Database : HANSEN Search on : HANSENIASE/ENZIMOL [Subject descriptor] References found : 19 [refine] Displaying: 1 .. 19   in format [Detailed]

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Id: 18502 Author: Portugal, Hildebrando Title: Diagnóstico da lepra pelo laboratório^ipt Diagnosis of leprosy by the laboratory- Source: São Paulo; s.n; 1940. 48 p. . Abstract: EXAME DIRECTO - 1.-PESQUIZA na mucosa nasal - Esse processo, introduzido na pratica por JEANSELME em 1897, ‚ um dos meios usuais para o diagnóstico. Em virtude da frequencia com que o germen ‚ encontrado na mucosa nasal julgous-e que a lesão primaria, o cancro leproso, ahi se localizasse. (AU)^ipt. Descriptors: HANSENIASE/sangue HANSENIASE/enzimol HANSENIASE/imunol HANSENIASE/metab HANSENIASE/enf HANSENIASE/fisiopatol HANSENIASE/virol Limits: Humanos RELATO DE CASO Location: BR191.1; 01072/d.a

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Id: 18109 Author: Silva, Nilson Carvalho da; Zeo, Arnaldo; Azulay, Rubem David; R Netto, Americo Vieira Title: Possibilidades do G 30 320 no tratamento da hanseniase e da reação leprotica Possibilities of G 30 320 me the treatment of leprosy and reaction leprosy- Source: Rio de Janeiro; s.n; s.d. 8 p. ilus. Abstract: Os AA selecionaram doentes de lepra internados no Hospital Colonia Curupaiti e Hopsital Frei Antonio do Estado da Guanabara, Brasil, para experimentação da atividade antilepra do G 30 320. Todos oos pacinetes são da forma lepromatosa graus L1, L2,L3 e dimorfos, classificados nos seguinte Grupos:I - Doentes novos, virgens de tratamentoII - Doentes sulfono-resistentes com lepra progressiva avançadaIII - Doentes sujeitos a reação tipo ENL, talidomido dependentes. Desencadeia-se a reação sempre que se instituti tratamento sulfonico sem a respectiva e continua cobertura com talidomidaIV - Doentes talidomida insensiveis sujeitos a reação de ENI incontrolavel pelos metodos tradicionais inclusive talidomidaA experiencia tem por objetivo a verificação da utilidade do novo produito G 30 320 no controle do desenvvolvimento da Hanseniase e da reação leprotica. O esquema basico de administração tem sido 2 capisulas por dia durante 7 dias reduzindo-se então para l capsula diaria. Cada capsula contem l00 mg. de um derivado anilino aposafraninado G 30 320...(AU). Descriptors: HANSENIASE/enzimol HANSENIASE/epidemiol HANSENIASE/reabil HANSENIASE/terap MICOBACTERIAS ATIPICAS/quim MICOBACTERIAS ATIPICAS/genet MICOBACTERIAS ATIPICAS/imunol MICOBACTERIAS ATIPICAS/isol MICOBACTERIAS ATIPICAS/metab Limits: ESTUDO COMPARATIVO HUMANO Location: BR191.1; 01077/s

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Id: 13512 Author: Blennerhassett, John B; Papadimitriou, J. M Title: Muramidase content of cells in human granulomatous reactions ..- Source: s.l; s.n; jan. 1981. 9 p. ilus. Abstract: The muramidase content of reactive cells in the lesions of human foreign body reactions, lepromatous and tuberculoid leprosy, sarcoidosis, tuberculosis, and granulomatous hepatitis, was assessed using specific anti-human muramidase antiserum and a peroxidase-anti-peroxidase marker system. Epithelioid and giant cells in sarcoidosis, tuberculosis, granulomatous hepatitis, and tuberculoid leprosy all showed the presence of muramidase in their cytoplasm. The muramidase content of macrophages in foreign body reactions and lepromatous leprosy varied and most multinucleate cells in these lesions gave a negative reaction. Possibly varying rates of muramidase secretion may account for these differences.(AU). Descriptors: LINFONODOS/enzimol MURAMIDASE/metab HANSENIASE/enzimol PULMAO/enzimol SARCOIDOSE/enzimol TUBERCULOSE/enzimol HEPATITE/enzimol REACAO A CORPO ESTRANHO/enzimol CITOPLASMA/enzimol Limits: HUMANO Electronic Medium: http://www.ilsl.br Location: BR191.1; 00459/s

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Id: 13489 Author: Gómez-Estrada, Hector; Morales-Ortiz, Roberto; González-Mendoza, Amado; Barba-Rubio, Jose; Ceja-Mendoza, Sagrario Title: Peroxidase deficiency in histiocytes of patients with nodular lepromatous leprosy ..- Source: s.l; s.n; Apr.-Jun. 1983. 11 p. ilus, tab. Abstract: The purpose of this study was to investigate the presence of peroxidase (PO) in the histiocytes which are found in the lepromatous lesions of patients with nodular lepromatous leprosy (NLL). We studied dermoepidermal biopsy specimens from lepromstous lesions and blood smears of 10 patients with NLL, eight males and twoo females 28 to 63 years age (average 45 + or - 6.2), of which nine coursed with the stable form of the disease and one was in lepromatous reaction. Six had received treatment with diaminodiphenylsulphone for more than six months, and the other four, none. As controls we studied the blood smears of 10 healthy controls and 10 rat liver sections. PO was investigated in histiocytes, Kupffer cells and polymorphonuclears by dichlorhydrate oxydation, according to the technique of Kaplow. By means of Fite-Faraco´s stain, all ten cases proved to have abundant phagocytized M. leprae. PO was not found in histiocytes of lepromatous lesions in nine cases of stable NLL in lepromatous reaction. PO was present in Kupffer cells, in polymorphonuclears of patients with NLL and in controls. No difference was found either in the PO or M. leprae contents between treated and untreated patients. The PO deficiency in histiocytes of patients with NLL may be related to an incapacity of these cells to destroy M. leprae.(AU). Descriptors: PELE/enzimol PELE/patol FAGOCITOSE PEROXIDASES/defic HANSENIASE/enzimol HANSENIASE/patol HISTIOCITOS/enzimol Limits: HUMANO ANIMAL MASCULINO FEMININO ADULTO MEIA-IDADE IDOSO RATOS Electronic Medium: http://www.ilsl.br Location: BR191.1; 01309/s

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Id: 13488 Author: Yamashita, Kiyoaki; Iwamoto, Toshiyuki; Iijima, Soichi Title: Immunohistochemical observation of lysozyme in macrophages in leprosy ..- Source: s.l; s.n; sep. 1978. 7 p. ilus, tab. Abstract: Lysozyme activities of skin granulomas of 24 patients in leprosy were studied. Lepra cells of all 15 lepromatous leprosy showed strong lysozyme activity in cytoplasma. In the specimens stained with lysozyme and Ziehl-Neelsen's carbolfuchsin double stain conspicuous lysozyme activity around M. leprae were observed. One borderline case was negative. Lysozyme of epithelioid cells and giant cells of 10 tuberculoid types were completely negative. These results suggest that lysozyme plays only a small role in the disposal of M. leprae in macrophages and other mechanisms than bacteriolytic function of lysozyme are responsible for the defence against these bacilli.(AU). Descriptors: HANSENIASE/enzimol MACROFAGOS/enzimol MACROFAGOS/microbiol MURAMIDASE/metab PELE/enzimol MYCOBACTERIUM LEPRAE/citol Limits: HUMANO Electronic Medium: http://www.ilsl.br Location: BR191.1; 01308/s

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Id: 13487 Author: McKeever, Paul E; Walsh, Gerald P; Storrs, Eleanor E; Balentine, J. Douglas Title: Electron microscopy of peroxidase and acid phosphatase in leprous and uninfected armadillo macrophages: a macrophage subpopulation contains peroxisomes and lacks bacilli ..- Source: s.l; s.n; sep. 1978. 11 p. ilus. Abstract: Lepromatous tissue from armadillos inoculated 24--36 months earlier with Mycobacterium leprae was obtained for electron microscopic studies. Cytochemically stained lepromas revealed a subpopulation of macrophages containing peroxisomes. These peroxidase reactive macrophages were not infected with bacilli. Acid phosphatase was present in macrophages and many of these were infected with bacilli and contained vacuoles and lipid globules. Within the membrane-bound vacuoles, acid phosphatase surrounded bacilli. However, the reaction product ended abruptly at a 15--40 millimicron thick zone of low electron density surrounding intact bacilli. Acid phosphatase was more intensely reactive and localized less precisely in heavily infected and vacuolated macrophages than in lightly and non-infected cells. The effectiveness of this bacillary barrier and the numerous infected macrophages with substantial acid phosphatase argue against the ability of acid phosphatase to protect host cells from leprosy bacilli. Evidence suggests a protective action of peroxidase or the rapid turnover of macrophages within lepromas. Granular and membranous debris were commonly seen within vacuoles of infected macrophages. A portion of the debris was ultrastructurally similar to bacillary matrix and was nonreactive for peroxidase and acid phosphatase. Following homogenization and centrifugation, similar materials banded with bacilli above 60% sucrose. Another portion of the debris was ultrastructurally similar to host lysosomal matrix and was reactive for acid phosphatase. Results support the concept of dual host and parasitic origins of the debris found in phagolysosomes of infected macrophages. Transparent, oval Epon defects remained eccentric to the majority of intact bacilli in centrifuged fractions. Apparently, an intrinsic property of leprosy produced these Epon defects.(AU). Descriptors: PEROXIDASES/metab HISTOCITOQUIMICA MODELOS ANIMAIS DE DOENCAS MYCOBACTERIUM LEPRAE/isol MACROFAGOS/enzimol MACROFAGOS/microbiol HANSENIASE/enzimol HANSENIASE/microbiol Limits: ESTUDO COMPARATIVO ANIMAL SUPPORT, U.S. GOV'T, P.H.S. FOSFATASE ACIDA/*ME TATUS Electronic Medium: http://www.ilsl.br Location: BR191.1; 1307/s

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Id: 13264 Author: Beiguelman, Bernardo; Pinto, W; Dall'aglio, F. F; Silva, E. da; Vozza, J. A Title: G-6PD deficiencyamong lepers and healthy people in Brazil ..- Source: s.l; s.n; 1968. 4 p. . Abstract: The frequency of G-6PD deficiency was investigated among 323 white and 83 negro lepromatous patients and 234 normal. White people by means of Motulsky and Campbell-Kraut´s decolorization technique. No significant difference between healtly and lepromatous individuals in the frequency of this trait was apparent.(AU). Descriptors: DEFICIÊNCIA DE GLUCOFOSFATO DESIDROGENASE/epidemiol BRASIL RACA CAUCASOIDE FREQUÊNCIA DO GENE HANSENIASE/enzimol - RACA NEGRA Limits: HUMANO MASCULINO Electronic Medium: http://www.ilsl.br Location: BR191.1; 0715/s

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Id: 12309 Author: Kang, Tae-Jin; You, Ji-Chang; Chae, Gue-Tae Title: Identification of catalase-like activity from mucobacterium leprae and the relationship between catalase and isonicotinic acid hydrazide (INH) ..- Source: s.l; s.n; 2001. 7 p. ilus, tab, graf. Descriptors: SULFATO DE AMONIO ANTITUBERCULOSOS SEQUENCIA DE BASES BENZIDINAS CATALASE CATALASE PRIMERS DO DNA DNA COMPLEMENTAR ELETROFORESE EM GEL DE AGAR PEROXIDO DE HIDROGENIO ISONIAZIDA HANSENIASE HANSENIASE MACROFAGOS PERITONEAIS CAMUNDONGOS CAMUNDONGOS ENDOGAMICOS BALB C MYCOBACTERIUM LEPRAE MYCOBACTERIUM LEPRAE - PEROXIDASE  PEROXIDASES  PEROXIDASES  REAÇAO EM CADEIA POR POLIMERASE  DNA POLIMERASE DIRIGIDO POR RNA  CONTAGEM DE CINTILAÇAO  HOMOLOGIA DE SEQUENCIA DO ACIDO NUCLÉICO  ESPECTROFOTOMETRIA Location: BR191.1; 08638/s

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Id: 11495 Author: Kang, Tae-Jin; You, Ji-Chang; Chae, Gue-Tae Title: Identification of catalase like activity from mycobacterium leprae and the relationship between catalase and isonicotinic acid hydrazide (INH) ..- Source: s.l; s.n; 2001. 7 p. ilus, tab, graf. Descriptors: HANSENIASE HANSENIASE ANTITUBERCULOSOS BENZIDINAS CATALASE CATALASE MYCOBACTERIUM LEPRAE MYCOBACTERIUM LEPRAE PRIMERS DO DNA DNA COMPLEMENTAR ELETROFORESE EM GEL DE AGAR PEROXIDO DE HIDROGENIO ISONIAZIDA MACROFAGOS PERITONEAIS PEROXIDASE PEROXIDASE REAÇAO EM CADEIA POR POLIMERASE CONTAGEM DE CINTILAÇAO HOMOLOGIA DE SEQUENCIA DO ACIDO NUCLÉICO Location: BR191.1; 08385/s

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Id: 11294 Author: Endoh, Masumi; Ueki, Akira; Takahashi, Keikichi; Yamanaka, Hideki; Izumi, Shinzo; Tabira, Takeshi Title: Alpha-1-antichymotrypsin is not associated with the increased frequency of apolipoprotein-E- epsilon-4 allele in elderly non-demented leprosy patients ..- Source: s.l; s.n; 1998. 3 p. tab. Descriptors: ALELOS APOLIPOPROTEINAS E APOLIPOPROTEINAS E GENOTIPO HANSENIASE HANSENIASE HANSENIASE ALFA 1-ANTIQUIMOTRIPSINA ALFA 1-ANTIQUIMOTRIPSINA Location: BR191.1; 07233/s

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Id: 9753 Author: Deshpande, R. G; Khan, M. B; Bhat, D. A; Navalkar, R. G Title: Superoxide dismutase activity of Mycobacterium tuberculosis isolated from tuberculosis patients and the immunoreactivity of superoxide dismutase from M. tuberculosis H37Rv ..- Source: s.l; s.n; 1993. 7 p. ilus, tab. Descriptors: HANSENIASE MYCOBACTERIUM TUBERCULOSIS MYCOBACTERIUM TUBERCULOSIS ANTICORPOS ANTIBACTÉRIAS WESTERN BLOTTING ELETROFORESE EM GEL DE POLIACRILAMIDA ELISA HIPERSENSIBILIDADE TARDIA SUPEROXIDO DISMUTASE SUPEROXIDO DISMUTASE TUBERCULOSE PULMONAR Limits: HUMANO Location: BR191.1; 06696/s

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Id: 9489 Author: Kumar, B; Jaswal, S; Vaishnavi, C; Thakur, M; Kaur, S; Ganguly, N. K Title: Release of acid hydrolases in spectrum of human leprosy ..- Source: s.l; s.n; 1992. 7 p. tab. Descriptors: ACETILGLUCOSAMINIDASE GLUCURONIDASE HANSENIASE HANSENIASE HANSENIASE MONOCITOS ZIMOSAN/PD Location: BR191.1; 06345/s

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Id: 9450 Author: Dhople, Arvind M Title: Changes in hydrolytic enzyme activities in armadillos infected with Mycobacterium leprae ..- Source: s.l; s.n; 1991. 10 p. tab. Descriptors: TATUS MODELOS ANIMAIS DE DOENÇAS VIRILHA HIDROLASES HANSENIASE FIGADO FIGADO GANGLIOS LINFATICOS GANGLIOS LINFATICOS MYCOBACTERIUM LEPRAE PESO DOS ORGAOS BAÇO BAÇO Location: BR191.1; 06310/s

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Id: 9420 Author: Vaishnavi, C; Dhawan, V; Ganguly, N. K; Sethi, A; Kumar, B Title: Hydrolytic enzymes leprosy sera ..- Source: s.l; s.n; 1992. 4 p. . Descriptors: ACETILGLUCOSAMINIDASE FOSFATASE ALCALINA GLUCURONIDASE HANSENIASE HANSENIASE Location: BR191.1; 06382/s

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Id: 9409 Author: Sehgal, V. N; Bhattacharya, S. N; Shah, Y; Rao, Y. N; Gupta, C. K Title: Lymphocyte adenosine deaminase activity (L-ADA) in leprosy, during and after treatment of reactions ..- Source: s.l; s.n; 1992. 4 p. tab. Descriptors: ADENOSINA DESAMINASE ADOLESCENCIA HANSENIASE HANSENIASE LINFOCITOS Location: BR191.1; 06393/s

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Id: 9338 Author: Near, Karen A; Lefford, Maurice J Title: Use of serum antibody and lysozyme levels for diagnosis of leprosy and tuberculosis ..- Source: s.l; s.n; 1992. 6 p. ilus, tab, graf. Descriptors: ANTICORPOS ANTIBACTÉRIAS ANTIGENOS DE BACTÉRIAS GLICOLIPIDIOS INFECÇOES POR HIV IMUNOENSAIO HANSENIASE HANSENIASE HANSENIASE LIPOPOLISSACARIDIOS MURAMIDASE TUBERCULOSE TUBERCULOSE TUBERCULOSE Location: BR191.1; 06464/s

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Id: 7087 Author: Pacin, Ana; Fliess, Enrique L. Title: Estudios enzimaticos en pacientes hansenianos. I. Actividade de las transminasas glutamico piruvica y glutamico oxacetica / Enzymatic studies in leprosy patients. Activity of transaminasas glutámico pirúvica and oxalacética glutámico Source: Hansen. Int;3(2):151-159, 1978. tab, graf. Abstract: Se estúdio la actividad enzimática de Got y GPT em 130 pacientes hansenianos divididos em cuatro grupos: hanseniasis virchowiana quiescente, tuberculoide quiescente, virchowiana reaccional y tuberculoide reaccional. Se observaron diferencias significativas entre lãs formas quiescentes y lãs reaccionales; no se observo diferencia entre lãs formas quiescentes entre si, em tanto que la actividad enzimática em los pacientes virchowianos reaccionales estava elevada com respecto a los tuberculoides reaccionales em forma poço significativa. Se discute que la causa de estas alteraciones se deba a fenômenos de hipersensibilidad mediados por inmunocomplejos o por células segun los casos. Descriptors: HANSENIASE - ENZIMAS Electronic Medium: http://hansen.bvs.ilsl.br/textoc/hansenint/v01aov20/1978/PDF/v3n2/v3n2a04.pdf / Es Location: BR191.1

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Id: 6835 Author: Manalang, J Title: Non-acid-fast forms of MY. leprae in leprotic lesions: second report ..- Source: s.l; s.n; 1938. 9 p. tab, graf. Descriptors: HANSENIASE HANSENIASE - MYCOBACTERIUM LEPRAE  MYCOBACTERIUM LEPRAE Location: BR191.1; 05138/s

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Id: 6706 Author: Bergel, Meny Title: Comportamiento histoquimico del granuloma lepromatoso y de la "Grasa Amarilla" frente al azul de metileno ..- Source: s.l; s.n; s.d. 5 p. ilus. Descriptors: HANSENIASE HANSENIASE - AZUL DE METILENO  GRANULOMA Location: BR191.1; 03834/s

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