Database : HANSEN Search on : CRESCIMENTO [Subject descriptor] References found : 22 [refine] Displaying: 1 .. 20   in format [Detailed]

page 1 de 2

go to page

1 / 22

HANSEN

select to print

Id: 17692 Author: Pesce, Carlo; Grattarola, Myriam; Menini, Stefano; Fiallo, Paolo Title: Short report: Cyclooxygenase 2 expression in vessels and nerves in reversal reaction leprosy ..- Source: s.l; s.n; 2006. 2 p. ilus. Abstract: Tissue expression of cyclooxygenase (COX)2, an inducible enzyme synthesizing eicosanoids in inflammation, was studied in reversal reaction (RR) leprosy in comparison with nonreactionary leprosy. COX2 was consistently expressed in cells of the mononuclear-macrophage lineage across the leprosy spectrum. Only in RR, the following two additional sites showed COX2 expression in the dermis and subcutis: 1) microvessels and 2) nerve bundles and isolated nerve fibers. The same sites also express vascular endothelial growth factor (VEGF). This is in keeping with experimental models relating VEGF to COX2 expression, with VEGF enhancing prostaglandin production through COX2 stimulation and prostaglandin synthase expression. We postulate that selective COX2 inhibitors, which are currently used in several inflammatory conditions, could be considered for RR treatment to reduce acute symptoms caused by tissue edema and possibly prevent long-term nerve damage, the main complication of RR. (AU). Descriptors: Vasos Sanguíneos/EN Ciclooxigenase 2/*BI Inibidores de Ciclooxigenase 2/PD Edema/EN/MI Endotélio/EN Amarelo de Eosina-(ys)/ME Regulação Enzimológica da Expressão Gênica/* Granuloma/EN/MI/PA Hematoxilina/ME Imunoquímica/MT Hanseníase/CL/*EN/PP Mycobacterium leprae/IP Neurônios/EN Nitrobenzenos/PD Pele/BS/*EN/IR/PA Sulfonamidas/PD Fator A de Crescimento do Endotélio Vascular/BI/DE Limits: HUMANO Location: BR191.1; 09360/S

2 / 22

HANSEN

select to print

Id: 13951 Author: Kiszewski, C. A; Becerril, E; Baquera, J; Aguilar, L. D; Hernández-Pando, R Title: Expression of transforming growth factor-beta isoforms and their receptors in lepromatous and tuberculoid leprosy ..- Source: s.l; s.n; 2003. 7 p. ilus, tab, graf. Abstract: Leprosy is an infectious disease with two polar forms, tuberculoid leprosy (TT) and lepromatous leprosy (LL), that are characterized by strong cell-mediated immunity (CMI) and CMI anergy, respectively. Transforming growth factor-beta (TGF-beta) belongs to a family of pleiotropic cytokines (TGF-beta1, TGF-beta2 and TGF-beta3) that participate in the control of cell differentiation and proliferation, as well as tissue repair. This cytokine family is unique because it suppresses CMI. In this study, we compared the expression of the three TGF-beta isoforms and their receptors in skin biopsies from LL and TT patients (LL = 20; TT = 20) using immunohistochemistry and automated morphometry. The percentage of cells immunostained for the three TGF-beta isoforms and cells positive for the three TGF-beta receptors in the inflammatory infiltrate located in the papillary dermis, reticular dermis and periadnexal tissue were significantly higher in LL than that in TT, with macrophages being the most common and strongest immunoreactive cells. Some lymphocytes, fibroblasts, keratinocytes and epithelial cells from sweat glands and hair roots were also positive. In situ reverse-transcription polymerase chain reaction corroborated the capacity of these cells to synthesize TGF-beta1 and TGF-beta receptor 2. This high expression of TGF-beta isoforms and their receptors could contribute to CMI anergy and other clinical characteristic features of leprosy, like skin atrophy. (AU). Descriptors: HANSENIASE VIRCHOWIANA/imunol HANSENIASE VIRCHOWIANA/metab HANSENIASE TUBERCULOIDE/imunol HANSENIASE TUBERCULOIDE/metab MYCOBACTERIUM LEPRAE ISOFORMAS DE PROTEINAS HIBRIDIZACAO IN SITU RNA MENSAGEIRO/quim RNA MENSAGEIRO/genet RECEPTORES DO FATOR DE CRESCIMENTO TRANSFORMADOR BETA/bios RECEPTORES DO FATOR DE CRESCIMENTO TRANSFORMADOR BETA/imunol PELE/citol PELE/imunol REACAO EM CADEIA POR POLIMERASE VIA TRANSCRIPTASE REVERSA IMUNOHISTOQUIMICA BIOPSIA FATOR DE CRESCIMENTO TRANSFORMADOR BETA/bios FATOR DE CRESCIMENTO TRANSFORMADOR BETA/genet FATOR DE CRESCIMENTO TRANSFORMADOR BETA/imunol Limits: HUMANO Electronic Medium: http://www.ilsl.br Location: BR191.1; 09092/s

3 / 22

HANSEN

select to print

Id: 13741 Author: Fiallo, Paolo; Clapasson, Andrea; Favre, Anna; Pesce, Carlo Title: Overexpression of vascular endothelial growth factor and its endothelial cell receptor KDR in type I leprosy reaction ..- Source: s.l; s.n; Feb. 2002. 6 p. ilus, tab. Abstract: The sites of expression of vascular endothelial growth factor (VEGF) and of KDR, its endothelial cell receptor, were investigated in leprosy reaction Type 1, or reversal reaction (RR), by immunohistochemistry and in situ hybridization. In comparison with nonreactional leprosy, overexpression of both VEGF and KDR was seen in granuloma cells, especially epithelioid and foreign body-type giant cells, the epithelium and the vascular endothelium of RR specimens. In granuloma cells, hybridization for VEGF was stronger than immunostaining, a finding that may reflect the rapid turnover of VEGF in an immunologically dynamic situation such as RR. In the epidermis, double immunohistochemistry revealed VEGF overexpression in CDla-positive dendritic cells. The VEGF may not only be relevant for hyperpermeability and mononuclear cell differentiation (the key morphologic features in the acute, clinically evident phase of RR), but it could also be implicated in RR onset, when dendritic cells are activated in response to antigen stimulation. (AU). Descriptors: PRIMERS DO DNA FATORES DE CRESCIMENTO ENDOTELIAL/metab HANSENIASE DIMORFA/metab HANSENIASE DIMORFA/patol RECEPTORES DOS FATORES DE CRESCIMENTO/metab RECEPTORES MITOGÊNICOS/metab LINFOCINAS/metab RECEPTORES PROTEINA TIROSINA QUINASES/metab IMUNOHISTOQUIMICA HIBRIDIZACAO IN SITU - INCLUSAO EM PARAFINA Limits: HUMANO SUPPORT, NON-U.S. GOV'T RECEPTORES DE FATOR DE CRESCIMENTO DO ENDOTELIO VASCULAR Electronic Medium: http://www.ilsl.br Location: BR191.1; 09033/s

4 / 22

HANSEN

select to print

Id: 13378 Author: Duncan, M. E Title: Babies of mothers with leprosy have small placentae, low birth weights and grow slowly ..- Source: s.l; s.n; jun. 1980. 9 p. tab, graf. Abstract: One hundred and sixteen women with leprosy and 31 healthy controls were studied throughout 155 pregnancies, and their babies were observed for a period of up to two years. Babies of mothers with leprosy weighed less than those of healthy mothers; the placental weights and coefficients followed the same trend. The babies of the mothers with leprosy grew more slowly than those of the healthy mothers and these findings were most marked in the babies of mothers with lepromatous leprosy. The cause of the reduced feto-placental weight is thought to be related to the immune status of the mother.(AU). Descriptors: PESO AO NASCER DESENVOLVIMENTO INFANTIL CRESCIMENTO MORTALIDADE INFANTIL HANSENIASE/quimioter HANSENIASE/fisiopatol PESO DOS ORGAOS PLACENTA/anat COMPLICACOES INFECCIOSAS NA GRAVIDEZ/quimioter COMPLICACOES INFECCIOSAS NA GRAVIDEZ/fisiopatol Limits: HUMANO FEMININO GRAVIDEZ RECÉM-NASCIDO LACTENTE ADULTO Electronic Medium: http://www.ilsl.br Location: BR191.1; 01492/s

5 / 22

HANSEN

select to print

Id: 13074 Author: Fuentes, C. Rodriguez Title: Lepra ..- Source: São Paulo; s.n; jul. 1943. 27 p. . Abstract: La lepra, llamada también leontiasis (por la fisionomía o aspecto de león) y elefantiasis (por las deformaciones que produce en los miembros inferiores a los que imprime aspecto de piernas de elefante), es una enfermedad infecciosa producida por la penetración en el organismo de um germen especifico descubierto en 1871 por le medico noruego Gerhard Henrich Hansen.La existencia de la lepra data desde la más remota antiguedad, pues de ella nos hablan ya los libros chinos e indios de hace muchos años pero las primeras descripciones claras de la lepra datan de la era cristiana, siendo los primeros en descubrirla Celso y Areteo. Descriptors: HANSENIASE/prev hanseniase/transmissão hanseniase/historia mycobacterium leprae/crescimento & desenvolvimento hanseniase/diagnostico hanseniase/classificação hanseniase/complicação hanseniase/fisiopatologia Location: BR191.1; 0940/d.a

6 / 22

HANSEN

select to print

Id: 12724 Author: Conference on Leprosy Research. Public Health Service Hospital Carville*. Title: Progress and potentials in leprosy research ..- Source: s.l; s.n; 1956. 9 p. ilus. Conference: Present in: Conference on Leprosy Research. Public Health Service Hospital, Carville, 10-11 January 1945. Descriptors: EVENTOS CIENTIFICOS DE DIVULGACAO MYCOBACTERIUM LEPRAE/isolamento&purificacao MYCOBACTERIUM LEPRAE/crescimento&desenvolvimento MYCOBACTERIUM LEPRAE/metabolismo MYCOBACTERIUM LEPRAE/patogenicidade ANIMAIS DE LABORATORIO/imunologia ANIMAIS DE LABORATORIO/microbiologia Location: BR191.1; 08862/s

7 / 22

HANSEN

select to print

Id: 11973 Author: Anon Title: New light on Hansen's disease: argentine scientist claims success in experimental transmission od Hansen's bacillus to animals ..- Source: s.l; s.n; s.d. 1 p. ilus. Descriptors: MYCOBACTERIUM LEPRAE / isolamento & purificação MYCOBACTERIUM LEPRAE /patogenicidade HANSENÍASE/transmissão - MYCOBACTERIUM LEPRAE /crescimento & desenvolvimento  MYCOBACTERIUM LEPRAE /imunologia  ANIMAIS DE LABORATÓRIO/microbiologia  RATOS Location: BR191.1; 0206/f

8 / 22

HANSEN

select to print

Id: 11947 Author: Fiallo, Paolo; Clapassom, Andrea; Favre, Anna; Pesce, Carlo Title: Overexpression of vascular endothelial growth factor and its endothelial cell receptor KDR in type 1 leprosy reaction ..- Source: s.l; s.n; 2002. 6 p. ilus, tab. Descriptors: HANSENIASE DIMORFA HANSENIASE DIMORFA PRIMERS DO DNA FATORES DE CRESCIMENTO ENDOTELIAL IMUNOHISTOQUIMICA HIBRIDIZAÇAO IN SITU LINFOCINAS INCLUSAO EM PARAFINA RECEPTORES DOS FATORES DE CRESCIMENTO RECEPTORES MITOGENICOS Location: BR191.1; 08598/s

9 / 22

HANSEN

select to print

Id: 11274 Author: Facer, Paul; Mann, Dawn; Mathur, Rajeev; Pandya, Shubha; Ladiwalla, Uma; Singhal, Bhim; Hongo, Jo-Anne; Sinicropi, Dominick V; Terenghi, Giorgio; Anand, Praveen Title: Do nerve growth factor-related mmechanisms contribute to loss of cutaneous nociception in leprosy? ..- Source: s.l; s.n; 2000. 8 p. ilus, graf. Descriptors: AXONIOS CALOR IMUNOHISTOQUIMICA HIBRIDIZAÇAO IN SITU CERATINOCITOS HANSENIASE HANSENIASE HANSENIASE NOCICEPTORES DOR DOR DOR LIMIAR DA DOR ESTIMULAÇAO FISICA RECEPTOR DA PROTEINA TIROSINAQUINASE REFLEXO PELE PELE CANAIS DE SODIO TIOLÉSTER HIDROLASES VASODILATAÇAO FATORES DE CRESCIMENTO NEURAL/ME/*PH Location: BR191.1; 07450/s

10 / 22

HANSEN

select to print

Id: 10379 Author: Singh, N; Birdi, T. J; Antia, N. H Title: Nerve growth factor production and expression of p75 by Schwann cells and neurofibroblasts in response to M. leprae infection and macrophage secretory products ..- Source: s.l; s.n; 1997. 9 p. ilus, tab, graf. Descriptors: ELISA FIBROBLASTOS HANSENIASE MACROFAGOS CAMUNDONGOS CAMUNDONGOS ENDOGAMICOS C57BL PROTEINAS ONCOGENICAS V-FOS CÉLULAS DE SCHWANN Fatores de Crescimento Neural/*ME Limits: ANIMAL Location: BR191.1; 07507/s

11 / 22

HANSEN

select to print

Id: 10333 Author: Anand, P Title: Nerve growth factor regulates nociception in human hhealth and disease ..- Source: s.l; s.n; 1995. 8 p. . Descriptors: DOENÇA AGUDA DOENÇA CRONICA NEUROPATIAS DIABÉTICAS HIPERALGESIA HANSENIASE NOCICEPTORES DOR Fatores de Crescimento Neural/ME/*PH Location: BR191.1; 07184/s

12 / 22

HANSEN

select to print

Id: 10327 Author: Kontochristopoulos, George J; Aroni, Kyriaki; Panteleos, Demetrios N; Tosca, Androniki D Title: Immunohistochemistry in histoid leprosy ..- Source: s.l; s.n; 1995. 5 p. ilus, tab. Descriptors: ANTIGENOS CD1 ANTIGENOS CD36 ANTIGENOS CD45 RELAÇAO CD4-CD8 DAPSONA CÉLULAS DENDRITICAS CÉLULAS DENDRITICAS RESISTENCIA A DROGAS ANTIGENOS HLA-DR IMUNOHISTOQUIMICA CERATINOCITOS CERATINOCITOS HANSENIASE HANSENIASE SUB-POPULAÇOES DE LINFOCITOS RECEPTORES DE CRESCIMENTO EPIDÉRMICO FATOR UROGRASTRONA PELE PELE Location: BR191.1; 07177/s

13 / 22

HANSEN

select to print

Id: 10164 Author: Anand, Praveen Title: Neurotrophins and peripheral neuropathy ..- Source: s.l; s.n; 1996. 6 p. . Descriptors: NEUROPATIAS DIABÉTICAS HIPERALGESIA HANSENIASE NOCICEPTORES NERVOS PERIFÉRICOS DOENÇAS DO SISTEMA NERVOSO PERIFÉRICO FATORES DE CRESCIMENTO NEURAL/*PH/TO Limits: ANIMAL Location: BR191.1; 07077/s

14 / 22

HANSEN

select to print

Id: 10127 Author: Durbeej, Madeleine; Henry, Michael D; Campbell, Kevin P Title: Dystroglycan in development and disease ..- Source: s.l; s.n; 1998. 8 p. ilus, tab. Descriptors: PROTEINAS CITOESQUELETO HANSENIASE GLICOPROTEINAS DE MEMBRANAS CAMUNDONGOS DISTROFIA MUSCULAR RECEPTORES DA SUPERFICIE CELULAR RECEPTORES DOS FATORES DE CRESCIMENTO RECEPTORES DE LAMININA Limits: ANIMAL Location: BR191.1; 07068/s

15 / 22

HANSEN

select to print

Id: 10077 Author: Khanolkar-Young, S; Snowdon, D; Lockwood, D. N. J Title: Immunocytochemical localization of inducible nitric oxide synthase and transforming growth factor-beta (TGF-B) in leprosy lesions ..- Source: s.l; s.n; 1998. 5 p. ilus, tab. Descriptors: HANSENIASE IMUNOHISTOQUIMICA SINTASE DE OXIDO NITRICO FATOR DE CRESCIMENTO TRANSFORMADOR BETA FATOR DE CRESCIMENTO TRANSFORMADOR BETA Location: BR191.1; 07508/s

16 / 22

HANSEN

select to print

Id: 9814 Author: Goulart, Isabela M. B; Figueiredo, Florencio; Coimbra, Terezila; Foss, Norma T Title: Detection of transforming growth factor-B1 in dermal lesions of different clinical froms of leprosy ..- Source: s.l; s.n; 1996. 7 p. ilus, tab. Descriptors: HANSENIASE DIMORFA HANSENIASE DIMORFA HANSENIASE LEPROMATOSA HANSENIASE LEPROMATOSA HANSENIASE TUBERCULOIDE HANSENIASE TUBERCULOIDE BIOPSIA IMUNOHISTOQUIMICA PELE PELE FATOR DE CRESCIMENTO TRANSFORMADOR BETA Location: BR191.1; 06734/s

17 / 22

HANSEN

select to print

Id: 9801 Author: Anand, P; Pandya, S; Ladiwala, U; Singhal, B; Sinicropic, D. V; Williams-Chestnut, R. E Title: Depletion of nerve growth factor in leprosy (Letter) ..- Source: s.l; s.n; 1994. 2 p. . Descriptors: HANSENIASE DIMORFA HANSENIASE HANSENIASE LEPROMATOSA FATORES DE CRESCIMENTO DE NERVOS FATORES DE CRESCIMENTO DE NERVOS PELE Location: BR191.1; 06747/s

18 / 22

HANSEN

select to print

Id: 9768 Author: Crawford, C. L; Hobbs, M. J Title: Neurotrophic factors in diabetic neuropathy ..- Source: s.l; s.n; 1995. 2 p. tab. Descriptors: HANSENIASE NEUROPATIAS DIABÉTICAS NEUROPATIAS DIABÉTICAS FATORES DE CRESCIMENTO DE NERVOS Location: BR191.1; 06780/s

19 / 22

HANSEN

select to print

Id: 9311 Author: Chattopadhya, D; Saha, K; Chakrabarty, A. K; Rao, K. N; Patil, S. K; Sharma, A; Dusaj, I. S Title: Nutritional status of children of urban leprosy patients at preventoria based on biochemical parameters ..- Source: s.l; s.n; 1992. 11 p. ilus, tab. Descriptors: HANSENIASE TRANSTORNOS DO CRESCIMENTO TRANSTORNOS DO CRESCIMENTO TRANSTORNOS DO CRESCIMENTO TRANSTORNOS DA NUTRIÇAO INFANTIL TRANSTORNOS DA NUTRIÇAO INFANTIL TRANSTORNOS DA NUTRIÇAO INFANTIL FILHO DE PAIS INCAPACITADOS CRIANÇA INSTITUCIONALIZADA INDIA AVALIAÇAO NUTRICIONAL INQUÉRITOS NUTRICIONAIS Location: BR191.1. 6488/s

20 / 22

HANSEN

select to print

Id: 7961 Author: Goulart, Isabela Maria Bernardes Title: Produçao de TGF-B1 por células mononucleares do sangue periférico de portadores de hanseníase e seu papel na regulaçao da resposta inflamatória ?- Source: Ribeirao Preto; s.n; 1999. 155 p. ilus, tab, graf. Thesis: Present for Universidade de Sao Paulo. Faculdade de Medicina de Ribeirao Preto presented for the degree Doutor. Abstract: Investigou-se, no presente trabalho, os níveis de TGF-B1 em sobrenadantes de cultura de células aderentes, obtidas de células mononucleares do sangue periférico de voluntários sadios e pacientes com hanseníase, virgens de tratamento. Estas células foram separadas pelo Ficoll-Hypaque após remoçao das plaquetas por lavagem em tampao Versene e centrifugaçao diferencial. Os monócitos foram aderidos em placas de cultura em presença de meio RPMI 1640 suplementado com soro humano AB inativo a 2,5 por cento e cultivados, posteriormente, em meio livre de soro, na presença de LPS ou PGL-1. O TGF-B1 foi mensurado por Elisa nos sobrenadantes colhidos após 48 horas de cultura. Demonstrou-se que as células aderentes dos doentes e dos controles(AU). Descriptors: HANSENIASE HANSENIASE RECEPTORES DO FATOR DE CRESCIMENTO TRANSFORMADOR BETA Location: BR191.1; WC335.500, G729p

---

page 1 de 2

go to page

Refine the search

Database : HANSEN

Advanced form

Search for : Free form

		Search	in field
1			WordsTitle wordsAbstract wordsAuthorInstitutional authorSubject descriptorLimitsLanguageCountry, year publicationJournalType of literatureBibliographic levelMonography in seriesPublication typeConferenceUnique identifierLocationElectronic supportEntry dateRecord type
2	and or and not		WordsTitle wordsAbstract wordsAuthorInstitutional authorSubject descriptorLimitsLanguageCountry, year publicationJournalType of literatureBibliographic levelMonography in seriesPublication typeConferenceUnique identifierLocationElectronic supportEntry dateRecord type
3	and or and not		WordsTitle wordsAbstract wordsAuthorInstitutional authorSubject descriptorLimitsLanguageCountry, year publicationJournalType of literatureBibliographic levelMonography in seriesPublication typeConferenceUnique identifierLocationElectronic supportEntry dateRecord type

Search engine: iAH powered by WWWISIS

IAH - © BIREME/PAHO/WHO Latin American and Caribbean Center on Health Sciences Information