Database : HANSEN
Search on : RELACAO DOSE-RESPOSTA A DROGA [Subject descriptor]
References found : 11 [refine]
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Id:13962
Author:Maslov, A. K; Luzhnova, S. A; Kalyanina, O. V
Title:Effects of horseradish root on functional activity of phagocytes, total blood cell count, and state of the liver in mice with experimental leprosy ..-
Source:s.l; s.n; 2002. 3 p. tab.
Abstract:Therapy of experimental leprosy with dried and grated horseradish root administered perorally in a dose of 300 mg/kg mixed food and treatment with purified horseradish peroxidase increased myeloperoxidase activity of blood neutrophils, enhanced antimicrobial functions of phagocytes, decreased leukocytosis, normalized total blood cell count, and produced no adverse effects on the functional state of the liver in mice. (AU).
Descriptors:CONTAGEM DE CELULAS SANGUINEAS
RELACAO DOSE-RESPOSTA A DROGA
HANSENIASE/imunol
HANSENIASE/fisiopatol
FAGOCITOS/ef drogas
FAGOCITOS/imunol
CAMUNDONGOS ENDOGÂMICOS CBA
FIGADO/ef drogas
FIGADO/imunol
FIGADO/fisiopatol
RAIZES DE PLANTA/quim
ARMORACIA/quim
Limits:ANIMAL
CAMUNDONGOS
Electronic Medium:http://www.ilsl.br
Location:BR191.1; 09146/s


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Id:13356
Author:Shepard, Charles C; Levy, Louis; Fasal, Paul
Title:Further experience with the rapid bactericidal effect of rifampin on Mycobacterium leprae ..-
Source:s.l; s.n; nov. 1974. 5 p. tab, graf.
Abstract:The effect of rifampin therapy in leprosy was studied in two clinical short-term trials in which skin punch biopsy specimens were taken at regular intervals for the inoculation of mice in order to monitor the decrease in proportion of viable Mycobacterium leprae in the patients lesions. In a trial of rifampin in a dosage of 600mg daily, the bacterial viability feel to undectable levels in the first specimen taken after the start of theraphy (at 3-4 days in 4 patients, 7-8 days in 9, and 4 days in 2). Dapsone-treated controls required 20 to more than 112 days for the same change. In a trial of a single dose of 1,500mg rifampin, the viability fell to undetectable levels in the first specimen taken after the start of therapy also (at 3-5 days in all 14 patients).(AU).
Descriptors:FATORES DE TEMPO
HANSENIASE/quimioter
MYCOBACTERIUM LEPRAE/ef drogas
DAPSONA/admin
DAPSONA/farmacol
ENSAIOS CLINICOS
RELACAO DOSE-RESPOSTA A DROGA
BIOPSIA
RIFAMPINA/admin
RIFAMPINA/farmacol
Limits:HUMANO
ANIMAL
CAMUNDONGOS
Electronic Medium:http://www.ilsl.br
Location:BR191.1; 01966/s


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Id:13283
Author:Bahr, G. M; Rook, G. A. W; Stanford, J. L
Title:Prostaglandin-dependent regulation of the in vitro paroliferative response to mycobacterial antigens of peripheral blood lymphocytes from normal donors and from patients with tuberculosis or leprosy ..-
Source:s.l; s.n; sep. 1981. 8 p. tab, graf.
Abstract:The response to soluble mycobacterial antigens of peripheral blood mononuclear cells, from most normal donors, tuberculosis patients or cases of tuberculoid leprosy (TT/BT) was enhanced by the addition of indomethacin. In contrast, indomethacin caused no enhancement of the response of cells from lepromatous leprosy (BL/LL) cases. Moreover the addition of 10-5M prostaglandin E2 (PGE2) failed to inhibit the proliferative responses of cells from the BL/LL patients, although it markedly inhibited the responses of peripheral blood mononuclear cells from the other groups. The addition of PGE2 or indomethacin to cells which had been precultured for 48 hours had no significant effect on the proliferative responses of cells from any of the groups of donors. These results suggest that a normal, prostaglandin-dependent, indomethacin-sensitive regulatory mechanism is absent from the peripheral blood mononuclear cells of BL/LL patients.(AU).
Descriptors:ANTIGENOS DE BACTERIAS/imunol
ANTIGENOS DE FUNGOS/imunol
CANDIDA ALBICANS/imunol
DIVISAO CELULAR/ef drogas
DINOPROSTONA
RELACAO DOSE-RESPOSTA A DROGA
INDOMETACINA/farmacol
HANSENIASE/imunol
TRANSFORMACAO LINFOCITICA/ef drogas
MYCOBACTERIUM/imunol
LINFOCITOS/imunol
Limits:HUMANO
SUPPORT, NON-U.S. GOV'T
Electronic Medium:http://www.ilsl.br
Location:BR191.1; 00540/s


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Id:12225
Author:Cemerski, Saso; cantagrel, Alain; Van Meerwijk, Joost P. M; Romagnoli, Paola
Title:Reactive oxygen species differentially affect T cell receptor-signaling pathways ..-
Source:s.l; s.n; May 2002. 9 p. iluis, tab, graf.
Descriptors:ANTICORPOS MONOCLONAIS
ANTIGENOS CD3
DIVISAO CELULAR
COCULTURA
RELAÇAO DOSE-RESPOSTA A DROGA
CITOMETRIA DE FLUXO
IMMUNOBLOTTING
PROTEINAS DA MEMBRANA
PROTEINAS DA MEMBRANA
NEUTROFILOS
ESTRESSE OXIDATIVO
FOSFORILAÇAO
ESPÉCIES DE OXIGENIO REATIVAS
RECEPTORES DE ANTIGENO DA CÉLULA-T
RECEPTORES DE ANTIGENO DA CÉLULA-T
TRANSDUÇAO DE SINAL
FATORES DE TEMPO
Location:BR191.1; 08708/s


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Id:11941
Author:Baughman, Robert P; Judson, Marc A; Teirstein, Alvin S; Moller, David R; Lower, Elyse E
Title:Thalidomide for chronic sarcoidosis ..-
Source:s.l; s.n; 2002. 6 p. ilus, tab, graf.
Descriptors:SARCOIDOSE
SARCOIDOSE
DERMATOPATIAS
TALIDOMIDA
TALIDOMIDA
DOENÇA CRONICA
RELAÇAO DOSE-RESPOSTA A DROGA
IMUNOSSUPRESSORES
IMUNOSSUPRESSORES
FOTOGRAFIA
Location:BR191.1; 08604/s


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Id:10996
Author:Anon
Title:Thalidomide ..-
Source:s.l; s.n; 1998. 2 p. .
Descriptors:HANSENIASE LEPROMATOSA
HANSENIASE
INFECÇOES OPORTUNISTAS RELACIONADAS COM A AIDS
ANORMALIDADES INDUZIDAS POR DROGAS
ADJUVANTES IMUNOLOGICOS
ANTIINFLAMATORIOS
RELAÇAO DOSE-RESPOSTA A DROGA
NEOVASCULARIZAÇAO FISIOLOGICA
ESTOMATITE AFTOSA
TALIDOMIDA
TALIDOMIDA
TALIDOMIDA
Location:BR191.1; 07344/s


  7 / 11 HANSEN  
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Id:10101
Author:Sampoonachot, Prasert; Bundit, Chaiwut; Kuhacharoen, Nunta; Peerapakorn, Somchai; Kampirapap, Kowit; Poomlek, Arphorn; Bampenyu, Sawanee; Tiasiri, Sirisavapa; Rungruang, Seri; Surasondhi, Somchai; Supanwanit, Sakchai; Wiriyawipart, Srisunthon
Title:Ofloxacin containing combined drug regimens in the treatment of multibacillary leprosy ..-
Source:s.l; s.n; 1997. 8 p. tab.
Descriptors:ADOLESCENCIA
CRIANÇA
RELAÇAO DOSE-RESPOSTA A DROGA
LEPROSTATICOS
LEPROSTATICOS
HANSENIASE
HANSENIASE
CAMUNDONGOS
OFLOXACINA
OFLOXACINA
RIFAMPINA
RIFAMPINA
TAILANDIA
FATORES DE TEMPO
RESULTADO DE TRATAMENTO
CAMUNDONGOS NUS
Limits:ESTUDO COMPARATIVO
ANIMAL
Location:BR191.1; 07042/s


  8 / 11 HANSEN  
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Id:9905
Author:Anon
Title:Relapse following fixed duration treatment for multibacillary leprosy ..-
Source:s.l; s.n; 1994. 2 p. tab, graf.
Descriptors:PAISES EM DESENVOLVIMENTO
RELAÇAO DOSE-RESPOSTA A DROGA
ESQUEMA DE MEDICAÇAO
QUIMIOTERAPIA COMBINADA
SEGUIMENTOS
LEPROSTATICOS
HANSENIASE
HANSENIASE
RECIDIVA
ORGANIZAÇAO MUNDIAL DA SAUDE
Location:BR191.1. 6886/s


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Id:9872
Author:Fernandez, Luis P; Schlegel, Paul G; Baker, Jeanette; Chen, Yanfei; Chao, Nelson J
Title:Does thalidomide affect IL-2 response and production? ..-
Source:s.l; s.n; 1995. 8 p. tab, graf.
Descriptors:TALIDOMIDA
CÉLULAS CLONAIS
RELAÇAO DOSE-RESPOSTA A DROGA
ELEMENTOS DE FACILITAÇAO (GENÉTICA)
ELISA
RECEPTORES DA INTERLEUCINA 2
RECEPTORES DA INTERLEUCINA 2
LINFOCITOS
LINFOCITOS
TRANSFORMAÇAO LINFOCITICA
TRANSFECÇAO
CÉLULAS CULTIVADAS DE TUMOR
BETA-GALACTOSIDASE
BETA-GALACTOSIDASE
Location:BR191.1; 06805/s


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Id:9548
Author:Kaplan, Gilla; Britton, Warwick J; Hancock, Gerald E; Theuvenet, Willem J; Smith, Kendall A; Job, C. K; Roche, Paul W; Molloy, Anthony; Burkhardt, Rochel; Barker, Jeanne; Pradhan, Hira M; Cohn, Zanvil A
Title:The systemic influence of recombinant interleukin 2 on the manifestations of lepromatous leprosy ..-
Source:s.l; s.n; 1991. 14 p. ilus, tab, graf.
Descriptors:ADOLESCENCIA
ANTICORPOS ANTIBACTÉRIAS
ANTIGENOS DE BACTÉRIAS
RELAÇAO DOSE-RESPOSTA A DROGA
IMUNIDADE CELULAR
INTERLEUCINA-2
HANSENIASE LEPROMATOSA
CONTAGEM DE LEUCOCITOS
MICROSCOPIA ELETRONICA
MYCOBACTERIUM LEPRAE
PROTEINAS RECOMBINANTES
FATORES DE TEMPO
Location:BR191.1; 06276/s


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Id:9380
Author:Roche, P. W; Neupane, K. D; Britton, W. J
Title:Cellular immune response to the cell walls of Mycobacterium leprae in leprosy patients and healthy subjects exposed to leprosy ..-
Source:s.l; s.n; 1992. 5 p. tab, graf.
Descriptors:ANTIGENOS DE BACTÉRIAS
ANTIGENOS DE SUPERFICIE
DIVISAO CELULAR
PAREDE CELULAR
RELAÇAO DOSE-RESPOSTA A DROGA
IMUNIDADE CELULAR
HANSENIASE
HANSENIASE
CAMUNDONGOS
MYCOBACTERIUM BOVIS
MYCOBACTERIUM LEPRAE
LINFOCITOS T
VACINAS DE PRODUTOS INATIVADOS
Location:BR191.1; 06401/s



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