Database : HANSEN Search on : RIFAMPINA/FARMACOL [Subject descriptor] References found : 26 [refine] Displaying: 1 .. 20   in format [Detailed]

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Id: 18435 Author: GIRLING, D . J Title: Reaçoes adversas a rifampicina em esquemas contra a tuberculose Adverse reactions to rifampicin in schemes against tuberculosis- Source: s.l; s.n; 1977. 35 p. ilus, tab. Descriptors: RIFAMPINA/ef adv RIFAMPINA/sint quim RIFAMPINA/imunol RIFAMPINA/farmacol RIFAMPINA/uso terap HANSENIASE/quimioter Limits: ESTUDO COMPARATIVO Location: Br191.1; 01217/d.a

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Id: 18224 Author: Guilaine, MM. J; Sterin, D; Despres, E; Lesobre, R Title: Lepre tuberculoide traitee par la rifampicine Leprosy tuberculoide traitement by the rifampicine- Source: s.l; s.n; 1969. 2 p. . Descriptors: HANSENIASE TUBERCULOIDE/quimioter HANSENIASE TUBERCULOIDE/reabil HANSENIASE TUBERCULOIDE/terap RIFAMPINA/sint quim RIFAMPINA/imunol RIFAMPINA/farmacol RIFAMPINA/uso terap Limits: ESTUDO COMPARATIVO Location: BR191.1; 01453/S

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Id: 18140 Author: Gonçalves, Aguinaldo; Gonçalves, Neusa Nunes da Silva e Title: A poliquimioterapia na Hanseniase especial referencia ao Brasil ..- Source: s.l; s.n; 1986. 3 p. . Descriptors: HANSENIASE/quimioter HANSENIASE/reabil HANSENIASE/terap QUIMIOTERAPIA COMBINADA - RIFAMPINA/sint quim  RIFAMPINA/farmacol  RIFAMPINA/uso terap Limits: ESTUDO COMPARATIVO HUMANO Location: BR191.1; 02059/s

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Id: 18090 Author: Sampaio, Sebastiao AP; Rivitti, Evandro A. Title: Hanseníase / Leprosy Source: In: Sampaio, Sebastiao AP; Rivitti, Evandro A.Dermatologia. Sao Paulo, Artes Medicas, 2007. p.625-651ilus, graf. Descriptors: HANSENIASE/imunol HANSENIASE/microbiol HANSENIASE/prev HANSENIASE/fisiopatol HANSENIASE/reabil HANSENIASE/terap MYCOBACTERIUM LEPRAE/citol MYCOBACTERIUM LEPRAE/genet MYCOBACTERIUM LEPRAE/imunol MYCOBACTERIUM LEPRAE/fisiol ANTIGENO DE MITSUDA/quim ANTIGENO DE MITSUDA/fisiol - RIFAMPINA/farmacol  RIFAMPINA/uso terap  DAPSONA/farmacol  DAPSONA/uso terap  CLOFAZIMINA/farmacol  CLOFAZIMINA/uso terap Limits: ESTUDO COMPARATIVO HUMANO Location: Br191.1; WR100, S47d

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Id: 17960 Author: Opromolla, Diltor Vladimir Araujo; Tonello, Claudio Joaquim Sampaio; McDougall, A. Colin; Yawalkar, S. J. Title: Controlled trial to compare therapeutic effects of dapsone in combination with daily or once-monthly rifampin in patients with lepromatous leprosy. Source: In: Sober, Arthur J; Fitzpatrick, Thomas.The year book of dermatology. Chicago, Year Book Medical Publishers, 1983. p.53-54. Descriptors: HANSENIASE/quimioter RIFAMPINA/sint quim RIFAMPINA/farmacol RIFAMPINA/uso terap Limits: ESTUDO COMPARATIVO Location: BR191.1; WR100, S12y

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Id: 13811 Author: Terencio de las Aguas, José. Title: Multiterapia isoprodian-rifampicina. Source: Fontilles - Revista de Leprología;16(1):11-, Ene.-Abr. 1987. . Descriptors: HANSENIASE/quimioter RIFAMPINA/admin RIFAMPINA/farmacol RIFAMPINA/uso terap Location: BR191.1

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Id: 13461 Author: Waters, M. F; Rees, R. J; Pearson, J. M; Laing, A. B; Helmy, H. S; Gelber, R. H Title: Rifampicin for lepromatous leprosy: nine years' experience ..- Source: s.l; s.n; January 21, 1978. 4 p. tab. Abstract: Over 100 patients with lepromatous leprosy were treated with rifampicin in a series of pilot, uncontrolled, and controlled trials in 1968-77. The rapid bactericidal effect of rifampicin on Mycobacterium leprae was confirmed. Clinical improvement became apparent sometimes as early as 14 days after the start of treatment. Nevertheless, a few persisting viable M leprae were detected as long as five years after the start of treatment with rifampicin either by itself or in combination with the bacteriostatic drug thiambutosine. Treatment with rifampicin and dapsone for six months reduced the number of persisting leprosy bacteria more than treatment with dapsone alone. Although rifampicin proved more effective than dapsone, it is unlikely that used by itself if can significantly shorten the length of treatment in lepromatous leprosy. Therefore initial intensive combined treatment with two or more bactericidal drugs (including rifampicin) warrants further investigation in both untreated leprosy and lepromatous leprosy resistant to dapsone.(AU). Descriptors: MYCOBACTERIUM LEPRAE/ef drogas HANSENIASE/quimioter ENSAIOS CLINICOS COMBINACAO DE MEDICAMENTOS DAPSONA/uso terap FENILTIOUREIA/analog FENILTIOUREIA/uso terap RIFAMPINA/admin RIFAMPINA/farmacol RIFAMPINA/uso terap Limits: HUMANO ANIMAL CAMUNDONGOS Electronic Medium: http://www.ilsl.br Location: BR191.1; 01449/s

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Id: 13445 Author: Pilheu, J. A; De Salvo, Maria de C; Barcat, J. A Title: Acción de los esquemas con isoniacida y rifampicina sobre el hígado de enfermos tuberculosos Effect of isoniazid and rifampicin regimens on the liver of tuberculosis patients- Source: s.l; s.n; May-Jun. 1979. 7 p. tab. Abstract: Se estudió un grupo de 86 enfermos tuberculosos que recebieron esquemas terapèuticos con Isoniacida y Rifampicina y se evaluó la acción de esas drogas sobre el hígado. Para ello, antes de iniciar la quimioterapia, se praticó una biopsia hepática y se dosaron transaminasas, fosfatasa y bilirrubina séricas; al finalizar el tercer mes de tratamiento se repitió una biopsia hepática. Los tests funcionales se repitieron mensualmente durante todo el tratamiento. El grupo I (10 casos) recibió Isonacida, Ethambutol y Estreptomicina. En la biopsia inicial hubo 1 caso con transformación grasa y 1 con necrosis focal; al 3er. mes persistía la necrosis focal en 1 caso y apreció en otros 3. El grupo II (14 casos) recibió Rifampicina, Ethambutol y Capreomicina.(AU). Descriptors: QUIMIOTERAPIA COMBINADA ETAMBUTOL/uso terap ISONIAZIDA/admin ISONIAZIDA/farmacol ISONIAZIDA/uso terap RIFAMPINA/admin RIFAMPINA/farmacol RIFAMPINA/uso terap FIGADO/patol Limits: HUMANO MASCULINO FEMININO ADULTO MEIA-IDADE IDOSO ADOLESCENTE RESUMO EM INGLES Electronic Medium: http://www.ilsl.br Location: BR191.1; 00140/s

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Id: 13356 Author: Shepard, Charles C; Levy, Louis; Fasal, Paul Title: Further experience with the rapid bactericidal effect of rifampin on Mycobacterium leprae ..- Source: s.l; s.n; nov. 1974. 5 p. tab, graf. Abstract: The effect of rifampin therapy in leprosy was studied in two clinical short-term trials in which skin punch biopsy specimens were taken at regular intervals for the inoculation of mice in order to monitor the decrease in proportion of viable Mycobacterium leprae in the patients lesions. In a trial of rifampin in a dosage of 600mg daily, the bacterial viability feel to undectable levels in the first specimen taken after the start of theraphy (at 3-4 days in 4 patients, 7-8 days in 9, and 4 days in 2). Dapsone-treated controls required 20 to more than 112 days for the same change. In a trial of a single dose of 1,500mg rifampin, the viability fell to undetectable levels in the first specimen taken after the start of therapy also (at 3-5 days in all 14 patients).(AU). Descriptors: FATORES DE TEMPO HANSENIASE/quimioter MYCOBACTERIUM LEPRAE/ef drogas DAPSONA/admin DAPSONA/farmacol ENSAIOS CLINICOS RELACAO DOSE-RESPOSTA A DROGA BIOPSIA RIFAMPINA/admin RIFAMPINA/farmacol Limits: HUMANO ANIMAL CAMUNDONGOS Electronic Medium: http://www.ilsl.br Location: BR191.1; 01966/s

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Id: 13354 Author: Holmes, I. B; Banerjee, D. K; Hilson, G. R Title: Effect of rifampin, clofazimine, and B1912 on the viability of Mycobacterium leprae in established mouse footpad infection ..- Source: s.l; s.n; apr. 1976. 5 p. graf. Abstract: Continuous dietary administration of rifampin to mice with an established Mycobacterium leprae footpad infection reduced the bacillary solid ratio, with an estimated survival half-life of 5-6 days. In rifampin-treated immunosuppressed animals the survival half-life of solid bacilli, in the absence of host immunity, was 12-13 days. Clofazimine and B1912 produced a significant effect on solid ratio only after a lag period of apparently 100 days. The rate of action was considerably slower than that of rifampin. Intermittent (once monthly) administration of both drugs produced effects similar to those of continuous administration.(AU). Descriptors: ANTICORPOS ANTIBACTERIAS CLOFAZIMINA/analog CLOFAZIMINA/farmacol CLOFAZIMINA/uso terap IMUNOSSUPRESSAO HANSENIASE/quimioter HANSENIASE/imunol MYCOBACTERIUM LEPRAE/ef drogas MYCOBACTERIUM LEPRAE/imunol FATORES DE TEMPO RIFAMPINA/farmacol RIFAMPINA/uso terap Limits: ESTUDO COMPARATIVO ANIMAL CAMUNDONGOS Electronic Medium: http://www.ilsl.br Location: BR191.1; 01652/s

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Id: 13328 Author: Sarma, G. Raghupati; Acharyulu, G. S; Kannapiran, M; Krishna, P. V. Murthy; Gurumurthy, Prema; Tripathy, S. P Title: Role of rifampicin in arthralgia induced by pyrazinamide ..- Source: s.l; s.n; jun. 1983. 8 p. tab, graf. Abstract: Arthralgia during daily treatment with chemotherapy regimens containing pyrazinamide was found to be considerably less in patients who received rifampicin concomitantly...(AU). Descriptors: QUIMIOTERAPIA COMBINADA ARTROPATIAS/ind quim DOR/ind quim RIFAMPINA/farmacol RIFAMPINA/uso terap PIRAZINAMIDA/analog PIRAZINAMIDA/ef adv PIRAZINAMIDA/metab PIRAZINAMIDA/uso terap PIRAZINAMIDA/urina - TUBERCULOSE PULMONAR/quimioter  TUBERCULOSE PULMONAR/metab  ACIDO URICO/urina Electronic Medium: http://www.ilsl.br Location: BR191.1; 01212/s

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Id: 13293 Author: Belda, Walter; Margarido, Leontina C; Marlet, José Maria; Martinez, Ednir A. L. W; Kliemann, Teresa J. A. E; Lombardi, Clóvis; Junior Belda, W Title: Estudo comparativo das médias móveis, dos índices baciloscópico e morfológico, em pacientes de hanseníase virchoviana tratados pela rifampicina e pela diamino-difenil-sulfona Comparative study of the variable averages and bacilloscopic and morphologic indexes in Virchowian Hansen patients treated with rifampicin and diaminediphenylsulfone- Source: s.l; s.n; jun. 1979. 10 p. tab, graf. Abstract: São apresentados resultados clínicos e baciloscópicos obtidos, em estudo comparativo, na experimentação terapêutica da ação da rifampicina e diamino-difenil-sulfona na hanseníase virchoviana. Respectivamente 23 e 24 pacientes, relativamente homogeneizados, foram observados por um período mínimo de 12 meses e máximo de 24. É ressaltada a superioridade da ação da rifampicina, nos primeiros meses, em termos clínicos, e de redução do número de bacilos viáveis. É recomendado, pelo menos como etapa inicial do tratamento, o emprego da rifampicina da terapêutica da hanseníase virchoviana.(AU). Descriptors: HANSENIASE/quimioter HANSENIASE/microbiol HANSENIASE/patol DAPSONA/farmacol DAPSONA/uso terap MYCOBACTERIUM LEPRAE/ef drogas RIFAMPINA/farmacol RIFAMPINA/uso terap Limits: ESTUDO COMPARATIVO HUMANO RESUMO EM INGLES Electronic Medium: http://www.ilsl.br Location: BR191.1; 00588/s

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Id: 13258 Author: Heifets, Leonid B Title: Synergistic effect of rifampin, streptomycin, ethionamide, and ethambutol on Mycobacterium intracellulare ..- Source: s.l; s.n; jan. 1982. 6 p. tab, graf. Abstract: A method of quantitative estimation to determine the interaction of antituberculosis drugs is suggested. The design of experiments, performed on 7H11 agar plates, is adjusted to the following statistical treatment by combined use of probit analysis and isobologram methods. By plotting the values reflecting the inhibition of 75% of the bacterial population (ED75) with their confidence limits on the isobologram, it was found that the clearest results proving synergism between the drugs could be obtained. Six 2-drug combinations and 6 3-drug combinations were tested against strains of Mycobacterium intracellulare (serovar 8), and a synergistic effect was demonstrated in most of them. These were various combinations of rifampin, streptomycin, ethambutol, and ethionamide. The application of probit analysis to the data derived from testing single drugs can provide a quantitative estimation of the actual drug resistance of the M. intracellulare strains.(AU). Descriptors: SINERGISMO DE DROGAS TESTES DE SENSIBILIDADE MICROBIANA MICOBACTERIAS ATIPICAS/ef drogas MYCOBACTERIUM/ef drogas ETAMBUTOL/farmacol ETIONAMIDA/farmacol RIFAMPINA/farmacol ESTREPTOMICINA/farmacol Limits: SUPPORT, NON-U.S. GOV'T Electronic Medium: http://www.ilsl.br Location: BR191.1; 00960/s

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Id: 13223 Author: Pieters, F. A; Woonink, F; Zuidema, J Title: Influence of once-monthly rifampicin and daily clofazimine on the pharmacokinetics of dapsone in leprosy patients in Nigeria ..- Source: s.l; s.n; 1988. 4 p. tab, graf. Abstract: In leprosy patients in Nigeria the influence of daily clofazimine and of once-monthly rifampicin on the pharmacokinetics of dapsone has been investigated. Three days after rifampicin the elimination half-life of dapsone was reduced from 40.4 to 25.3 h (n = 23). Correspondingly, the plasma dapsone 24 h after the last dose had fallen significantly from 2.63 to 2.02 mg/l. Clofazimine did not cause change in the pharmacokinetics of dapsone. It was concluded that, although rifampicin had a considerable influence on the pharmacokinetics of dapsone, there is no reason to adjust the dose of dapsone during multidrug therapy of leprosy.(AU). Descriptors: CLOFAZIMINA/admin CLOFAZIMINA/farmacol HANSENIASE/sangue HANSENIASE/quimioter RIFAMPINA/admin RIFAMPINA/farmacol DAPSONA/admin DAPSONA/sangue DAPSONA/farmacocin DAPSONA/uso terap Limits: HUMANO MASCULINO FEMININO ADULTO MEIA-IDADE IDOSO ADOLESCENTE Electronic Medium: http://www.ilsl.br Location: BR191.1; 02067/s

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Id: 12238 Author: Maeda, Shinji; Matsuoka, Masanori; Nakata, Noboru; Kai, Masanori; Maeda, Yumi; Hashimoto, Ken; Kimura, Hiroaki; Kobayashi, Kazuo; Kashiwabara, Yoshiko Title: Multidrug resistant mycobacterium leprae from patients with leprosy ..- Source: s.l; s.n; Dec. 2001. 5 p. tab, graf. Descriptors: AGENTES ANTIINFECCIOSOS DE FLUOROQUINOLONA AGENTES ANTIINFECCIOSOS DE FLUOROQUINOLONA ANTIBIOTICOS ANTITUBERCULOSE ANTIBIOTICOS ANTITUBERCULOSE SEQUENCIA DE BASES PRIMERS DO DNA DNA BACTERIANO DNA BACTERIANO RESISTENCIA MICROBIANA A DROGAS RESISTENCIA A MULTIPLAS DROGAS GENES BACTERIANOS GENES BACTERIANOS LEPROSTATICOS LEPROSTATICOS HANSENIASE HANSENIASE CAMUNDONGOS DADOS DE SEQUENCIA MOLECULAR MYCOBACTERIUM LEPRAE MYCOBACTERIUM LEPRAE OFLOXACINA OFLOXACINA RIFAMPINA RIFAMPINA REACAO EM CADEIA POR POLIMERASE VIA TRANSCRIPTASE REVERSA Limits: ANIMAL Location: BR191.1; 08640/s

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Id: 11750 Author: Cambau, Emmanuelle; Bonnafous, Pascale; Perani, Evelyne; Sougkoff, Wladimir; Ji, Baohong; Jarlier, Vicent Title: Molecular detection of rifampin and ofloxacin resistance for patients Who experience relapse of multibacillary leprosy ..- Source: s.l; s.n; 2002. 7 p. tab. Descriptors: DNA BACTERIANO MYCOBACTERIUM LEPRAE MYCOBACTERIUM LEPRAE OFLOXACINA RECIDIVA RIFAMPINA ANTIBIOTICOS ANTITUBERCULOSE DNA TOPOISOMERASE (ATP-HIDROLISANTE) DNA TOPOISOMERASE (ATP-HIDROLISANTE) MODELOS ANIMAIS DE DOENÇAS TESTES DE SENSIBILIDADE MICROBIANA HANSENIASE MUTAÇAO PROTEINAS DE PLANTAS PROTEINAS DE PLANTAS Location: BR191.1; 08526/s; BR191.1; 08659/s

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Id: 11445 Author: Consigny, Sophie; Bentoucha, Abdelhalim; Bonnafous, Pascale; Grosset, Jacques; Ji, Baohong Title: Bactericidal activities of HMR 3647, monofloxacin, and rifapentine against mycobacterium leprae in mice ..- Source: s.l; s.n; 2000. 3 p. tab. Descriptors: AGENTES ANTIINFECCIOSOS DE FLUOROQUINOLONA AGENTES ANTIINFECCIOSOS DE FLUOROQUINOLONA ANTIBIOTICOS MACROLIDIOS ANTIBIOTICOS MACROLIDIOS PÉ LEPROSTATICOS LEPROSTATICOS HANSENIASE HANSENIASE CAMUNDONGOS TESTES DE SENSIBILIDADE MICROBIANA MYCOBACTERIUM LEPRAE RIFAMPINA RIFAMPINA RIFAMPINA Limits: ESTUDO COMPARATIVO ANIMAL Location: BR191.1; 08327/s

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Id: 10140 Author: Cambau, Emmanuelle; Perani, Evelyne; Guillemin, Isabelle; Jamet, Pierre; Ji, Baohong Title: Multidrug-resistance to dapsone, rifampicin, and ofloxacin in Mycobacterium leprae ..- Source: s.l; s.n; 1997. 2 p. tab. Descriptors: AGENTES ANTIINFECCIOSOS DE FLUOROQUINOLONA DAPSONA RESISTENCIA A MULTIPLAS DROGAS QUIMIOTERAPIA COMBINADA LEPROSTATICOS HANSENIASE LEPROMATOSA HANSENIASE LEPROMATOSA MYCOBACTERIUM LEPRAE MYCOBACTERIUM LEPRAE OFLOXACINA RIFAMPINA Limits: RELATO DE CASO Location: BR191.1; 07114/s

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Id: 10101 Author: Sampoonachot, Prasert; Bundit, Chaiwut; Kuhacharoen, Nunta; Peerapakorn, Somchai; Kampirapap, Kowit; Poomlek, Arphorn; Bampenyu, Sawanee; Tiasiri, Sirisavapa; Rungruang, Seri; Surasondhi, Somchai; Supanwanit, Sakchai; Wiriyawipart, Srisunthon Title: Ofloxacin containing combined drug regimens in the treatment of multibacillary leprosy ..- Source: s.l; s.n; 1997. 8 p. tab. Descriptors: ADOLESCENCIA CRIANÇA RELAÇAO DOSE-RESPOSTA A DROGA LEPROSTATICOS LEPROSTATICOS HANSENIASE HANSENIASE CAMUNDONGOS OFLOXACINA OFLOXACINA RIFAMPINA RIFAMPINA TAILANDIA FATORES DE TEMPO RESULTADO DE TRATAMENTO CAMUNDONGOS NUS Limits: ESTUDO COMPARATIVO ANIMAL Location: BR191.1; 07042/s

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Id: 9989 Author: Honore, Nadine; Cole, Stewart T Title: Molecular basis of ripampin resistance in mycobacterium leprae ..- Source: s.l; s.n; 1993. 5 p. tab, graf. Descriptors: SEQUENCIA DE AMINOACIDOS SEQUENCIA DE BASES SEQUENCIA CONSERVADA RESISTENCIA MICROBIANA A DROGAS GENES ESTRUTURAIS BACTERIANOS HANSENIASE HANSENIASE HANSENIASE CAMUNDONGOS DADOS DE SEQUENCIA MOLECULAR MUTAÇAO MYCOBACTERIUM LEPRAE MYCOBACTERIUM LEPRAE RIFAMPINA Location: BR191.1; 06633/s

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