELOS NEUROLOGICOS MICROSCOPIA ELETRÔNICA DE VARREDURA CELULAS CULTIVADAS NEURÔNIOS/microbiol NEURÔNIOS/patol NEURÔNIOS/fisiol COMUNICACAO CELULAR/fisiol MYCOBACTERIUM LEPRAE/cresc MYCOBACTERIUM LEPRAE/fisiol CELULAS DE SCHWANN/microbiol CELULAS DE SCHWANN/patol CELULAS DE SCHWANN/fisiol CELULAS DE SCHWANN/ultraest Limits: HUMANO ANIMAL CAMUNDONGOS RATOS SUPPORT, NON-U.S. GOV'T Electronic Medium: http://www.ilsl.br Location: BR191.1; 09030/s

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Id: 13607 Author: Job, Charles K Title: Mycobacterium leprae in nerve lesions in lepromatous leprosy ..- Source: s.l; s.n; mar. 1970. 13 p. ilus. Abstract: The ultrastructure of radial cutaneous nerve biopsies from five untreated patients with lepromatous leprosy was studied. Mycobacterium leprae prenet in large numbers frequently in Schwann cells, macrophages, and endothelial cells, and occasionally in perineural cells. Proliferation of the bacilli inside these cells resulted in their foamy degeneration. It is pointed out that the Schawann cells is the target cell in the leprous infection of the nerves and that the destructive lesions of the nerves produced in lepromatous leprosy are esentially the result of Schwann-cell degeneration. Mycobacterium leprae was demonstrated in the lumen of the capillaries as well, and it is suggested that the infection may spread in the body even into the nerves through the blood-stream.(AU). Descriptors: HANSENIASE/microbiol HANSENIASE/patol MICROSCOPIA ELETRÔNICA MYCOBACTERIUM LEPRAE/isol CELULAS DE SCHWANN Limits: HUMANO Electronic Medium: http://www.ilsl.br Location: BR191.1; 00513/s

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Id: 13578 Author: Kramarsky, Bernard; Edmondson, Hugh A; Peters, Robert L; Reynolds, Telfer B Title: Lepromatous leprosy in reaction ..- Source: s.l; s.n; May 1968. 16 p. ilus. Abstract: Biopsies of the skin and liver were obtained from a patient with Lucio's type of leprosy and from one with erythema nodosum leprosum. Vasculitis, a dense inflammatory exudate, and necrosis of the skin characterized the Lucio type of leprosy; in erythema nosodum leprosum the vasculitis was not so severe and necrosis did not occur. Large numbers of organisms in the endothelial cells of the vessels in the skin could have given rise to bacteremia and development of the disease in the liver. The liver in the patient with Lucio's phrnomenon contained tuberculoid lesions, whereas necrosis of sinusoidal walls and many Virchow's cells were noted in the other patient. Lperosy bacilli in Kupffer cells were easily demonstrated with electron microscopy. The presence of the bacteria within membrane-bound phagocytic vacuoles and the fusion of lysosomes with the vacuoles were seen.(AU). Descriptors: GRANULOMA/etiol GRANULOMA/patol HANSENIASE/compl HANSENIASE/patol NECROSE PELE/microbiol PELE/patol MYCOBACTERIUM LEPRAE/citol MYCOBACTERIUM LEPRAE/isol - MICROSCOPIA ELETRÔNICA  MITOCÔNDRIA  NEUTROFILOS  FAGOCITOSE Limits: HUMANO MASCULINO FEMININO ADULTO Electronic Medium: http://www.ilsl.br Location: BR191.1; 00765/s

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Id: 13530 Author: Hagge, Deanna; Robinson, Sandra Oby; Scollard, David; McCormick, Gregory; Williams, Diana L Title: A new model for studying the effects of Mycobacterium leprae on Schwann cell and neuron interactions ..- Source: s.l; s.n; 2002. 4 p. tab. Abstract: Millions of patients with leprosy suffer from nerve damage resulting in disabilities as a consequence of Mycobacterium leprae infection. However, mechanisms of nerve damage have not been elucidated because of the lack of a model that maintains M. leprae viability and mimics disease conditions. A model was developed using viable M. leprae, rat Schwann cells, and Schwann cell-neuron cocultures incubated at 33 degrees C. M. leprae retained 56% viability in Schwann cells for 3 weeks after infection at 33 degrees C, compared with 3.6% viability at 37 degrees C. Infected Schwann cells had altered morphology and expression of genes encoding cellular adhesion molecules at 33 degrees C but were capable of interacting with and myelinating neurons. Cocultures, infected after myelination occurred, showed no morphological changes in myelin architecture after 1 month of incubation at 33 degrees C, and M. leprae retained 53% viability. This article describes a new model for studying the effects of M. leprae on Schwann cells. (AU). Descriptors: COMUNICACAO CELULAR/fisiol CELULAS CULTIVADAS HANSENIASE/microbiol HANSENIASE/patol CAMUNDONGOS NUS MODELOS NEUROLOGICOS NEURÔNIOS/microbiol NEURÔNIOS/patol NEURÔNIOS/fisiol CELULAS DE SCHWANN/microbiol CELULAS DE SCHWANN/patol CELULAS DE SCHWANN/fisiol CELULAS DE SCHWANN/ultraest MICROSCOPIA ELETRÔNICA DE VARREDURA MYCOBACTERIUM LEPRAE/cresc MYCOBACTERIUM LEPRAE/fisiol Limits: ANIMAL HUMANO CAMUNDONGOS RATOS SUPPORT, NON-U.S. GOV'T Location: BR191.1; 08982/s

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Id: 13459 Author: Hayes, Thomas G Title: Structure of the ellipsoid sheath in the spleen of the armadillo (Dasypus novemcinctus). A light and electron microscopic study ..- Source: s.l; s.n; oct. 1970. 17 p. ilus. Abstract: The spleen of the armadillo is invested by a capsule composed predominantly of smooth muscle. Inward extensions from the capsule contribute to an extensive system of trabeculae of the non-vascular type. The white pulp presents series of venous sinsuses. The capillary segment of the penicillar artery is invested by an ellipsoid sheath. The spleen of the armadillo may be included in the class of mammalian spleens characterized as sinusal in nature and possessing ellipsoid sheaths. Electron micrographs of thin sections of the sheathed capillaries demonstrate a high-type of endothelium. A characteristic feature of this endothelium is the presence of a distinct intracytoplasmic fibrous component. The reticular cells comprising the sheath proper exhibit various sized vacuoles and inclusion bodies suggestive of their potentially phagocytic nature. In both light and electron microscopy, venous sinuses lie in close proximity to the paripheral cells of the ellipsoid sheaths. Within the wall of the venous sinuses, patent openings are apparent between the lining cells. If such an arrangement exists in the functional state of the organ, it could provide for an additional means of exposure of both plasma and cellular elements to the adjacent phagocytic cells of the sheath proper.(AU). Descriptors: COLORACAO E ROTULAGEM MICROSCOPIA ELETRÔNICA TECNICAS HISTOLOGICAS GRÂNULOS CITOPLASMATICOS CAPILARES/citol RETICULOCITOS/citol XENARTROS/anat BACO/anat BACO/irrig BACO/citol Limits: ANIMAL Electronic Medium: http://www.ilsl.br Location: BR191.1; 01435/s

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Id: 13434 Author: Saha, Kunal; Chakraborty, Asit K; Prakash, Nam Title: A quick method of demonstrating bacillaemia in patients with lepromatous leprosy and ultrastructural studies of the circulating acid-fast bacilli ..- Source: s.l; s.n; 1983. 5 p. ilus, tab. Abstract: While studying circulating immune complexes (CIC) in the sera of lepromatous patients by the polyethylene glycol (PEG) precipitation technique, we found (by light microscopy) abundant acid-fast bacilli (AFB), morphologically similar to those seen in slit skin smear preparations from these patients, precipitated with the PEG precipitated materials. Both solid and non-solid AFB could be readily identified. Ultrastructures of these AFB in the PEG aggregates showed some similarity with those detected in the PEG precipitates prepared from armadillo-derived lepromin under identical conditions. The most striking difference between the AFB in the test sera and that in the armadillo-derived lepromin was the absence of any transverse band in the former. This suggested that the AFB in the patients' circulation were not in division stage. Furthermore, electron-dense material were deposited on the AFB co-precipitated from the patients' sera, which were not found on the AFB co-precipitated from the armadillo-derived lepromin.(AU). Descriptors: TATUS TECNICAS BACTERIOLOGICAS SANGUE/microbiol ANTIGENO DE MITSUDA HANSENIASE/microbiol MICROSCOPIA ELETRÔNICA SEPTICEMIA/microbiol MYCOBACTERIUM LEPRAE/isol MYCOBACTERIUM LEPRAE/ultraest - PRECIPITACAO  POLIETILENOGLICOIS Limits: HUMANO ANIMAL ADULTO MEIA-IDADE IDOSO Electronic Medium: http://www.ilsl.br Location: BR191.1; 01767/s

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Id: 13366 Author: Bullock, W. E; Callerame, M. L; Panner, B. J Title: Immunohistologic alteration of skin and ultrastructural changes of glomerular basement membranes in leprosy ..- Source: s.l; s.n; jan. 1974. 6 p. ilus. Abstract: Immunofluorescent banding of the dermal-epidermal junction of skin was demonstrated in 3 of 7 patients with lepromatous leprosy by direct immunofluorescence microscopy. The banding was caused specifically by deposition of IgM. Within the glomeruli of one patient, dense, amorphous deposits in subendothelial and intramembranous position were also demonstrated by electron microscopy. These preliminary findings suggest that lepromatous leprosy may be associated with immunologic disurbances of both skin and glomerular basement membranes.(AU). Descriptors: MEMBRANA BASAL/imunol MEMBRANA BASAL/patol GLOMERULONEFRITE/patol HAPLORHINI GLOMERULOS RENAIS/patol HANSENIASE/compl HANSENIASE/imunol HANSENIASE/patol IMUNOGLOBULINA M MICROSCOPIA DE FLUORESCÊNCIA Limits: HUMANO ANIMAL MASCULINO FEMININO ADULTO Electronic Medium: http://www.ilsl.br Location: BR191.1; 01795/s

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Id: 13343 Author: Anthony, J; Vaidya, M. C; Dasgupta, A Title: Ultrastructure of nerve in erythema nodosum leprosum (ENL) ..- Source: s.l; s.n; 1979. 4 p. ilus. Abstract: Gross changes of myelinated fibres and Schwann cells at different degenerative stages were present in all five ENL nerve lesions. Besides these changes, infiltrating cells mainly macrophages, deposition of excessive collagen and perineurial vessel damage were also observed.(AU). Descriptors: CELULAS DE SCHWANN/ultraest ERITEMA NODOSO/patol HANSENIASE/patol DEGENERACAO NEURAL FIBRAS NERVOSAS MIELINIZADAS/ultraest - SISTEMA NERVOSO/ultraest  COLAGENO  ORELHA/inerv  MICROSCOPIA ELETRÔNICA  CELULAS SANGUINEAS Limits: HUMANO Electronic Medium: http://www.ilsl.br Location: BR191.1; 01060/s

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Id: 13208 Author: Job, C. K Title: Mechanism of nerve destruction in tuberculoid-borderline leprosy ..- Source: s.l; s.n; sep. 1973. 14 p. ilus. Abstract: The ultrastructural changes in radial cutaneous nerve biopsies from 3 tuberculoid and 14 tuberculoid-borderline patients were studied. In tuberculoid leprosy the nerve parenchyma was almost entirely replaced by tuberculoid granuloma. In nerves from borderline-tuberculoid leprosy many axons showed segmental demyelination and Wallerian degeneration. The nerve tissue was gradually replaced by proliferating collagen fibrils and inflammatory granulomata. M. leprae were rare and when present they were found in phagolysosomes of Schwann cells and macrophages. Schwann cells were surrounded and occasionally infiltrated by lymphocytes and macrophages. It was suggested that "sensitized Schwann cells" were the target of a hypersensivity reaction resulting in their degeneration or death which in turn produced segmental demyelination or Wallerian degeneration.(AU). Descriptors: HANSENIASE/imunol HANSENIASE/microbiol HANSENIASE/patol DOENCAS DESMIELINIZANTES ANTIGENOS DE BACTERIAS MICROSCOPIA ELETRÔNICA MYCOBACTERIUM LEPRAE/isol NERVOS PERIFERICOS/patol CELULAS DE SCHWANN Limits: HUMANO Electronic Medium: http://www.ilsl.br Location: BR191.1; 02021/s

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Id: 11316 Author: Shimoji, Yoshihiro; Ng, Vincent; Matsumura, Kiichiro; Fischetti, Vincent A; Rambukkana, Anura Title: A 21-kDa surface protein of mycobacterium leprae binds peripheral nerve laminin-2 and mediates Schwann cell invasion ..- Source: s.l; s.n; 1999. 6 p. tab, graf. Descriptors: SEQUENCIA DE AMINOACIDOS ADESINAS BACTERIANAS ADESINAS BACTERIANAS SEQUENCIA DE BASES ELETROFORESE EM GEL DE POLIACRILAMIDA LAMININA HANSENIASE CAMUNDONGOS CAMUNDONGOS ENDOGAMICOS BALB C MICROSCOPIA IMUNOELETRONICA DADOS DE SEQUENCIA MOLECULAR PESO MOLECULAR MYCOBACTERIUM LEPRAE SISTEMA NERVOSO PERIFÉRICO SISTEMA NERVOSO PERIFÉRICO CÉLULAS DE SCHWANN PROPRIEDADES DE SUPERFICIE CELULAS CULTIVADAS Limits: ANIMAL Location: BR191.1; 07255/s

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Id: 11064 Author: Scollard, David M Title: Association of mycobacterium leprae with human endothelial cells in vitro ..- Source: s.l; s.n; may 2000. 7 p. ilus, graf. Descriptors: HANSENIASE MYCOBACTERIUM LEPRAE ENDOTÉLIO VASCULAR ENDOTÉLIO VASCULAR ENDOTÉLIO VASCULAR MICROSCOPIA ELETRONICA Location: BR191.1; 07444/s

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Id: 10975 Author: Maslov, A. K; Luzhnova, S. A Title: Effects of peroxidase therapy on functional state of the liver and phagocytes and blood cell counts in mice with experimental leprosy ..- Source: s.l; s.n; 2000. 5 p. ilus, tab, graf. Descriptors: HANSENIASE HANSENIASE FIGADO FIGADO CONTAGEM DE CÉLULAS SANGUINEAS PEROXIDASE DO RABANO SILVESTRE MICROSCOPIA ELETRONICA PEROXIDASE FAGOCITOS FAGOCITOS CAMUNDONGOS ENDOGAMICOS CBA Limits: ANIMAL CAMUNDONGOS Location: BR191.1; 07330/s

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Id: 10961 Author: Kajihara, Hiroki; paturusi, Idrus A; Saleh, Ruksal M; Rasyad, Chairuddin; Ikuta, Yoshikazu Title: Light and electron microscopic study of peripheral nerve damage in patients with lepromatous leprosy (LL) and borderline lepromatous leprosy (BL) ..- Source: s.l; s.n; 2000. 10 p. ilus, tab. Descriptors: ADOLESCENCIA CRIANÇA HANSENIASE DIMORFA HANSENIASE DIMORFA HANSENIASE LEPROMATOSA HANSENIASE LEPROMATOSA MICROSCOPIA ELETRONICA NERVO RADIAL NERVO RADIAL NERVO RADIAL Location: BR191.1; 07432/s

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Id: 10957 Author: Hong, Seung-Mo; Ha, Hongil; Suh, Jae-Hee; Kim, Kwang-KukKhang, Shin Kwang; Ro, Jae Y; Park, Sung-Hye Title: Clinicopathologic analysis of 124 biopsy-proven peripheral nerve diseases ..- Source: s.l; s.n; 2000. 6 p. ilus, tab. Descriptors: BIOPSIA DOENÇA DE CHARCOT-MARIE DOENÇAS DESMIELINIZANTES DOENÇA DE FABRY NEUROPATIAS MOTORAS E SENSORIAIS HEREDITARIAS CORÉIA (GEOGRAFICO) HANSENIASE MICROSCOPIA ELETRONICA FIBRAS NERVOSAS MIELINIZADAS NERVOS PERIFÉRICOS NERVOS PERIFÉRICOS DOENÇAS DO SISTEMA NERVOSO PERIFÉRICO DOENÇAS DO SISTEMA NERVOSO PERIFÉRICO NERVO SURAL NERVO SURAL Location: BR191.1; 07436/s

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